DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4282 and AgaP_AGAP006794

DIOPT Version :9

Sequence 1:	NP_611118.3	Gene:	CG4282 / 36825	FlyBaseID:	FBgn0034114	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	XP_001688142.1	Gene:	AgaP_AGAP006794 / 1270271	VectorBaseID:	AGAP006794	Length:	816	Species:	Anopheles gambiae

Alignment Length:	157	Identity:	46/157 - (29%)
Similarity:	70/157 - (44%)	Gaps:	12/157 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   477 CDKCGKQMRTKIILKKHQELMHSDKPRPEPELQQCQICGAWLKGMTGLKQHMKSIHVESAGEHRC 541
            |.:||||..|...|.:|::   :.:.......::|..||.....|..|..|:.: |..|   |.|
Mosquito   599 CPECGKQYATSSNLSRHKQ---THRSLDSQSAKKCVTCGKAYVSMPALAMHLLT-HKLS---HSC 656

  Fly   542 HICAKVSPNARALRRHIYHNHECERKFKCTMCEKAFKRPQELKEHTSTHTGEVLYTCPNCPMTFF 606
            .:|.|:......|:.|: .:|..|:.:.|..|.|||.....|:.|..||:.:..:.|..|..||.
Mosquito   657 GVCGKLFSRPWLLQGHL-RSHTGEKPYGCGHCGKAFADRSNLRAHMQTHSTDKNFECGRCHKTFA 720

  Fly   607 CSANMYKHRQRLHRAQY-EADKNQPKP 632
            ..:.:.||   |..|.| :.|.|.|.|
Mosquito   721 LKSYLNKH---LESACYKDDDPNGPGP 744

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071
		FYDLN_acid	<191..268	CDD:302856
		C2H2 Zn finger	330..351	CDD:275368
		C2H2 Zn finger	360..378	CDD:275368
		LIM	361..>400	CDD:295319
		C2H2 Zn finger	386..406	CDD:275368
		zf-C2H2_8	389..465	CDD:292531
		C2H2 Zn finger	417..438	CDD:275368
		C2H2 Zn finger	448..465	CDD:275368
		C2H2 Zn finger	477..498	CDD:275368	8/20 (40%)
		C2H2 Zn finger	511..532	CDD:275368	6/20 (30%)
		C2H2 Zn finger	541..562	CDD:275368	5/20 (25%)
		C2H2 Zn finger	570..590	CDD:275368	7/19 (37%)
		C2H2 Zn finger	598..619	CDD:275368	6/20 (30%)
AgaP_AGAP006794	XP_001688142.1	zf-C2H2	597..619	CDD:278523	8/22 (36%)
		C2H2 Zn finger	599..619	CDD:275368	8/22 (36%)
		C2H2 Zn finger	630..647	CDD:275371	5/16 (31%)
		C2H2 Zn finger	656..676	CDD:275368	5/20 (25%)
		zf-H2C2_2	669..692	CDD:290200	8/23 (35%)
		C2H2 Zn finger	684..704	CDD:275368	7/19 (37%)
		zf-C2H2	684..704	CDD:278523	7/19 (37%)
		zf-H2C2_2	696..720	CDD:290200	7/23 (30%)
		C2H2 Zn finger	712..729	CDD:275368	6/19 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910