DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4282 and LOC108648854

DIOPT Version :9

Sequence 1:	NP_611118.3	Gene:	CG4282 / 36825	FlyBaseID:	FBgn0034114	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	XP_017952887.2	Gene:	LOC108648854 / 108648854	-ID:	-	Length:	530	Species:	Xenopus tropicalis

Alignment Length:	489	Identity:	116/489 - (23%)
Similarity:	175/489 - (35%)	Gaps:	93/489 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   217 ED-IQLDLKAEELDEFVDEETDPDFSCLVPSDNSSEDDGGSDGFDSDSDFELDNGKQEFAVLPKR 280
            || :.:.:||    |....|.|..|...:...:.|...|.|  .|:.:..::........::.:.
Frog    11 EDYVSVVVKA----ELASSEGDRHFEDQIQGIDKSTVMGRS--LDNSTTEQIQGTDTPTPIMGRS 69

  Fly   281 TVVRPKKYKKRTKPAEPKVRMSRELLEQRKKQQEEYDVIIAKFFT---------------SVLPC 330
            .|....||.:....:..|..::...|..:....|.:     |.||               ....|
Frog    70 PVKTSNKYDENADTSPDKSGIATNTLCNKYSCNECH-----KHFTDRRKFGKHQGMHKRGKPFSC 129

  Fly   331 AICNLLVHNFTEMQRHHRLTHQVDPGYMMC--CGRKFTQRKVLAEHVLVHWNPDHFKCSVCEKSF 393
            :.|.........:.|||| ||..:..: :|  ||:.|:.:..|.:|...|.....:.||.|.:||
Frog   130 SECGKCFPCRWNLDRHHR-THTGEKPF-LCTECGKCFSCQSDLKKHYRTHTGEKPYSCSECGRSF 192

  Fly   394 QNSRHLESHQQVHMDPAVKLTFSCDLCSKTFLSKTAIDYHKLNKHVPKSEF-------------- 444
            ....||:.|.:.|..   :..|||..|.|.|.|...::.|:...|..:..|
Frog   193 SYQSHLKEHYRTHTG---EKPFSCSECGKCFASLYILNVHQRRTHTGEKPFCCSECGESFAASSE 254

  Fly   445 ------------KFTCSECNKKFLTERKLKNHMSSMHDPESTIICDKCGKQMRTKIILKKHQELM 497
                        .::||||.|.|.....|.||..: |..|....|.:|||....:..||:|....
Frog   255 LTVHRKTHTGEKPYSCSECGKCFSFRSHLYNHRRT-HTKEKPFSCSECGKCFPYQSCLKEHYRTH 318

  Fly   498 HSDKPRPEPELQQCQICGAWLKGMTGLKQHMKSIHVESAGE--HRCHICAKVSPNARALRRHIYH 560
            ..:||      ..|..||.....:..|..|.:..|   :||  ..|..|.|....:..|..|...
Frog   319 TGEKP------FACSDCGKCFAMLYNLNVHHRRTH---SGEKPFSCSDCEKSFATSSDLTSHRRR 374

  Fly   561 NHECERKFKCTMCEKAFKRPQELKEHTSTHTGEVLYTCPNCPMTFFCSANMYKHRQRLHRAQYEA 625
            .|..|:.|.|::|.|.|....||..|..||||:.|:.|..|...|..|:....|::|.|
Frog   375 THTGEKPFSCSICGKCFAFSSELTVHGRTHTGKKLFPCSECGEYFASSSERICHQRRHH------ 433

  Fly   626 DKNQPKP------------PNILKISRNASTQNK 647
               ..||            |:::|......|:.|
Frog   434 ---PKKPFSCSECGKCFSGPSVIKEHLKTQTEEK 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071
		FYDLN_acid	<191..268	CDD:302856	12/51 (24%)
		C2H2 Zn finger	330..351	CDD:275368	6/20 (30%)
		C2H2 Zn finger	360..378	CDD:275368	6/19 (32%)
		LIM	361..>400	CDD:295319	12/38 (32%)
		C2H2 Zn finger	386..406	CDD:275368	8/19 (42%)
		zf-C2H2_8	389..465	CDD:292531	25/101 (25%)
		C2H2 Zn finger	417..438	CDD:275368	6/20 (30%)
		C2H2 Zn finger	448..465	CDD:275368	8/16 (50%)
		C2H2 Zn finger	477..498	CDD:275368	7/20 (35%)
		C2H2 Zn finger	511..532	CDD:275368	5/20 (25%)
		C2H2 Zn finger	541..562	CDD:275368	5/20 (25%)
		C2H2 Zn finger	570..590	CDD:275368	7/19 (37%)
		C2H2 Zn finger	598..619	CDD:275368	6/20 (30%)
LOC108648854	XP_017952887.2	C2H2 Zn finger	101..121	CDD:275368	4/24 (17%)
		COG5048	125..510	CDD:227381	95/364 (26%)
		C2H2 Zn finger	129..149	CDD:275368	6/20 (30%)
		C2H2 Zn finger	157..177	CDD:275368	6/19 (32%)
		C2H2 Zn finger	185..205	CDD:275368	8/19 (42%)
		C2H2 Zn finger	213..234	CDD:275368	6/20 (30%)
		C2H2 Zn finger	242..262	CDD:275368	0/19 (0%)
		C2H2 Zn finger	270..290	CDD:275368	9/20 (45%)
		C2H2 Zn finger	298..318	CDD:275368	7/19 (37%)
		C2H2 Zn finger	326..347	CDD:275368	5/20 (25%)
		C2H2 Zn finger	355..376	CDD:275368	5/20 (25%)
		C2H2 Zn finger	384..404	CDD:275368	7/19 (37%)
		C2H2 Zn finger	412..432	CDD:275368	5/19 (26%)
		C2H2 Zn finger	440..460	CDD:275368	2/19 (11%)
		C2H2 Zn finger	477..497	CDD:275368
		C2H2 Zn finger	505..525	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910