DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4282 and LOC110437722

DIOPT Version :9

Sequence 1:	NP_611118.3	Gene:	CG4282 / 36825	FlyBaseID:	FBgn0034114	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	XP_021330543.1	Gene:	LOC110437722 / 110437722	-ID:	-	Length:	801	Species:	Danio rerio

Alignment Length:	325	Identity:	93/325 - (28%)
Similarity:	138/325 - (42%)	Gaps:	25/325 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   330 CAICNLLVHNFTEMQRHHRLTHQVDPGYMMCCGRKFTQRKVLAEHVLVHWNPDHFKCSVCEKSFQ 394
            |..|.......:.:.||.::.....|.....||:.|:....|.||:::|.....|.|:.|.|||.
Zfish   395 CTQCGQSFRQTSVLNRHMKIHTGEKPFTCTQCGKSFSYSSSLNEHMVIHTGEKPFTCTQCGKSFS 459

  Fly   395 NSRHLESHQQVHMDPAVKLTFSCDLCSKTFLSKTAIDYHKLNKHVPKSEFKFTCSECNKKFLTER 459
            .|.:|..|..:|:.   :..|.|..|.|:|...:.::.| :..|.  .|..||||:|.|.|....
Zfish   460 RSSNLSQHMMIHVG---EKPFICTQCGKSFCRLSNLNQH-MTTHT--GEKPFTCSQCGKSFSQSS 518

  Fly   460 KLKNHMSSMHDPESTIICDKCGKQMRTKIILKKHQELMHSDKPRPEPELQQCQICGAWLKGMTGL 524
            .|..|: ::|..|....|.:|||.......|.||..:...:||      ..|..||......|.|
Zfish   519 NLNQHL-TIHTGEKPYTCTQCGKSFSQSSSLNKHMMIHTGEKP------FTCSQCGKSFNQSTNL 576

  Fly   525 KQHMKSIHVESAGE--HRCHICAKVSPNARALRRHIYHNHECERKFKCTMCEKAFKRPQELKEHT 587
            ..|| .||   .||  ..|..|.|....:.:|::| ...|..|:.:||:.|:|.|.:...||.|.
Zfish   577 NHHM-MIH---TGETPFTCTQCGKSFSQSSSLKQH-QMIHTGEKPYKCSHCDKRFSQTSHLKAHE 636

  Fly   588 STHTGEVLYTCPNCPMTFFCSANMYKHRQRLHRAQ--YEADKNQPKPPNILKISRNAS--TQNKP 648
            .||||...|.|.:|... |......|..:|:|..:  |:......:..::|.:..:.|  |..||
Zfish   637 RTHTGVKPYKCSHCDKR-FNQLGAQKTHERIHTGEKPYKCSHCSKRFSHLLSLKAHESIHTGEKP 700

Fly 649 648
Zfish 701 700

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071
		FYDLN_acid	<191..268	CDD:302856
		C2H2 Zn finger	330..351	CDD:275368	4/20 (20%)
		C2H2 Zn finger	360..378	CDD:275368	6/17 (35%)
		LIM	361..>400	CDD:295319	14/38 (37%)
		C2H2 Zn finger	386..406	CDD:275368	8/19 (42%)
		zf-C2H2_8	389..465	CDD:292531	24/75 (32%)
		C2H2 Zn finger	417..438	CDD:275368	5/20 (25%)
		C2H2 Zn finger	448..465	CDD:275368	6/16 (38%)
		C2H2 Zn finger	477..498	CDD:275368	7/20 (35%)
		C2H2 Zn finger	511..532	CDD:275368	7/20 (35%)
		C2H2 Zn finger	541..562	CDD:275368	5/20 (25%)
		C2H2 Zn finger	570..590	CDD:275368	7/19 (37%)
		C2H2 Zn finger	598..619	CDD:275368	5/20 (25%)
LOC110437722	XP_021330543.1	COG5048	52..486	CDD:227381	26/93 (28%)
		C2H2 Zn finger	58..78	CDD:275368
		C2H2 Zn finger	86..105	CDD:275368
		C2H2 Zn finger	113..133	CDD:275368
		C2H2 Zn finger	141..163	CDD:275368
		C2H2 Zn finger	171..191	CDD:275368
		C2H2 Zn finger	199..219	CDD:275368
		C2H2 Zn finger	227..247	CDD:275368
		C2H2 Zn finger	255..275	CDD:275368
		C2H2 Zn finger	283..303	CDD:275368
		C2H2 Zn finger	311..331	CDD:275368
		COG5048	335..747	CDD:227381	93/325 (29%)
		C2H2 Zn finger	339..359	CDD:275368
		C2H2 Zn finger	367..387	CDD:275368
		C2H2 Zn finger	395..415	CDD:275368	4/19 (21%)
		C2H2 Zn finger	423..443	CDD:275368	6/19 (32%)
		C2H2 Zn finger	451..471	CDD:275368	8/19 (42%)
		C2H2 Zn finger	479..499	CDD:275368	5/20 (25%)
		C2H2 Zn finger	507..527	CDD:275368	7/20 (35%)
		C2H2 Zn finger	535..555	CDD:275368	7/19 (37%)
		C2H2 Zn finger	563..583	CDD:275368	7/20 (35%)
		C2H2 Zn finger	591..611	CDD:275368	5/20 (25%)
		C2H2 Zn finger	619..639	CDD:275368	7/19 (37%)
		C2H2 Zn finger	647..667	CDD:275368	5/20 (25%)
		C2H2 Zn finger	675..695	CDD:275368	2/19 (11%)
		C2H2 Zn finger	703..723	CDD:275368
		C2H2 Zn finger	731..751	CDD:275368
		C2H2 Zn finger	759..779	CDD:275368
		C2H2 Zn finger	784..800	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910