DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4282 and AgaP_AGAP004178

DIOPT Version :9

Sequence 1:	NP_611118.3	Gene:	CG4282 / 36825	FlyBaseID:	FBgn0034114	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	XP_313066.5	Gene:	AgaP_AGAP004178 / 1274001	VectorBaseID:	AGAP004178	Length:	538	Species:	Anopheles gambiae

Alignment Length:	226	Identity:	51/226 - (22%)
Similarity:	76/226 - (33%)	Gaps:	68/226 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   245 PSDNSSEDDGGSDGFDSDSDFELDNGKQEFAVLPKRTVVRPKKYKKRTKPAEPKVRMSRELLEQR 309
            |:.|..|.:|||         ...||..:         .:.||.|||..|.|.|.|..
Mosquito   325 PAANGEEANGGS---------STGNGTGK---------TKTKKQKKRKPPKEKKPRPK------- 364

  Fly   310 KKQQEEYDVIIAKFFTSVLPCAICNLLVHNFTEMQRHHRLTHQVDPGYMMCCGR---KFTQRKVL 371
                               |..|               |.|..:|...:.||..   .:.:|.::
Mosquito   365 -------------------PGQI---------------RETKALDGSPLFCCPECQMAYPERGLI 395

  Fly   372 AEHVLVHWNPDHFKCSVCEKSFQNSRHLESHQQVHMDPAVKLTFSCDLCSKTFLSKTAIDYHKLN 436
            .:||:.|.....|.|.:|..:.:...||..|:..|:.....:   |.:|.|:|..|..:..|.:
Mosquito   396 EQHVISHAVERRFVCDICNAALKRKDHLTRHKLSHIPDRPHI---CSICLKSFKRKEQLTLHVV- 456

  Fly   437 KHVPKSEFKFTCSECNKKFLTERKLKNHMSS 467
              :...|.|..|.||.|.|..:..|:.|..|
Mosquito   457 --IHTGEKKHICGECGKGFYRKDHLRKHTRS 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071
		FYDLN_acid	<191..268	CDD:302856	6/22 (27%)
		C2H2 Zn finger	330..351	CDD:275368	2/20 (10%)
		C2H2 Zn finger	360..378	CDD:275368	5/20 (25%)
		LIM	361..>400	CDD:295319	9/41 (22%)
		C2H2 Zn finger	386..406	CDD:275368	5/19 (26%)
		zf-C2H2_8	389..465	CDD:292531	19/75 (25%)
		C2H2 Zn finger	417..438	CDD:275368	6/20 (30%)
		C2H2 Zn finger	448..465	CDD:275368	6/16 (38%)
		C2H2 Zn finger	477..498	CDD:275368
		C2H2 Zn finger	511..532	CDD:275368
		C2H2 Zn finger	541..562	CDD:275368
		C2H2 Zn finger	570..590	CDD:275368
		C2H2 Zn finger	598..619	CDD:275368
AgaP_AGAP004178	XP_313066.5	C2H2 Zn finger	382..402	CDD:275368	4/19 (21%)
		zf-C2H2_8	383..468	CDD:292531	20/90 (22%)
		C2H2 Zn finger	410..430	CDD:275368	5/19 (26%)
		zf-H2C2_2	422..447	CDD:290200	8/27 (30%)
		C2H2 Zn finger	438..458	CDD:275368	6/22 (27%)
		zf-C2H2	464..486	CDD:278523	8/22 (36%)
		C2H2 Zn finger	466..486	CDD:275368	8/20 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910