DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4282 and LOC101886386

DIOPT Version :9

Sequence 1:	NP_611118.3	Gene:	CG4282 / 36825	FlyBaseID:	FBgn0034114	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	XP_021331020.1	Gene:	LOC101886386 / 101886386	-ID:	-	Length:	5627	Species:	Danio rerio

Alignment Length:	335	Identity:	99/335 - (29%)
Similarity:	144/335 - (42%)	Gaps:	37/335 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   322 KFFTSVLPCAICNLLVHNFTEMQRHHRLTHQVDPGYMMCCGRKFTQRKVLAEHVLVHWNPDHFKC 386
            |.||    |..|.......:...:|.|:.....|.....||:.|.....:.||:.:|.....|.|
Zfish  3106 KPFT----CTQCGKSFRQSSSFNKHMRIHTGEKPFTCTQCGKSFNCSSQINEHMRIHTGKKPFTC 3166

  Fly   387 SVCEKSFQNSRHLESHQQVHMDPAVKLTFSCDLCSKTFLSKTAIDYHKLNKH--VPKSEFKFTCS 449
            :.|.|||..|.:|..|.::|..   :..|:|.||.|:|...:     .||||  :...|..|||:
Zfish  3167 TQCGKSFSQSSYLNRHTRIHTG---EKPFTCTLCGKSFNRSS-----NLNKHMRIHTGEKPFTCT 3223

  Fly   450 ECNKKFLTERKLKNHMSSMHDPESTIICDKCGKQMRTKIILKKHQELMHSDKPRPEPELQQCQIC 514
            :|.|.|.....|..|| .:|..|....|.:|||.......|.||..:...:||      ..|..|
Zfish  3224 QCGKSFSVLSSLNLHM-RIHTGEKPFTCTQCGKSFSLSSNLNKHMRIHTGEKP------FTCPQC 3281

  Fly   515 GAWLKGMTGLKQHMKSIHVESAGE--HRCHICAKVSPNARALRRHIYHNHECERKFKCTMCEKAF 577
            |......:.|..||: ||   .||  ..|..|.|....:..|.:|:. :|..|:.|.||.|.|:|
Zfish  3282 GKSFSCSSQLNHHMR-IH---TGEKPFTCTRCGKSFSQSPHLNKHML-SHTGEKPFTCTQCGKSF 3341

  Fly   578 KRPQELKEHTSTHTGEVLYTCPNCPMTFFCSANMYKHRQRLHRAQYEADKNQPKPPNILKISRNA 642
            .:...|.:|...||||..:|||.|..:|:||:::.|| .|:|..:        ||....:..::.
Zfish  3342 SQSSNLNQHMRIHTGEKPFTCPQCGKSFYCSSHLNKH-MRIHTGE--------KPYTCTQCGKSF 3397

