Protein Alignment CG4282 and ZNF816

DIOPT Version :9

• Sequence 1: NP_611118.3
• Gene: CG4282 / 36825
• FlyBaseID: FBgn0034114
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: NP_001026835.1
• Gene: ZNF816 / 125893
• HGNCID: 26995
• Length: 651
• Species: Homo sapiens
• Alignment Length: 317
• Identity: 94/317 - (29%)
• Similarity: 146/317 - (46%)
• Gaps: 26/317 - (8%)

  Fly   339 NFTEMQRHHRLTHQVDPGYMMC--CGRKFTQRKVLAEHVLVHWNPDHFKCSVCEKSFQNSRHLES 401
            |::.:.|.|.:||..:..| .|  ||:.|.|::.:..|...|.....:||:.|.|:|.....|..
Human   239 NYSSLLRRHHITHSREREY-KCDVCGKIFNQKQYIVYHHRCHTGEKTYKCNECGKTFTQMSSLVC 302

  Fly   402 HQQVHMDPAVKLTFSCDLCSKTFLSKTAIDYHKLNKHVPKSEFKFTCSECNKKFLTERKLKNHMS 466
            |:::|..   :..:.|:.|.|||..|:::..|: ..|..:..:|  |:||.|.|.....|..| .
Human   303 HRRLHTG---EKPYKCNECGKTFSEKSSLRCHR-RLHTGEKPYK--CNECGKTFGRNSALVIH-K 360

  Fly   467 SMHDPESTIICDKCGKQMRTKIILKKHQELMHSDKPRPEPELQQCQICGAWLKGMTGLKQHMKSI 531
            ::|..|....|::|||....|..|:.|..|...:||      .:|:.|.......:.|::|.| |
Human   361 AIHTGEKPYKCNECGKTFSQKSSLQCHHILHTGEKP------YKCEECDNVYIRRSHLERHRK-I 418

  Fly   532 HVESAGEHRCHICAKVSPNARALRRHIYHNHECERKFKCTMCEKAFKRPQELKEHTSTHTGEVLY 596
            |. ..|.::|.:|.||..:...|..| ...|..|:.:||..|.::|.|...|:.|.:.||||..|
Human   419 HT-GEGSYKCKVCDKVFRSDSYLAEH-QRVHTGEKPYKCNKCGRSFSRKSSLQYHHTLHTGEKPY 481

  Fly   597 TCPNCPMTFFCSANMYKHRQRLHRAQ-----YEADKNQPKPPNILKISRNASTQNKP 648
            ||..|...|....|:.:| .|||..:     .|.||...:..: |:..|...|..||
Human   482 TCNECGKVFSRRENLARH-HRLHAGEKPYKCEECDKVFSRRSH-LERHRRIHTGEKP 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071
		FYDLN_acid	<191..268	CDD:302856
		C2H2 Zn finger	330..351	CDD:275368	3/11 (27%)
		C2H2 Zn finger	360..378	CDD:275368	6/19 (32%)
		LIM	361..>400	CDD:295319	11/38 (29%)
		C2H2 Zn finger	386..406	CDD:275368	6/19 (32%)
		zf-C2H2_8	389..465	CDD:292531	21/75 (28%)
		C2H2 Zn finger	417..438	CDD:275368	7/20 (35%)
		C2H2 Zn finger	448..465	CDD:275368	6/16 (38%)
		C2H2 Zn finger	477..498	CDD:275368	8/20 (40%)
		C2H2 Zn finger	511..532	CDD:275368	5/20 (25%)
		C2H2 Zn finger	541..562	CDD:275368	6/20 (30%)
		C2H2 Zn finger	570..590	CDD:275368	6/19 (32%)
		C2H2 Zn finger	598..619	CDD:275368	6/20 (30%)
ZNF816	NP_001026835.1	KRAB	24..64	CDD:307490
		C2H2 Zn finger	232..251	CDD:275368	3/11 (27%)
		C2H2 Zn finger	259..279	CDD:275368	6/19 (32%)
		COG5048	283..650	CDD:227381	81/272 (30%)
		C2H2 Zn finger	287..307	CDD:275368	6/19 (32%)
		C2H2 Zn finger	315..335	CDD:275368	7/20 (35%)
		C2H2 Zn finger	343..363	CDD:275368	7/20 (35%)
		C2H2 Zn finger	371..391	CDD:275368	7/19 (37%)
		C2H2 Zn finger	399..419	CDD:275368	5/20 (25%)
		C2H2 Zn finger	427..447	CDD:275368	6/20 (30%)
		C2H2 Zn finger	455..475	CDD:275368	6/19 (32%)
		C2H2 Zn finger	483..503	CDD:275368	6/20 (30%)
		C2H2 Zn finger	511..531	CDD:275368	5/20 (25%)
		C2H2 Zn finger	539..559	CDD:275368
		C2H2 Zn finger	567..587	CDD:275368
		C2H2 Zn finger	595..615	CDD:275368
		C2H2 Zn finger	623..643	CDD:275368

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910