DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4282 and si:ch211-229l10.11

DIOPT Version :9

Sequence 1:	NP_611118.3	Gene:	CG4282 / 36825	FlyBaseID:	FBgn0034114	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	XP_021331165.1	Gene:	si:ch211-229l10.11 / 103910550	ZFINID:	ZDB-GENE-110913-131	Length:	850	Species:	Danio rerio

Alignment Length:	354	Identity:	98/354 - (27%)
Similarity:	143/354 - (40%)	Gaps:	58/354 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   330 CAICNLLVHNFTEMQRHHRL-----------------------THQ-VDPGYMMC-----CGRKF 365
            |..|........|::||.|:                       ||: :..|..:|     ||:..
Zfish   460 CLKCENTFITAAELKRHQRVHTGEKPYKCSQCSKRFARSGTLKTHERIHIGEKLCFTCTQCGKSL 524

  Fly   366 TQRKVLAEHVLVHWNPDHFKCSVCEKSFQNSRHLESHQQVHMDPAVKLTFSCDLCSKTFLSKTAI 430
            ..:..|..|:.:|.....|.|:.|.|||..|..|..|.::|..   ::..:|..|.|:|...:.:
Zfish   525 ASKSKLKTHMRIHTGEKPFTCTQCGKSFSKSSSLYRHMKIHTG---EIPLTCTHCGKSFNHSSFL 586

  Fly   431 DYHKLNKHVPKSEFKFTCSECNKKFLTERKLKNHMSSMHDPESTIICDKCGKQMRTKIILKKHQE 495
            :.|   ..:...|...||.:|.|.|.....|..|| .:|..|....|.:|||.......||||..
Zfish   587 NLH---MRIHTGEKPLTCPQCGKSFSKSSSLYKHM-KIHTGEKPFTCTQCGKSFYDSSYLKKHMR 647

  Fly   496 LMHSDKPRPEPELQQCQICGAWLKGMTGLKQHMKSIHVESAGE--HRCHICAKVSPNARALRRHI 558
            :...:||      ..|..||......:.||:|| .||   .||  ..|..|.|....:.:|.||:
Zfish   648 IHTGEKP------FTCAQCGKSFNCSSHLKKHM-MIH---TGEKPFTCTQCGKSFSKSSSLYRHM 702

  Fly   559 YHNHECERKFKCTMCEKAFKRPQELKEHTSTHTGEVLYTCPNCPMTFFCSANMYKHRQRLHRAQY 623
             ..|..|:.|.||.|.|:|.....|.:|...||||..:|||.|..:|..|:|:..| .|:|..:
Zfish   703 -RIHTGEKPFTCTQCGKSFSHSSSLNQHMMIHTGEKPFTCPQCGKSFIHSSNLNLH-MRIHTGE- 764

  Fly   624 EADKNQPKPPNILKISRNASTQNKPKQEI 652
                   ||....:..::.||.:..||.:
Zfish   765 -------KPFTCSQCGKSFSTSSHLKQHM 786

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071
		FYDLN_acid	<191..268	CDD:302856
		C2H2 Zn finger	330..351	CDD:275368	6/43 (14%)
		C2H2 Zn finger	360..378	CDD:275368	5/22 (23%)
		LIM	361..>400	CDD:295319	12/38 (32%)
		C2H2 Zn finger	386..406	CDD:275368	8/19 (42%)
		zf-C2H2_8	389..465	CDD:292531	20/75 (27%)
		C2H2 Zn finger	417..438	CDD:275368	5/20 (25%)
		C2H2 Zn finger	448..465	CDD:275368	5/16 (31%)
		C2H2 Zn finger	477..498	CDD:275368	8/20 (40%)
		C2H2 Zn finger	511..532	CDD:275368	7/20 (35%)
		C2H2 Zn finger	541..562	CDD:275368	6/20 (30%)
		C2H2 Zn finger	570..590	CDD:275368	7/19 (37%)
		C2H2 Zn finger	598..619	CDD:275368	8/20 (40%)
si:ch211-229l10.11	XP_021331165.1	C2H2 Zn finger	12..32	CDD:275368
		zf-H2C2_2	25..49	CDD:316026
		C2H2 Zn finger	40..60	CDD:275368
		C2H2 Zn finger	68..88	CDD:275368
		zf-H2C2_2	80..105	CDD:316026
		SFP1	<90..169	CDD:227516
		C2H2 Zn finger	96..116	CDD:275368
		C2H2 Zn finger	124..144	CDD:275368
		C2H2 Zn finger	152..172	CDD:275368
		COG5048	176..580	CDD:227381	28/122 (23%)
		C2H2 Zn finger	180..200	CDD:275368
		C2H2 Zn finger	208..228	CDD:275368
		C2H2 Zn finger	236..256	CDD:275368
		C2H2 Zn finger	264..284	CDD:275368
		C2H2 Zn finger	292..312	CDD:275368
		C2H2 Zn finger	320..340	CDD:275368
		C2H2 Zn finger	348..368	CDD:275368
		C2H2 Zn finger	376..396	CDD:275368
		COG5048	400..841	CDD:227381	98/354 (28%)
		C2H2 Zn finger	404..424	CDD:275368
		C2H2 Zn finger	432..452	CDD:275368
		C2H2 Zn finger	488..508	CDD:275368	2/19 (11%)
		C2H2 Zn finger	517..537	CDD:275368	4/19 (21%)
		C2H2 Zn finger	545..565	CDD:275368	8/19 (42%)
		C2H2 Zn finger	573..593	CDD:275368	5/22 (23%)
		C2H2 Zn finger	601..621	CDD:275368	7/20 (35%)
		C2H2 Zn finger	629..649	CDD:275368	8/19 (42%)
		C2H2 Zn finger	657..677	CDD:275368	7/20 (35%)
		C2H2 Zn finger	685..705	CDD:275368	6/20 (30%)
		C2H2 Zn finger	713..733	CDD:275368	7/19 (37%)
		C2H2 Zn finger	741..761	CDD:275368	8/20 (40%)
		C2H2 Zn finger	769..789	CDD:275368	4/18 (22%)
		C2H2 Zn finger	797..817	CDD:275368
		C2H2 Zn finger	825..845	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910