DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4282 and AgaP_AGAP011410

DIOPT Version :9

Sequence 1:	NP_611118.3	Gene:	CG4282 / 36825	FlyBaseID:	FBgn0034114	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	XP_317898.4	Gene:	AgaP_AGAP011410 / 1278283	VectorBaseID:	AGAP011410	Length:	806	Species:	Anopheles gambiae

Alignment Length:	342	Identity:	100/342 - (29%)
Similarity:	153/342 - (44%)	Gaps:	58/342 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   327 VLPCAICNLLVHNFTEMQRHHRLT-HQVDPGYMMC--CGRKFTQRKVLAEHVLVHWNPDHFKCSV 388
            |.||::|:......:.:..||..| |.....| .|  |.::|..:...:.|.|.| :.:.|.|||
Mosquito    25 VFPCSLCDKSYQYKSLLNAHHHGTVHSSSRPY-ACGICSKRFKSQFARSTHELAH-SGNMFPCSV 87

  Fly   389 CEKSFQNSRHLESHQQVHMDPAVKLTFSCDLCSKTFLSKTAIDYH-------------------- 433
            |:||::.:|.|..|.:||.:   ...::|.||.|.|.|..|.:.|
Mosquito    88 CDKSYRYNRDLRHHGRVHSE---NRPYACSLCPKQFKSSFARNTHQHTHSGVRFSCQHCDKSYPY 149

  Fly   434 --KLNKHVPK--SEFKFTCSECNKKFLTERKLKNHMSSMHDPESTIICDKCGKQMRTKIILKKHQ 494
              :|:.|:.|  .|.||.|..|.|.|..:..|:.|:|.||..||...|..|.|:.:|:..|..|.
Mosquito   150 KCQLSIHMRKLHPESKFKCKLCPKIFNHKGSLREHISRMHTYESKYECKLCSKRFKTRRALNIHG 214

  Fly   495 ELMHSDK----------------PRPEPELQ------QCQICGAWLKGMTGLKQHMKSIHVESAG 537
            . :|||.                .|...:|.      .|::|....:..:.|..||:..|.|:
Mosquito   215 R-VHSDNQPYACSYCPKRFKSGYARNTHQLTHTGITFSCELCRKSYRYKSLLNIHMRKHHPEA-- 276

  Fly   538 EHRCHICAKVSPNARALRRHIYHNHECERKFKCTMCEKAFKRPQELKEHTSTHTGEVLYTCPNCP 602
            :.:|.:|.|:..:..:||.||...|..|.|::|.:|.|.|| ..::..|..:|..|..|.||:||
Mosquito   277 KFKCKLCPKIFNHKGSLREHISRMHTYESKYECKLCSKRFK-TSDIVSHIVSHKQEARYACPHCP 340

  Fly   603 MTFFCSANMYKHRQRLH 619
            :....||||.:|.|.:|
Mosquito   341 VRMTHSANMMRHVQAVH 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071
		FYDLN_acid	<191..268	CDD:302856
		C2H2 Zn finger	330..351	CDD:275368	5/21 (24%)
		C2H2 Zn finger	360..378	CDD:275368	5/19 (26%)
		LIM	361..>400	CDD:295319	13/38 (34%)
		C2H2 Zn finger	386..406	CDD:275368	9/19 (47%)
		zf-C2H2_8	389..465	CDD:292531	27/99 (27%)
		C2H2 Zn finger	417..438	CDD:275368	9/42 (21%)
		C2H2 Zn finger	448..465	CDD:275368	5/16 (31%)
		C2H2 Zn finger	477..498	CDD:275368	6/20 (30%)
		C2H2 Zn finger	511..532	CDD:275368	5/20 (25%)
		C2H2 Zn finger	541..562	CDD:275368	7/20 (35%)
		C2H2 Zn finger	570..590	CDD:275368	6/19 (32%)
		C2H2 Zn finger	598..619	CDD:275368	10/20 (50%)
AgaP_AGAP011410	XP_317898.4	C2H2 Zn finger	1..21	CDD:275368
		C2H2 Zn finger	28..50	CDD:275368	5/21 (24%)
		SFP1	<54..133	CDD:227516	27/83 (33%)
		C2H2 Zn finger	58..78	CDD:275368	5/19 (26%)
		C2H2 Zn finger	85..105	CDD:275368	9/19 (47%)
		C2H2 Zn finger	113..133	CDD:275368	8/19 (42%)
		C2H2 Zn finger	140..158	CDD:275368	2/17 (12%)
		C2H2 Zn finger	168..189	CDD:275368	7/20 (35%)
		C2H2 Zn finger	197..217	CDD:275368	6/20 (30%)
		C2H2 Zn finger	225..245	CDD:275368	2/19 (11%)
		C2H2 Zn finger	252..272	CDD:275368	5/19 (26%)
		C2H2 Zn finger	280..301	CDD:275368	7/20 (35%)
		C2H2 Zn finger	336..353	CDD:275368	8/16 (50%)
		C2H2 Zn finger	365..385	CDD:275368
		C2H2 Zn finger	394..414	CDD:275368
		C2H2 Zn finger	422..443	CDD:275368
		C2H2 Zn finger	451..471	CDD:275368
		C2H2 Zn finger	479..499	CDD:275368
		C2H2 Zn finger	506..527	CDD:275368
		C2H2 Zn finger	534..555	CDD:275368
		C2H2 Zn finger	563..580	CDD:275368
		C2H2 Zn finger	592..612	CDD:275368
		C2H2 Zn finger	620..640	CDD:275368
		C2H2 Zn finger	648..668	CDD:275368
		C2H2 Zn finger	675..695	CDD:275368
		C2H2 Zn finger	703..723	CDD:275368
		SFP1	<717..788	CDD:227516
		C2H2 Zn finger	730..748	CDD:275368
		C2H2 Zn finger	767..788	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910