  Fly   643 STQNKPKQEI 652
            :..:...|.|
Zfish  3398 NCSSHLNQHI 3407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071
		FYDLN_acid	<191..268	CDD:302856
		C2H2 Zn finger	330..351	CDD:275368	4/20 (20%)
		C2H2 Zn finger	360..378	CDD:275368	5/17 (29%)
		LIM	361..>400	CDD:295319	13/38 (34%)
		C2H2 Zn finger	386..406	CDD:275368	8/19 (42%)
		zf-C2H2_8	389..465	CDD:292531	26/77 (34%)
		C2H2 Zn finger	417..438	CDD:275368	7/20 (35%)
		C2H2 Zn finger	448..465	CDD:275368	5/16 (31%)
		C2H2 Zn finger	477..498	CDD:275368	7/20 (35%)
		C2H2 Zn finger	511..532	CDD:275368	6/20 (30%)
		C2H2 Zn finger	541..562	CDD:275368	5/20 (25%)
		C2H2 Zn finger	570..590	CDD:275368	7/19 (37%)
		C2H2 Zn finger	598..619	CDD:275368	9/20 (45%)
LOC101886386	XP_021331020.1	COG5048	12..420	CDD:227381
		C2H2 Zn finger	12..32	CDD:275368
		C2H2 Zn finger	40..60	CDD:275368
		C2H2 Zn finger	68..88	CDD:275368
		C2H2 Zn finger	96..116	CDD:275368
		C2H2 Zn finger	124..144	CDD:275368
		C2H2 Zn finger	152..172	CDD:275368
		C2H2 Zn finger	180..200	CDD:275368
		C2H2 Zn finger	208..228	CDD:275368
		C2H2 Zn finger	236..256	CDD:275368
		COG5048	260..672	CDD:227381
		C2H2 Zn finger	264..284	CDD:275368
		C2H2 Zn finger	292..312	CDD:275368
		C2H2 Zn finger	320..340	CDD:275368
		C2H2 Zn finger	348..368	CDD:275368
		C2H2 Zn finger	376..396	CDD:275368
		C2H2 Zn finger	404..424	CDD:275368
		C2H2 Zn finger	432..452	CDD:275368
		C2H2 Zn finger	460..480	CDD:275368
		C2H2 Zn finger	488..508	CDD:275368
		C2H2 Zn finger	516..536	CDD:275368
		C2H2 Zn finger	544..564	CDD:275368
		C2H2 Zn finger	572..592	CDD:275368
		C2H2 Zn finger	600..620	CDD:275368
		C2H2 Zn finger	628..648	CDD:275368
		C2H2 Zn finger	656..676	CDD:275368
		C2H2 Zn finger	684..704	CDD:275368
		COG5048	708..1094	CDD:227381
		C2H2 Zn finger	712..732	CDD:275368
		C2H2 Zn finger	740..760	CDD:275368
		C2H2 Zn finger	768..788	CDD:275368
		C2H2 Zn finger	796..816	CDD:275368
		C2H2 Zn finger	824..844	CDD:275368
		C2H2 Zn finger	852..872	CDD:275368
		C2H2 Zn finger	880..903	CDD:275368
		C2H2 Zn finger	911..930	CDD:275370
		C2H2 Zn finger	938..958	CDD:275368
		C2H2 Zn finger	966..986	CDD:275368
		C2H2 Zn finger	994..1014	CDD:275368
		C2H2 Zn finger	1022..1042	CDD:275368
		C2H2 Zn finger	1050..1070	CDD:275368
		C2H2 Zn finger	1078..1098	CDD:275368
		SFP1	<1101..1205	CDD:227516
		C2H2 Zn finger	1106..1126	CDD:275368
		C2H2 Zn finger	1134..1153	CDD:275368
		zf-H2C2_2	1173..1198	CDD:316026
		C2H2 Zn finger	1189..1209	CDD:275368
		C2H2 Zn finger	1217..1237	CDD:275368
		COG5048	1241..1648	CDD:227381
		C2H2 Zn finger	1245..1265	CDD:275368
		C2H2 Zn finger	1273..1293	CDD:275368
		C2H2 Zn finger	1301..1321	CDD:275368
		C2H2 Zn finger	1329..1349	CDD:275368
		C2H2 Zn finger	1357..1377	CDD:275368
		C2H2 Zn finger	1385..1405	CDD:275368
		C2H2 Zn finger	1413..1433	CDD:275368
		C2H2 Zn finger	1441..1461	CDD:275368
		C2H2 Zn finger	1469..1489	CDD:275368
		C2H2 Zn finger	1497..1517	CDD:275368
		C2H2 Zn finger	1525..1545	CDD:275368
