DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4282 and zgc:174574

DIOPT Version :9

Sequence 1:	NP_611118.3	Gene:	CG4282 / 36825	FlyBaseID:	FBgn0034114	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	XP_009289655.2	Gene:	zgc:174574 / 101882695	ZFINID:	ZDB-GENE-030131-1529	Length:	385	Species:	Danio rerio

Alignment Length:	428	Identity:	103/428 - (24%)
Similarity:	159/428 - (37%)	Gaps:	104/428 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   213 QKPKEDIQLD----LKAEELDE-FVDEETDPDFSC-LVP-SDNSSEDDGGSDGFDSDSDFELDNG 270
            ::..|||:::    :|.||.:| |..:..||:... |:| .|.|.|.:...:....:...:|.:|
Zfish    44 KEESEDIKIEETFTVKHEETEEAFRVKHEDPEEQTELMPLKDESQEQNETEETVQDEGCLDLRSG 108

  Fly   271 KQEFAVLPKRTVVRPKKYKKRTKPAEPKVRMSRELLEQRKKQQEEYDVIIAKFFTSVLPCAICNL 335
                                             |..||.:..|:..:            ...|
Zfish   109 ---------------------------------EASEQTETSQKTAE------------SNTC-- 126

  Fly   336 LVHNFTEMQRHHRLTHQVDPGYMMCCGRKFTQRKVLAEHVLVHWNPDHFKCSVCEKSFQNSRHLE 400
                      ||             ||:.||:::.|..|:.:|.....|||..|.|.|...::..
Zfish   127 ----------HH-------------CGKSFTRKQYLTNHMRIHNGERPFKCHQCVKIFTQKQNFL 168

  Fly   401 SHQQVHMDPAVKLTFSCDLCSKTFLSKTAIDYHKLNKHVPKSEFKFTCSECNKKFLTERKLKNHM 465
            .|.::|..   :..::|..|.|:|..|..:..|   ..:...|..:||.||.|.|..:..|..||
Zfish   169 DHMRIHTG---EKPYTCQQCGKSFTWKRYLITH---TRMHTGEKPYTCQECGKCFARKHMLTIHM 227

  Fly   466 SSMHDPESTIICDKCGKQMRTKIILKKHQELMHSDKPRPEPELQQCQICG---AWLKGMTGLKQH 527
             .:|..|....|.:|||....|.||..|..:...::|      ..||.||   .|.:..|   :|
Zfish   228 -RVHTGERPYPCQECGKGFTQKHILIDHMRIHTGERP------HVCQQCGMSFTWKQYYT---EH 282

  Fly   528 MKSIHVESAGE--HRCHICAKVSPNARALRRHIYHNHECERKFKCTMCEKAFKRPQELKEHTSTH 590
            |::    ..||  |.|..|.|.....:.|..|: ..|..|:.|.|..|.|.|.....|:.|...|
Zfish   283 MRT----HTGERPHACLQCGKNFTCKQNLTDHM-RIHTGEKPFTCQQCGKCFTCKPNLRSHMKVH 342

  Fly   591 TGEVLYTCPNCPMTFFCSANMYKHRQRLHRAQYEADKN 628
            |||..:.|..|..::....|:.:| .|:|.....:|.|
Zfish   343 TGERPHACSQCGKSYPWKKNLKEH-MRVHTGDQLSDAN 379

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071
		FYDLN_acid	<191..268	CDD:302856	15/61 (25%)
		C2H2 Zn finger	330..351	CDD:275368	3/20 (15%)
		C2H2 Zn finger	360..378	CDD:275368	6/17 (35%)
		LIM	361..>400	CDD:295319	13/38 (34%)
		C2H2 Zn finger	386..406	CDD:275368	5/19 (26%)
		zf-C2H2_8	389..465	CDD:292531	19/75 (25%)
		C2H2 Zn finger	417..438	CDD:275368	6/20 (30%)
		C2H2 Zn finger	448..465	CDD:275368	6/16 (38%)
		C2H2 Zn finger	477..498	CDD:275368	8/20 (40%)
		C2H2 Zn finger	511..532	CDD:275368	8/23 (35%)
		C2H2 Zn finger	541..562	CDD:275368	5/20 (25%)
		C2H2 Zn finger	570..590	CDD:275368	6/19 (32%)
		C2H2 Zn finger	598..619	CDD:275368	5/20 (25%)
zgc:174574	XP_009289655.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910