DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4282 and LOC105947126

DIOPT Version :9

Sequence 1:	NP_611118.3	Gene:	CG4282 / 36825	FlyBaseID:	FBgn0034114	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	XP_012817464.2	Gene:	LOC105947126 / 105947126	-ID:	-	Length:	694	Species:	Xenopus tropicalis

Alignment Length:	465	Identity:	114/465 - (24%)
Similarity:	170/465 - (36%)	Gaps:	99/465 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   197 KRRGRPRKSDAAVAPPQKPKEDIQLDLKAEELDEFVDEETDPDFSCLVP---SDNSSEDDGGSD- 257
            ::.|...|...:|...::|       ..:||.:.|.|:....|.|.::.   ..:::|...|:|
Frog    83 QKLGATGKDYISVVVKEEP-------ASSEEDNNFADQIQITDKSTVIRWSLDSSTTEHIQGTDT 140

  Fly   258 -----GF----------DSDSDFELDNGKQEFAV----------------LPKRTVVRPKKYKKR 291
                 ||          |.::|...|  |...|.                ..||...:.::..||
Frog   141 PTPIMGFSLIKTNSNKYDENADTSPD--KSGIATNTLCNKYSCNECHKHFTDKRKFDKHQRVHKR 203

  Fly   292 TKPAEPKVRMSRELLEQRKKQQEEYDVIIAKFFTSVLPCAICNLLVHNFTEMQRHHRLTHQVD-P 355
            .||                                 ..|:.|.......:.:.|||| ||..: |
Frog   204 EKP---------------------------------FSCSECGKSFPCRSNLDRHHR-THTGEKP 234

  Fly   356 GYMMCCGRKFTQRKVLAEHVLVHWNPDHFKCSVCEKSFQNSRHLESHQQVHMDPAVKLTFSCDLC 420
            .:...||:.|:.|..|.:|...|.....:.||.|.|.|....||:.|.:.|..   :..|||..|
Frog   235 FFCSECGKCFSCRSDLKKHCRTHTGEKPYSCSECGKCFSYRSHLKEHYRTHTG---EKPFSCSEC 296

  Fly   421 SKTFLSKTAIDYHKLNKHVPKSEFKFTCSECNKKFLTERKLKNHMSSMHDPESTIICDKCGKQMR 485
            .|:|.|....:.|:...|.  .|..::||||.|.|.....|..|..: |..|....|..|||...
Frog   297 GKSFSSLYMCNVHQRRTHT--GEKPYSCSECGKCFAASSDLTVHHRT-HTGERPFPCPDCGKCFS 358

  Fly   486 TKIILKKHQELMHSDKPRPEPELQQCQICGAWLKGMTGLKQHMKSIHVESAGE--HRCHICAKVS 548
            .:..||:|......:||      ..|..||...    ..:.|:.:.|....||  ..|..|.|..
Frog   359 YRSHLKEHYRTHSGEKP------FSCSECGKCF----SYRSHLNNHHRTHTGEKPFSCSECGKCF 413

  Fly   549 PNARALRRHIYHNHECERKFKCTMCEKAFKRPQELKEH-TSTHTGEVLYTCPNCPMTFFCSANMY 612
            |....|:.| |..|..|:.:.|:.|.|.|.....|..| ..:||||..::|.:|...|..|:::.
Frog   414 PYRSYLKEH-YRTHTGEKPYSCSECGKCFAILYSLSVHQRRSHTGEKPFSCSDCEKCFAASSDLT 477

  Fly   613 KHRQRLHRAQ 622
            .||:|.|..:
Frog   478 SHRRRNHTGE 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071
		FYDLN_acid	<191..268	CDD:302856	17/89 (19%)
		C2H2 Zn finger	330..351	CDD:275368	6/20 (30%)
		C2H2 Zn finger	360..378	CDD:275368	6/17 (35%)
		LIM	361..>400	CDD:295319	13/38 (34%)
		C2H2 Zn finger	386..406	CDD:275368	8/19 (42%)
		zf-C2H2_8	389..465	CDD:292531	24/75 (32%)
		C2H2 Zn finger	417..438	CDD:275368	6/20 (30%)
		C2H2 Zn finger	448..465	CDD:275368	7/16 (44%)
		C2H2 Zn finger	477..498	CDD:275368	7/20 (35%)
		C2H2 Zn finger	511..532	CDD:275368	4/20 (20%)
		C2H2 Zn finger	541..562	CDD:275368	7/20 (35%)
		C2H2 Zn finger	570..590	CDD:275368	6/20 (30%)
		C2H2 Zn finger	598..619	CDD:275368	7/20 (35%)
LOC105947126	XP_012817464.2	C2H2 Zn finger	181..201	CDD:275368	2/19 (11%)
		COG5048	205..609	CDD:227381	90/334 (27%)
		C2H2 Zn finger	209..229	CDD:275368	6/20 (30%)
		C2H2 Zn finger	237..257	CDD:275368	6/19 (32%)
		C2H2 Zn finger	265..285	CDD:275368	8/19 (42%)
		C2H2 Zn finger	293..314	CDD:275368	6/20 (30%)
		C2H2 Zn finger	322..342	CDD:275368	8/20 (40%)
		C2H2 Zn finger	350..370	CDD:275368	7/19 (37%)
		C2H2 Zn finger	378..398	CDD:275368	5/23 (22%)
		C2H2 Zn finger	406..426	CDD:275368	7/20 (35%)
		C2H2 Zn finger	434..452	CDD:275368	6/17 (35%)
		C2H2 Zn finger	463..484	CDD:275368	7/20 (35%)
		C2H2 Zn finger	492..512	CDD:275368
		C2H2 Zn finger	520..540	CDD:275368
		C2H2 Zn finger	548..568	CDD:275368
		C2H2 Zn finger	576..594	CDD:275368
		C2H2 Zn finger	604..624	CDD:275368
		C2H2 Zn finger	641..661	CDD:275368
		C2H2 Zn finger	669..689	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910