DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4282 and AgaP_AGAP005274

DIOPT Version :9

Sequence 1:	NP_611118.3	Gene:	CG4282 / 36825	FlyBaseID:	FBgn0034114	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	XP_309062.5	Gene:	AgaP_AGAP005274 / 1270394	VectorBaseID:	AGAP005274	Length:	636	Species:	Anopheles gambiae

Alignment Length:	318	Identity:	83/318 - (26%)
Similarity:	118/318 - (37%)	Gaps:	81/318 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   339 NFTEMQRH-HRLTHQVDPGYMMCCGRKFTQ-RKVLAEHVLVHWNPDHFKCSVCEKSFQNSRHLES 401
            |.....|| .|::::.    ..||...::: .|..  |..|| ....:.|:.|.|::.:.|.||.
Mosquito     6 NAKSKNRHAKRVSYEC----KTCCKTVYSKSHKQF--HEEVH-RTSRYACNRCNKTYVHKRDLEL 63

  Fly   402 HQQVHMDPAVKLTFSCDLCSKTFLSKTAIDYHKLNKHVPKSEFKFTCSECNKKFLTERKLKNHMS 466
            |.:||..|.   ...|..|:.:|.|...:..||.:|||||.  ||.|..|..||..:..|..|:
Mosquito    64 HHKVHDAPG---RHHCTRCTASFDSAAQLQTHKDSKHVPKE--KFACQLCPLKFTLKGNLTKHL- 122

  Fly   467 SMHDPESTIICDKCGKQ-MRTKIILKKHQELMHSDKPRPEPELQQCQICGAWLKGMTGLKQHMKS 530
            .:||...:..||.|||. :||                                   ..||.||.|
Mosquito   123 IVHDGNRSFSCDVCGKTFLRT-----------------------------------NALKHHMLS 152

  Fly   531 IHVESAGEHRCHICAKVSPNARALRRHIYHNHECERKFKCTMCEKAFKRPQELKEHT-STHTGEV 594
            ..|:   .::|..|.|...:||.|.||: ..|...:.|||::|.....|...:..|. |.|
Mosquito   153 HRVK---RYQCQSCNKEFIDARNLERHL-KTHSRLKGFKCSICGVTSTRKDNIVRHAKSFH---- 209

  Fly   595 LYTCPNCPMTFFCSANMYKHRQRLHRAQYEADKNQPKPPNILKISRNASTQNKPKQEI 652
                |...:.....||     ..:...|.||            |.|.|.|..||:..:
Mosquito   210 ----PESDLKEIVLAN-----GNVSEDQMEA------------IKREAQTSTKPELSV 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071
		FYDLN_acid	<191..268	CDD:302856
		C2H2 Zn finger	330..351	CDD:275368	4/12 (33%)
		C2H2 Zn finger	360..378	CDD:275368	4/18 (22%)
		LIM	361..>400	CDD:295319	9/39 (23%)
		C2H2 Zn finger	386..406	CDD:275368	7/19 (37%)
		zf-C2H2_8	389..465	CDD:292531	27/75 (36%)
		C2H2 Zn finger	417..438	CDD:275368	6/20 (30%)
		C2H2 Zn finger	448..465	CDD:275368	5/16 (31%)
		C2H2 Zn finger	477..498	CDD:275368	7/21 (33%)
		C2H2 Zn finger	511..532	CDD:275368	5/20 (25%)
		C2H2 Zn finger	541..562	CDD:275368	8/20 (40%)
		C2H2 Zn finger	570..590	CDD:275368	5/20 (25%)
		C2H2 Zn finger	598..619	CDD:275368	3/20 (15%)
AgaP_AGAP005274	XP_309062.5	C2H2 Zn finger	21..41	CDD:275370	4/25 (16%)
		C2H2 Zn finger	48..75	CDD:275371	10/29 (34%)
		zf-C2H2_8	51..124	CDD:292531	28/78 (36%)
		C2H2 Zn finger	76..97	CDD:275368	6/20 (30%)
		C2H2 Zn finger	105..125	CDD:275368	6/20 (30%)
		zf-H2C2_2	117..142	CDD:290200	9/25 (36%)
		C2H2 Zn finger	133..153	CDD:275368	11/54 (20%)
		zf-C2H2	158..180	CDD:278523	8/22 (36%)
		C2H2 Zn finger	160..180	CDD:275368	8/20 (40%)
		C2H2 Zn finger	188..204	CDD:275368	3/15 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910