DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4282 and LOC102551340

DIOPT Version :9

Sequence 1:	NP_611118.3	Gene:	CG4282 / 36825	FlyBaseID:	FBgn0034114	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	XP_038955362.1	Gene:	LOC102551340 / 102551340	RGDID:	7697243	Length:	948	Species:	Rattus norvegicus

Alignment Length:	361	Identity:	93/361 - (25%)
Similarity:	150/361 - (41%)	Gaps:	69/361 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   330 CAICNLLVHNFTEMQRHHRLTHQVDPGYMMCCGRKFTQRKVLAEHVLVHWNPDHFKCSVCEKSFQ 394
            |.:|....|..:.:.:|.|:.....|.....||:.|.....|::|.::|.....:||.||.|:|.
  Rat   220 CEVCGKAFHYPSILSKHKRIHTGEKPYKCEVCGKAFHISSFLSKHKIIHRGEKPYKCDVCGKAFH 284

  Fly   395 NSRHLESHQQVHMDPAVKLTFSCDLCSKTFLSKTAIDYHKLNKHVPKSEFKFTCSECNKKFLTER 459
            ....|.:|:::|   :.:..:.|::|.|.|...:.:..||: .|..::.:|  |..|.|.|....
  Rat   285 YPSRLSNHKKIH---SGEKPYKCEVCGKAFRILSLLSKHKI-IHTEENPYK--CEVCGKAFDYPS 343

  Fly   460 KLKNHMSSMHDPESTIICDKCGKQMRT----------------------------KIILKKHQEL 496
            :|..| |.||..|....|:.|||..|:                            .:.|.||:::
  Rat   344 RLSTH-SKMHTEEKPYKCEACGKAFRSLSSLSKHRRIHTGDNYYNSEVCGKAFIYPLRLSKHKKI 407

  Fly   497 MHSDKPRPEPELQQCQICGAWLKGMTGLKQHMKSIHVESAGE--HRCHICAKVSPNARALRRHIY 559
            ...:||      .:|::||........|.:| ::||   .||  ::|.:|.|.......|..| .
  Rat   408 CTGEKP------YKCEVCGKAFNDSLVLSKH-RAIH---TGEKLYKCDVCGKAFYYPSRLNNH-R 461

  Fly   560 HNHECERKFKCTMCEKAFKRPQELKEHTSTHTGEVLYTCPNCPMTFFCSANMYKHRQRLHRAQYE 624
            ..|..|:.::|..|.|||..|..|.:|...||||..|.|..|...|...:::.||| |:|..:
  Rat   462 KIHSGEKPYQCEECGKAFCFPSSLSKHKRIHTGEKPYKCKECDKAFRSLSSLSKHR-RIHTGE-- 523

  Fly   625 ADKNQPKP------------PNILKISRNASTQNKP 648
                  ||            |::|...:...|:.||
  Rat   524 ------KPYKCEVCGKAFHYPSLLSKHKITHTEEKP 553

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071
		FYDLN_acid	<191..268	CDD:302856
		C2H2 Zn finger	330..351	CDD:275368	5/20 (25%)
		C2H2 Zn finger	360..378	CDD:275368	5/17 (29%)
		LIM	361..>400	CDD:295319	12/38 (32%)
		C2H2 Zn finger	386..406	CDD:275368	7/19 (37%)
		zf-C2H2_8	389..465	CDD:292531	19/75 (25%)
		C2H2 Zn finger	417..438	CDD:275368	6/20 (30%)
		C2H2 Zn finger	448..465	CDD:275368	5/16 (31%)
		C2H2 Zn finger	477..498	CDD:275368	8/48 (17%)
		C2H2 Zn finger	511..532	CDD:275368	5/20 (25%)
		C2H2 Zn finger	541..562	CDD:275368	5/20 (25%)
		C2H2 Zn finger	570..590	CDD:275368	8/19 (42%)
		C2H2 Zn finger	598..619	CDD:275368	7/20 (35%)
LOC102551340	XP_038955362.1	KRAB	2..60	CDD:214630
		C2H2 Zn finger	108..128	CDD:275368
		SFP1	<131..199	CDD:227516
		C2H2 Zn finger	136..156	CDD:275368
		C2H2 Zn finger	164..184	CDD:275368
		C2H2 Zn finger	192..212	CDD:275368
		COG5048	216..657	CDD:227381	93/361 (26%)
		C2H2 Zn finger	220..240	CDD:275368	5/19 (26%)
		C2H2 Zn finger	248..268	CDD:275368	5/19 (26%)
		C2H2 Zn finger	276..296	CDD:275368	7/19 (37%)
		C2H2 Zn finger	304..324	CDD:275368	6/20 (30%)
		C2H2 Zn finger	332..352	CDD:275368	7/20 (35%)
		C2H2 Zn finger	360..380	CDD:275368	5/19 (26%)
		C2H2 Zn finger	389..408	CDD:275370	3/18 (17%)
		C2H2 Zn finger	416..436	CDD:275368	5/20 (25%)
		C2H2 Zn finger	444..464	CDD:275368	5/20 (25%)
		COG5048	468..910	CDD:227381	28/95 (29%)
		C2H2 Zn finger	472..492	CDD:275368	8/19 (42%)
		C2H2 Zn finger	500..520	CDD:275368	7/20 (35%)
		C2H2 Zn finger	528..548	CDD:275368	2/19 (11%)
		C2H2 Zn finger	556..576	CDD:275368
		C2H2 Zn finger	584..604	CDD:275368
		C2H2 Zn finger	640..660	CDD:275368
		C2H2 Zn finger	668..688	CDD:275368
		C2H2 Zn finger	696..716	CDD:275368
		C2H2 Zn finger	724..744	CDD:275368
		C2H2 Zn finger	752..772	CDD:275368
		C2H2 Zn finger	780..800	CDD:275368
		C2H2 Zn finger	808..828	CDD:275368
		C2H2 Zn finger	836..856	CDD:275368
		C2H2 Zn finger	864..884	CDD:275368
		C2H2 Zn finger	892..912	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910