DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4282 and LOC116406487

DIOPT Version :9

Sequence 1:	NP_611118.3	Gene:	CG4282 / 36825	FlyBaseID:	FBgn0034114	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	XP_031760245.1	Gene:	LOC116406487 / 116406487	-ID:	-	Length:	380	Species:	Xenopus tropicalis

Alignment Length:	396	Identity:	119/396 - (30%)
Similarity:	154/396 - (38%)	Gaps:	76/396 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   268 DNGK---------QEFAVLPKRTVVRPKKYKKRTKPAEPK----------VRMSRELLEQRKKQQ 313
            |:||         ||..:.|..|...|......:..|||.          ..::::...||:...
Frog     4 DHGKSIQVNWLSEQEGPLTPGSTRSFPAILVGLSNTAEPSPLNGTECGETSSLTKDCQGQRRSST 68

  Fly   314 EEYDVIIAKFFTSVLPCAIC-------------NLLVHNFTEMQ--RHHRLTHQV---DPGYMMC 360
            ||      |.|.    ||.|             |:......|.|  |..||||.|   ....:.|
Frog    69 EE------KLFV----CAECGKTSPQNANTGERNITCAQCKETQSFRISRLTHFVIHTGEETITC 123

  Fly   361 --CGRKFTQRKVLAEHVLVHWNPDHFKCSVCEKSFQNSRHLESHQQVHMDPAVKLTFSCDLCSKT 423
              .|:.|.|:..|..|:.:|.....|.|:.|.|.|....:|.||.::|..   :..|:|..|.|.
Frog   124 TESGKGFAQKNYLVSHMKIHTGEKPFTCTECGKGFAQKNYLVSHMKIHTG---EKPFTCTECGKC 185

  Fly   424 FLSKTAIDYHKLNKHVPKSEFKFTCSECNKKFLTERKLKNHMSSMHDPESTIICDKCGKQMRTKI 488
            |..|..:..| |..|.  .|..||||||.|.|..:..|.:|| .:|..|....|.:|||....|.
Frog   186 FAHKNNLVCH-LKIHT--GEKPFTCSECGKGFAQKNDLVSHM-KIHTGEKPFTCTECGKGFIQKN 246

  Fly   489 ILKKHQELMHSDKPRPEPELQQCQICGAWLKGMT---GLKQHMKSIHVESAGE--HRCHICAKVS 548
            .|..|.::...:||      ..|..||   ||.|   .|..||| ||   .||  ..|..|.|..
Frog   247 HLVAHMKIHTGEKP------FTCTECG---KGFTQKNHLVAHMK-IH---TGEKPFTCTECGKGF 298

  Fly   549 PNARALRRHIYHNHECERKFKCTMCEKAFKRPQELKEHTSTHTGEVLYTCPNCPMTFFCSANMYK 613
            .....|..|: ..|..|:.|.||.|.|.|.....|..|...||||.|:||..|.::|...|.:..
Frog   299 TQKNHLVAHM-KIHTGEKPFTCTECGKGFAHKNNLIGHLKIHTGENLFTCTECGISFPEKAILCI 362

  Fly   614 HRQRLH 619
            | |:.|
Frog   363 H-QKFH 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071
		FYDLN_acid	<191..268	CDD:302856	119/396 (30%)
		C2H2 Zn finger	330..351	CDD:275368	9/35 (26%)
		C2H2 Zn finger	360..378	CDD:275368	6/19 (32%)
		LIM	361..>400	CDD:295319	11/38 (29%)
		C2H2 Zn finger	386..406	CDD:275368	7/19 (37%)
		zf-C2H2_8	389..465	CDD:292531	26/75 (35%)
		C2H2 Zn finger	417..438	CDD:275368	7/20 (35%)
		C2H2 Zn finger	448..465	CDD:275368	7/16 (44%)
		C2H2 Zn finger	477..498	CDD:275368	7/20 (35%)
		C2H2 Zn finger	511..532	CDD:275368	10/23 (43%)
		C2H2 Zn finger	541..562	CDD:275368	5/20 (25%)
		C2H2 Zn finger	570..590	CDD:275368	7/19 (37%)
		C2H2 Zn finger	598..619	CDD:275368	6/20 (30%)
LOC116406487	XP_031760245.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910