DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4282 and znf1040

DIOPT Version :9

Sequence 1:	NP_611118.3	Gene:	CG4282 / 36825	FlyBaseID:	FBgn0034114	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	XP_017211075.1	Gene:	znf1040 / 101884948	ZFINID:	ZDB-GENE-141210-11	Length:	420	Species:	Danio rerio

Alignment Length:	443	Identity:	108/443 - (24%)
Similarity:	165/443 - (37%)	Gaps:	99/443 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   213 QKPKEDIQLD----LKAEELDEFVD-----EETDPDFSCLVPSDNSSEDDGGSDGFDSDSDFELD 268
            ::..||::::    :|.|:|.|..|     |||.                 |.:..|....||
Zfish     5 KEESEDVKIEETFTVKQEDLQEQTDLMVLKEETH-----------------GQNEIDEKQQFE-- 50

  Fly   269 NGKQEFAVLPKRTVVRPKKYKKRTKPAEPKVRMSRELLEQRKKQQEEYDVIIAKFFTSVLPCAIC 333
             ..||.....|.|:.  ||.....:|.:.|...:                         ..|..|
Zfish    51 -KPQEIMTDEKPTLT--KKTSSHGRPRKSKSGCN-------------------------FSCKQC 87

  Fly   334 NLLVHNFTEMQRHHRLTHQVDPGYMMCCGRKFTQRKVLAEHVLVHWNPDHFKCSVCEKSFQNSRH 398
            :......:::..|.|:..:..|.....||:.|.|::....|:.:|.....|.|..|.|||.::.:
Zfish    88 SKSFSQKSKLDVHMRVHTREQPFTCEQCGKSFGQKQGFKAHMRIHTGKRKFTCQQCGKSFYHAGN 152

  Fly   399 LESHQQVHMDPAVKLTFSCDLCSKTFLSKTAIDYH-----------------------KLNKH-- 438
            ..:|.::|..   :..|||..|.|:|..|..:|.|                       ..|.|
Zfish   153 FAAHMRIHTG---EKPFSCKQCGKSFCHKPNLDVHMRVHTGEKPYTCEQCGRSFGQKQSFNTHMR 214

  Fly   439 VPKSEFKFTCSECNKKFLTERKLKNHMSSMHDPESTIICDKCGKQMRTKIILKKHQELMHSDKPR 503
            :...:...||.:|.|.|...|.|..||.: |..|....|..|||....|:.|..|..:...:||
Zfish   215 IHTGKRPCTCQQCEKSFYNARSLAAHMIT-HTGERPFSCILCGKSFSLKLTLIAHMRVHTREKP- 277

  Fly   504 PEPELQQCQICGAWLKGMTGLKQHMKSIHVESAGE--HRCHICAKVSPNARALRRHIYHNHECER 566
                 ..|:.||........|..||: ||   .||  :.|..|.|..|:..:|:.|| ..|..|:
Zfish   278 -----HICEQCGKSFGQKQDLDIHMR-IH---TGEKPYTCTECGKSFPHISSLKHHI-RTHTGEK 332

  Fly   567 KFKCTMCEKAFKRPQELKEHTSTHTGEVLYTCPNCPMTFFCSANMYKHRQRLH 619
            .|.|..|.|:|.....||.|.:.|||.:::||..|..:.....::.|| .::|
Zfish   333 PFTCAQCGKSFTTKTSLKNHMNGHTGTIVFTCDQCGKSLTRKDSITKH-MKIH 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071
		FYDLN_acid	<191..268	CDD:302856	14/63 (22%)
		C2H2 Zn finger	330..351	CDD:275368	4/20 (20%)
		C2H2 Zn finger	360..378	CDD:275368	5/17 (29%)
		LIM	361..>400	CDD:295319	12/38 (32%)
		C2H2 Zn finger	386..406	CDD:275368	6/19 (32%)
		zf-C2H2_8	389..465	CDD:292531	24/100 (24%)
		C2H2 Zn finger	417..438	CDD:275368	8/43 (19%)
		C2H2 Zn finger	448..465	CDD:275368	6/16 (38%)
		C2H2 Zn finger	477..498	CDD:275368	7/20 (35%)
		C2H2 Zn finger	511..532	CDD:275368	6/20 (30%)
		C2H2 Zn finger	541..562	CDD:275368	7/20 (35%)
		C2H2 Zn finger	570..590	CDD:275368	7/19 (37%)
		C2H2 Zn finger	598..619	CDD:275368	4/20 (20%)
znf1040	XP_017211075.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910