		COG5048	1548..>1847	CDD:227381
		C2H2 Zn finger	1553..1573	CDD:275368
		C2H2 Zn finger	1581..1601	CDD:275368
		C2H2 Zn finger	1609..1629	CDD:275368
C2H2 Zn finger	1637..1657	CDD:275368
C2H2 Zn finger	1665..1685	CDD:275368
C2H2 Zn finger	1693..1713	CDD:275368
C2H2 Zn finger	1721..1741	CDD:275368
C2H2 Zn finger	1749..1769	CDD:275368
C2H2 Zn finger	1777..1797	CDD:275368
C2H2 Zn finger	1805..1825	CDD:275368
C2H2 Zn finger	1833..1853	CDD:275368
COG5048	1857..2286	CDD:227381
C2H2 Zn finger	1861..1881	CDD:275368
C2H2 Zn finger	1889..1909	CDD:275368
C2H2 Zn finger	1917..1937	CDD:275368
C2H2 Zn finger	1945..1965	CDD:275368
C2H2 Zn finger	1973..1993	CDD:275368
C2H2 Zn finger	2001..2021	CDD:275368
C2H2 Zn finger	2029..2049	CDD:275368
C2H2 Zn finger	2074..2094	CDD:275368
COG5048	2098..2510	CDD:227381
C2H2 Zn finger	2102..2122	CDD:275368
C2H2 Zn finger	2130..2150	CDD:275368
C2H2 Zn finger	2158..2178	CDD:275368
C2H2 Zn finger	2186..2206	CDD:275368
C2H2 Zn finger	2214..2234	CDD:275368
C2H2 Zn finger	2242..2262	CDD:275368
C2H2 Zn finger	2270..2290	CDD:275368
C2H2 Zn finger	2298..2318	CDD:275368
C2H2 Zn finger	2326..2346	CDD:275368
COG5048	2350..2782	CDD:227381
C2H2 Zn finger	2354..2374	CDD:275368
C2H2 Zn finger	2382..2402	CDD:275368
C2H2 Zn finger	2410..2430	CDD:275368
C2H2 Zn finger	2438..2458	CDD:275368
C2H2 Zn finger	2466..2486	CDD:275368
C2H2 Zn finger	2494..2514	CDD:275368
C2H2 Zn finger	2522..2542	CDD:275368
C2H2 Zn finger	2550..2570	CDD:275368
C2H2 Zn finger	2578..2598	CDD:275368
COG5048	2602..3012	CDD:227381
C2H2 Zn finger	2606..2626	CDD:275368
C2H2 Zn finger	2634..2654	CDD:275368
C2H2 Zn finger	2662..2682	CDD:275368
C2H2 Zn finger	2690..2710	CDD:275368
C2H2 Zn finger	2718..2738	CDD:275368
C2H2 Zn finger	2746..2766	CDD:275368
C2H2 Zn finger	2774..2794	CDD:275368
C2H2 Zn finger	2802..2822	CDD:275368
C2H2 Zn finger	2830..2850	CDD:275368
C2H2 Zn finger	2858..2878	CDD:275368
C2H2 Zn finger	2886..2906	CDD:275368
C2H2 Zn finger	2914..2934	CDD:275368
C2H2 Zn finger	2942..2962	CDD:275368
C2H2 Zn finger	2970..2990	CDD:275368
C2H2 Zn finger	2998..3018	CDD:275368
C2H2 Zn finger	3026..3046	CDD:275368
C2H2 Zn finger	3054..3074	CDD:275368
C2H2 Zn finger	3082..3102	CDD:275368
C2H2 Zn finger	3110..3130	CDD:275368	4/19 (21%)
C2H2 Zn finger	3138..3158	CDD:275368	5/19 (26%)
COG5048	3161..3565	CDD:227381	85/276 (31%)
C2H2 Zn finger	3166..3186	CDD:275368	8/19 (42%)
C2H2 Zn finger	3194..3214	CDD:275368	9/24 (38%)
C2H2 Zn finger	3222..3242	CDD:275368	7/20 (35%)
C2H2 Zn finger	3250..3270	CDD:275368	7/19 (37%)
C2H2 Zn finger	3278..3298	CDD:275368	6/20 (30%)
C2H2 Zn finger	3306..3326	CDD:275368	5/20 (25%)
C2H2 Zn finger	3334..3354	CDD:275368	7/19 (37%)
C2H2 Zn finger	3362..3382	CDD:275368	9/20 (45%)
C2H2 Zn finger	3390..3410	CDD:275368	2/18 (11%)
C2H2 Zn finger	3418..3438	CDD:275368
C2H2 Zn finger	3446..3466	CDD:275368
C2H2 Zn finger	3474..3494	CDD:275368
C2H2 Zn finger	3502..3522	CDD:275368
C2H2 Zn finger	3530..3550	CDD:275368
SFP1	<3553..3657	CDD:227516
