DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4282 and ZFP92

DIOPT Version :9

Sequence 1:NP_611118.3 Gene:CG4282 / 36825 FlyBaseID:FBgn0034114 Length:652 Species:Drosophila melanogaster
Sequence 2:NP_001129745.1 Gene:ZFP92 / 139735 HGNCID:12865 Length:416 Species:Homo sapiens


Alignment Length:269 Identity:75/269 - (27%)
Similarity:112/269 - (41%) Gaps:47/269 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly   359 MC--CGRKFTQRKVLAEHVLVHWNPDHFKCSVCEKSFQNSRHLESHQQVHMDPAVKLTFSCDLCS 421
            :|  ||:.|::...|.:|.::|.....:.|..|.|.|:.|..|..||::|   :.:..::|..||
Human   153 LCQQCGKAFSRSSNLIKHRIIHSGEKPYACPECGKLFRRSFALLEHQRIH---SGEKPYACPECS 214

  Fly   422 KTFLSKTAIDYHKLNKHVPKSEFKFTCSECNKKFLTERKLKNHMSSMHDPESTIICDKCGKQMRT 486
            |||...:.:..|::   :...|..|.|.:|.|.|.....|..| :.:|..|....|.:|||....
Human   215 KTFTRSSNLIKHQV---IHSGERPFACGDCGKLFRRSFALLEH-ARVHSGERPYACPECGKAFSR 275

  Fly   487 KIILKKHQELMHSDKPRPEPELQQCQICGAWLKGMTGLKQHMKSIHVESAGEHRCHICAKVSPNA 551
            ...|.:||.....:||      ..|..|....||::.|..|.:|                     
Human   276 SSNLIEHQRTHRGEKP------YACGQCAKAFKGVSQLIHHQRS--------------------- 313

  Fly   552 RALRRHIYHNHECERKFKCTMCEKAFKRPQELKEHTSTHTGEVLYTCPNCPMTFFCSANMYKHRQ 616
                      |..||.|.|..|.|||:....|.:|...|:||..|.|.:|...|...||::|| |
Human   314 ----------HSGERPFACRECGKAFRGRSGLSQHRRVHSGEKPYECSDCGKAFGRRANLFKH-Q 367

  Fly   617 RLHRAQYEA 625
            .:|.|:..|
Human   368 AVHGARRPA 376

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4282NP_611118.3 zf-AD 7..81 CDD:285071
FYDLN_acid <191..268 CDD:302856
C2H2 Zn finger 330..351 CDD:275368
C2H2 Zn finger 360..378 CDD:275368 6/19 (32%)
LIM 361..>400 CDD:295319 11/38 (29%)
C2H2 Zn finger 386..406 CDD:275368 8/19 (42%)
zf-C2H2_8 389..465 CDD:292531 22/75 (29%)
C2H2 Zn finger 417..438 CDD:275368 7/20 (35%)
C2H2 Zn finger 448..465 CDD:275368 5/16 (31%)
C2H2 Zn finger 477..498 CDD:275368 7/20 (35%)
C2H2 Zn finger 511..532 CDD:275368 7/20 (35%)
C2H2 Zn finger 541..562 CDD:275368 0/20 (0%)
C2H2 Zn finger 570..590 CDD:275368 7/19 (37%)
C2H2 Zn finger 598..619 CDD:275368 8/20 (40%)
ZFP92NP_001129745.1 KRAB 14..74 CDD:214630
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 86..125
COG5048 <145..286 CDD:227381 40/139 (29%)
C2H2 Zn finger 154..174 CDD:275368 6/19 (32%)
C2H2 Zn finger 182..202 CDD:275368 8/19 (42%)
C2H2 Zn finger 210..230 CDD:275368 7/22 (32%)
C2H2 Zn finger 238..258 CDD:275368 6/20 (30%)
COG5048 262..>315 CDD:227381 16/89 (18%)
C2H2 Zn finger 266..286 CDD:275368 7/19 (37%)
C2H2 Zn finger 294..314 CDD:275368 7/50 (14%)
C2H2 Zn finger 322..342 CDD:275368 7/19 (37%)
zf-H2C2_2 335..359 CDD:404364 9/23 (39%)
C2H2 Zn finger 350..370 CDD:275368 8/20 (40%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 368..416 3/9 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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