DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4282 and si:ch1073-127d16.1

DIOPT Version :9

Sequence 1:	NP_611118.3	Gene:	CG4282 / 36825	FlyBaseID:	FBgn0034114	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	XP_021323944.1	Gene:	si:ch1073-127d16.1 / 101883863	ZFINID:	ZDB-GENE-120214-30	Length:	454	Species:	Danio rerio

Alignment Length:	433	Identity:	106/433 - (24%)
Similarity:	163/433 - (37%)	Gaps:	77/433 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   221 LDLKAEELDEFVDEETDPDFSCLVPSDNSSEDDGGSDGFDSDSDFELDNG--------------- 270
            :|:|.||.|            |:      |.|......|......::..|
Zfish     1 MDIKEEEED------------CV------SHDSQSGPYFTEQPSLKIQTGDIFTPIQSLESHKVN 47

  Fly   271 ---KQEFAVLPKRTVVRPKKYKKR-----------TKPAEPKVRMSRELLEQRKKQQEEYDVIIA 321
               ||.|...........|:|.|.           |.|...|....:..||..           .
Zfish    48 HSEKQTFICAECGKSFTLKRYLKNHMKIHTGAHPFTCPECDKCFTMKHSLETH-----------L 101

  Fly   322 KFFTSVLP--CAICNLLVHNFTEMQRHHRLTHQVDPGYMMCCGRKFTQRKVLAEHVLVHWNPDHF 384
            |..|...|  |..|.........:..|.|:.....|.....|||.|.::::|.:|:.:|.....:
Zfish   102 KIHTGEKPFTCPDCGKKFRLKQSLDGHLRIHTGEKPYTCQVCGRSFREKQILDKHLTIHTGEKPY 166

  Fly   385 KCSVCEKSFQNSRHLESHQQVHMDPAVKLTFSCDLCSKTFLSKTAIDYHKLNKHVPKSEFKFTCS 449
            .|..|.|||:....||:|.::|..   :..::|..|.|:|..|..::.| :..|.  .|..|.|.
Zfish   167 SCPECGKSFRVKNCLENHIKIHTG---EKPYTCQECGKSFTEKQNLERH-IRIHT--GEKPFACP 225

  Fly   450 ECNKKFLTERKLKNHMSSMHDPESTIICDKCGKQMRTKIILKKHQELMHSDKPRPEPELQQCQIC 514
            ||.:.|..::.||.|: .:|..|....|.:|||.......|:.|..:...:||      ..|..|
Zfish   226 ECGRSFRVKQDLKIHL-RIHTGEKPFSCQQCGKSFSENKKLENHMRIHTGEKP------FVCSHC 283

  Fly   515 GAWLKGMTGLKQHMKSIHVESAGEHRCHICAKVSPNARALRRHIYHNHECERKFKCTMCEKAFKR 579
            |...:|...|:.||: :|..:. .:.|..|.|.....::|:.|| ..|..|:.|.|..|.|:|.:
Zfish   284 GKNFRGKQNLESHMR-LHTGNQ-PYTCPQCGKSYNQQKSLQIHI-RTHTGEKPFACDQCGKSFTQ 345

  Fly   580 PQELKEHTSTHTGEVLYTCPNCPMTFFCSANMYKHRQRLHRAQ 622
            ...||.|...||||..:|||.|..:|.....:.:|: ::|..:
Zfish   346 QSTLKGHIKIHTGEKPFTCPQCGKSFIEKTKLERHK-KIHSGE 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071
		FYDLN_acid	<191..268	CDD:302856	9/46 (20%)
		C2H2 Zn finger	330..351	CDD:275368	4/20 (20%)
		C2H2 Zn finger	360..378	CDD:275368	6/17 (35%)
		LIM	361..>400	CDD:295319	12/38 (32%)
		C2H2 Zn finger	386..406	CDD:275368	8/19 (42%)
		zf-C2H2_8	389..465	CDD:292531	23/75 (31%)
		C2H2 Zn finger	417..438	CDD:275368	6/20 (30%)
		C2H2 Zn finger	448..465	CDD:275368	6/16 (38%)
		C2H2 Zn finger	477..498	CDD:275368	6/20 (30%)
		C2H2 Zn finger	511..532	CDD:275368	7/20 (35%)
		C2H2 Zn finger	541..562	CDD:275368	6/20 (30%)
		C2H2 Zn finger	570..590	CDD:275368	7/19 (37%)
		C2H2 Zn finger	598..619	CDD:275368	5/20 (25%)
si:ch1073-127d16.1	XP_021323944.1	COG5048	36..445	CDD:227381	96/380 (25%)
		C2H2 Zn finger	56..76	CDD:275368	3/19 (16%)
		C2H2 Zn finger	84..104	CDD:275368	5/30 (17%)
		C2H2 Zn finger	112..132	CDD:275368	4/19 (21%)
		C2H2 Zn finger	140..160	CDD:275368	6/19 (32%)
		C2H2 Zn finger	168..188	CDD:275368	8/19 (42%)
		C2H2 Zn finger	196..216	CDD:275368	6/20 (30%)
		C2H2 Zn finger	224..244	CDD:275368	7/20 (35%)
		C2H2 Zn finger	252..272	CDD:275368	6/19 (32%)
		C2H2 Zn finger	280..300	CDD:275368	7/20 (35%)
		C2H2 Zn finger	308..328	CDD:275368	6/20 (30%)
		C2H2 Zn finger	336..356	CDD:275368	7/19 (37%)
		C2H2 Zn finger	364..384	CDD:275368	5/20 (25%)
		C2H2 Zn finger	392..412	CDD:275368
		C2H2 Zn finger	420..440	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910