DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4282 and LOC101885996

DIOPT Version :9

Sequence 1:	NP_611118.3	Gene:	CG4282 / 36825	FlyBaseID:	FBgn0034114	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	XP_005165065.1	Gene:	LOC101885996 / 101885996	-ID:	-	Length:	537	Species:	Danio rerio

Alignment Length:	504	Identity:	131/504 - (25%)
Similarity:	187/504 - (37%)	Gaps:	129/504 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   181 KDEDGVEETAEPAPPKKRRGRPRKSDAAVAPPQKPKEDIQLDLKAEELDE------FVDEETDPD 239
            ||||..|||                ||     .:.||:.:...:|||..|      ||..|.  .
Zfish    19 KDEDAEEET----------------DA-----MEMKEENEALNQAEEKYEYGKRRGFVTGEN--S 60

  Fly   240 FSCLVPSDNSSED------------DGGSDGFDSDSDFE----LDNGKQEF-------AVLPKRT 281
            |||...:|:::.:            :....||..::..:    ...|::.|       :...|.|
Zfish    61 FSCPQLTDSANREPTTTRVEKPFTCEQCGRGFLKNATLKGHMRTHTGEKPFSCQQCGSSFSQKGT 125

  Fly   282 VVRPKKYKKRTKPAEPKVRMSRELLEQRKKQQEEYD-VIIAKFFTSVLPCAICNLLVHNFTEMQR 345
            :.|.::.....||                     |. .:..|.||     |:.||..|    |..
Zfish   126 LTRHQRVHTGEKP---------------------YTCTLCGKGFT-----AVANLTYH----MNI 160

  Fly   346 HHRLTHQVDPGYMMCCGRKFTQRKVLAEHVLVHWNPDHFKCSVCEKSFQNSRHLESHQQVHMDPA 410
            |..|    .|.....||:.|.::|.|:.|:.||...|.|.|..|.:||.|.:.|::|.::|....
Zfish   161 HAGL----KPFTCEQCGKSFRRKKTLSCHMKVHSREDCFICHQCGRSFPNIKCLDTHVKIHSGEK 221

  Fly   411 VKLTFSCDLCSKTFLSKTAIDYHKLNKHVPKSEFKFTCSECNKKFLTERKLKNHMSSMHDPESTI 475
            :   |.|.||.|:|..|..:..|   ..:...|..:||..|.|.|.....||.|| .:|..|...
Zfish   222 L---FDCQLCEKSFRFKVGLKSH---MRIHTGEKPYTCCHCGKDFRFSVSLKTHM-RLHSGEKPY 279

  Fly   476 ICDKCGKQMRTKIILKKHQELMHSDKPRPEPELQQCQICGAWLKGMTGLKQHMKSIHVESAGE-- 538
            .|.:|||..:.|..|..|.. .|:.:..|    ..|::||........||.||: :|   .||
Zfish   280 ACSQCGKSFKYKATLNAHMR-GHTGEESP----HVCKLCGNSFSQKGNLKIHMR-VH---TGEKP 335

  Fly   539 HRCHICAKVSPNARALRRHIYHNHECERKFKCTMCEKAFKRPQELKEHTSTHTGEVLYTCPNCPM 603
            ..|..|.|......:|..|. ..|..||.|||..|.|.|...:.|..|:.||:.|..:.||.|..
Zfish   336 FTCDQCGKSFTRKESLNYHT-RTHSRERGFKCRQCGKCFLYRKNLARHSITHSREKPFICPQCGK 399

  Fly   604 TFFCSANM---------------------YKHRQRL--HRAQYEADKNQ 629
            .|....|:                     :.||:.|  |..::.|.|.|
Zfish   400 GFRFKGNLEVHMSVHAGKKTFQCRKCKKRFTHRKDLKCHLKRHSAKKLQ 448

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071
		FYDLN_acid	<191..268	CDD:302856	17/98 (17%)
		C2H2 Zn finger	330..351	CDD:275368	7/20 (35%)
		C2H2 Zn finger	360..378	CDD:275368	6/17 (35%)
		LIM	361..>400	CDD:295319	15/38 (39%)
		C2H2 Zn finger	386..406	CDD:275368	7/19 (37%)
		zf-C2H2_8	389..465	CDD:292531	23/75 (31%)
		C2H2 Zn finger	417..438	CDD:275368	7/20 (35%)
		C2H2 Zn finger	448..465	CDD:275368	6/16 (38%)
		C2H2 Zn finger	477..498	CDD:275368	7/20 (35%)
		C2H2 Zn finger	511..532	CDD:275368	7/20 (35%)
		C2H2 Zn finger	541..562	CDD:275368	5/20 (25%)
		C2H2 Zn finger	570..590	CDD:275368	6/19 (32%)
		C2H2 Zn finger	598..619	CDD:275368	8/43 (19%)
LOC101885996	XP_005165065.1	COG5048	54..518	CDD:227381	116/448 (26%)
		C2H2 Zn finger	85..105	CDD:275368	2/19 (11%)
		zf-H2C2_2	98..122	CDD:290200	2/23 (9%)
		C2H2 Zn finger	113..133	CDD:275368	3/19 (16%)
		zf-H2C2_2	126..149	CDD:290200	5/43 (12%)
		C2H2 Zn finger	141..161	CDD:275368	8/28 (29%)
		C2H2 Zn finger	169..189	CDD:275368	6/19 (32%)
		C2H2 Zn finger	197..217	CDD:275368	7/19 (37%)
		C2H2 Zn finger	225..245	CDD:275368	7/22 (32%)
		zf-H2C2_2	238..260	CDD:290200	6/24 (25%)
		C2H2 Zn finger	253..273	CDD:275368	8/20 (40%)
		zf-H2C2_2	265..290	CDD:290200	10/25 (40%)
		C2H2 Zn finger	281..301	CDD:275368	7/20 (35%)
		C2H2 Zn finger	310..330	CDD:275368	7/20 (35%)
		zf-H2C2_2	322..347	CDD:290200	10/28 (36%)
		C2H2 Zn finger	338..358	CDD:275368	5/20 (25%)
		C2H2 Zn finger	366..386	CDD:275368	6/19 (32%)
		C2H2 Zn finger	394..414	CDD:275368	5/19 (26%)
		C2H2 Zn finger	422..442	CDD:275368	4/19 (21%)
		C2H2 Zn finger	477..497	CDD:275368
		C2H2 Zn finger	505..522	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910