C2H2 Zn finger	3558..3578	CDD:275368
C2H2 Zn finger	3586..3605	CDD:275368
C2H2 Zn finger	3641..3661	CDD:275368
C2H2 Zn finger	3669..3689	CDD:275368
C2H2 Zn finger	3697..3717	CDD:275368
C2H2 Zn finger	3725..3745	CDD:275368
zf-H2C2_2	3737..3760	CDD:316026
C2H2 Zn finger	3753..3773	CDD:275368
C2H2 Zn finger	3781..3801	CDD:275368
COG5048	3805..4219	CDD:227381
C2H2 Zn finger	3809..3829	CDD:275368
C2H2 Zn finger	3837..3857	CDD:275368
C2H2 Zn finger	3865..3885	CDD:275368
C2H2 Zn finger	3893..3913	CDD:275368
C2H2 Zn finger	3921..3941	CDD:275368
C2H2 Zn finger	3949..3969	CDD:275368
C2H2 Zn finger	3977..3999	CDD:275368
C2H2 Zn finger	4007..4027	CDD:275368
C2H2 Zn finger	4035..4055	CDD:275368
C2H2 Zn finger	4063..4083	CDD:275368
C2H2 Zn finger	4091..4111	CDD:275368
C2H2 Zn finger	4119..4139	CDD:275368
C2H2 Zn finger	4147..4167	CDD:275368
C2H2 Zn finger	4175..4195	CDD:275368
C2H2 Zn finger	4203..4223	CDD:275368
zf-H2C2_2	4215..4239	CDD:316026
C2H2 Zn finger	4231..4251	CDD:275368
SFP1	<4253..4338	CDD:227516
C2H2 Zn finger	4259..4279	CDD:275368
C2H2 Zn finger	4287..4307	CDD:275368
C2H2 Zn finger	4315..4335	CDD:275368
C2H2 Zn finger	4343..4363	CDD:275368
zf-H2C2_2	4355..4380	CDD:316026
C2H2 Zn finger	4371..4391	CDD:275368
COG5048	4395..4798	CDD:227381
C2H2 Zn finger	4399..4419	CDD:275368
C2H2 Zn finger	4427..4447	CDD:275368
C2H2 Zn finger	4455..4475	CDD:275368
C2H2 Zn finger	4483..4503	CDD:275368
C2H2 Zn finger	4511..4531	CDD:275368
C2H2 Zn finger	4536..4556	CDD:275368
C2H2 Zn finger	4564..4584	CDD:275368
C2H2 Zn finger	4592..4612	CDD:275368
C2H2 Zn finger	4620..4640	CDD:275368
C2H2 Zn finger	4648..4668	CDD:275368
C2H2 Zn finger	4676..4696	CDD:275368
C2H2 Zn finger	4704..4724	CDD:275368
C2H2 Zn finger	4732..4752	CDD:275368
C2H2 Zn finger	4760..4779	CDD:275368
COG5048	4783..5171	CDD:227381
C2H2 Zn finger	4787..4807	CDD:275368
C2H2 Zn finger	4815..4835	CDD:275368
C2H2 Zn finger	4843..4863	CDD:275368
C2H2 Zn finger	4871..4891	CDD:275368
C2H2 Zn finger	4899..4919	CDD:275368
C2H2 Zn finger	4927..4947	CDD:275368
C2H2 Zn finger	4955..4975	CDD:275368
C2H2 Zn finger	4983..5003	CDD:275368
COG5048	5006..5410	CDD:227381
C2H2 Zn finger	5011..5031	CDD:275368
C2H2 Zn finger	5039..5059	CDD:275368
C2H2 Zn finger	5067..5087	CDD:275368
C2H2 Zn finger	5095..5115	CDD:275368
C2H2 Zn finger	5123..5143	CDD:275368
C2H2 Zn finger	5151..5171	CDD:275368
C2H2 Zn finger	5179..5199	CDD:275368
C2H2 Zn finger	5207..5227	CDD:275368
C2H2 Zn finger	5235..5255	CDD:275368
C2H2 Zn finger	5263..5283	CDD:275368
C2H2 Zn finger	5291..5311	CDD:275368
C2H2 Zn finger	5319..5339	CDD:275368
C2H2 Zn finger	5347..5367	CDD:275368
C2H2 Zn finger	5375..5395	CDD:275368
C2H2 Zn finger	5403..5423	CDD:275368
C2H2 Zn finger	5431..5451	CDD:275368
C2H2 Zn finger	5459..5479	CDD:275368
C2H2 Zn finger	5487..5507	CDD:275368
zf-H2C2_2	5499..5524	CDD:316026
C2H2 Zn finger	5515..5535	CDD:275368
C2H2 Zn finger	5543..5563	CDD:275368
C2H2 Zn finger	5599..5619	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910