DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4282 and AgaP_AGAP008845

DIOPT Version :9

Sequence 1:	NP_611118.3	Gene:	CG4282 / 36825	FlyBaseID:	FBgn0034114	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	XP_319587.4	Gene:	AgaP_AGAP008845 / 1279808	VectorBaseID:	AGAP008845	Length:	293	Species:	Anopheles gambiae

Alignment Length:	317	Identity:	79/317 - (24%)
Similarity:	132/317 - (41%)	Gaps:	50/317 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   326 SVLPCAIC-------NLL-VHNFT-EMQRHHRLTHQVDPGYMMCCGRKFTQRKVLAEHVLVHWNP 381
            :|.||:.|       .|| :|..: :.:|.|:..|         |.::|..:..||:|:..|...
Mosquito     3 TVFPCSECPRTYPLKQLLDIHQLSHKRERKHQCDH---------CDKRFFSKYDLAKHIATHTGE 58

  Fly   382 DHFKCSVCEKSFQNSRHLESHQQVHMDPAVKLTFSCDLCSKTFLSKTAIDYHKLNKHVPKSEFK- 445
            ..:.|.:|..||..|..|..||..|.|....|   |.||.::||:     ...|.||:...|..
Mosquito    59 RPYVCVICRASFSRSSLLVRHQAKHQDEPKHL---CKLCERSFLT-----VEDLQKHIENHEKSR 115

  Fly   446 -FTCSECNKKFLTERKLKNHMSSMHDPESTIICDKCGKQMRTKIILKKHQELMHSDKPRPEPELQ 509
             :.|:.|.|.|..::.|:.| ..:|..:....|:.|.:...|...|.:|......|:|.|
Mosquito   116 PYHCAHCPKSFAYKQGLERH-EIVHLGKLPFQCEYCEQSFLTAGKLSRHLATHAGDRPYP----- 174

  Fly   510 QCQICGAWLKGMTGLKQHMKSIHVESAGEHRCHICAKVSPNARALRRHIYHN--HECERKFKCTM 572
             |::|.........|.:|::..:.....|::|..|.::   ..:|...:||:  |..| ...|.:
Mosquito   175 -CRLCNKSFLLSHHLSRHLRRHNATGQSEYKCSDCGEL---FNSLGDLVYHSAKHAME-SLTCPL 234

  Fly   573 CEKAFKRPQELKEHTSTHTGEVLYTCPNCPMTFFCSANMYKHRQRL--HRAQYEADK 627
            |.:.|...:.:.||..:|..:..|.|..|.:       ||...|:|  |..|:.|::
Mosquito   235 CLEPFDSVEAVTEHIRSHADQQQYACDYCDL-------MYTSEQKLADHCLQHHANE 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071
		FYDLN_acid	<191..268	CDD:302856
		C2H2 Zn finger	330..351	CDD:275368	7/29 (24%)
		C2H2 Zn finger	360..378	CDD:275368	5/17 (29%)
		LIM	361..>400	CDD:295319	11/38 (29%)
		C2H2 Zn finger	386..406	CDD:275368	8/19 (42%)
		zf-C2H2_8	389..465	CDD:292531	24/77 (31%)
		C2H2 Zn finger	417..438	CDD:275368	6/20 (30%)
		C2H2 Zn finger	448..465	CDD:275368	5/16 (31%)
		C2H2 Zn finger	477..498	CDD:275368	5/20 (25%)
		C2H2 Zn finger	511..532	CDD:275368	4/20 (20%)
		C2H2 Zn finger	541..562	CDD:275368	5/22 (23%)
		C2H2 Zn finger	570..590	CDD:275368	5/19 (26%)
		C2H2 Zn finger	598..619	CDD:275368	6/22 (27%)
AgaP_AGAP008845	XP_319587.4	C2H2 Zn finger	7..27	CDD:275368	5/19 (26%)
		FYDLN_acid	32..>88	CDD:302856	18/64 (28%)
		C2H2 Zn finger	35..55	CDD:275368	6/28 (21%)
		COG5048	<60..223	CDD:227381	45/180 (25%)
		C2H2 Zn finger	63..83	CDD:275368	8/19 (42%)
		C2H2 Zn finger	91..111	CDD:275368	8/24 (33%)
		C2H2 Zn finger	119..139	CDD:275368	6/20 (30%)
		C2H2 Zn finger	147..167	CDD:275368	5/19 (26%)
		C2H2 Zn finger	175..195	CDD:275368	4/19 (21%)
		C2H2 Zn finger	205..225	CDD:275368	5/22 (23%)
		PHA00733	<210..281	CDD:177301	20/81 (25%)
		C2H2 Zn finger	260..276	CDD:275368	6/22 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910