DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4282 and LOC100537361

DIOPT Version :9

Sequence 1:	NP_611118.3	Gene:	CG4282 / 36825	FlyBaseID:	FBgn0034114	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	XP_003198540.5	Gene:	LOC100537361 / 100537361	-ID:	-	Length:	911	Species:	Danio rerio

Alignment Length:	297	Identity:	89/297 - (29%)
Similarity:	131/297 - (44%)	Gaps:	21/297 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   328 LPCAICNLLVHNFTEMQRHHRLTHQVDPGYMMCCGRKFTQRKVLAEHVLVHWNPDHFKCSVCEKS 392
            :.|..|.......:.:.:|.|:.....|.....||:.|.|...|.:|:.:|.....|.|:.|..|
Zfish   567 ITCTQCGKSFRQSSSLYKHMRIHTGEKPFTCTQCGKSFRQTSSLNKHMRIHTGEKPFTCTQCGIS 631

  Fly   393 FQNSRHLESHQQVHMDPAVKLTFSCDLCSKTFLSKTAIDYHKLNKHVPKSEFKFTCSECNKKFLT 457
            |..|.:|:.|.::|..   :..|:|..|.::|...:.:|:|   ..:...|..|||::|.|.|..
Zfish   632 FNCSSYLKQHMRIHTG---EKPFTCTQCGRSFNRSSNLDHH---MRIHTGEKPFTCTQCGKSFNR 690

  Fly   458 ERKLKNHMSSMHDPESTIICDKCGKQMRTKIILKKHQELMHSDKPRPEPELQQCQICGAWLKGMT 522
            ...|..|: .:|..|..|.|..|||..|....|.||......:||      ..|..||......:
Zfish   691 SSNLDQHI-RIHTGEKPITCTLCGKSFRQSSSLSKHMRTHTGEKP------FTCTQCGKSFNRSS 748

  Fly   523 GLKQHMKSIHVESAGE--HRCHICAKVSPNARALRRHIYHNHECERKFKCTMCEKAFKRPQELKE 585
            .|.||:: ||   .||  ..|..|.|....|.:|.:|: ..|..|:.|.||.|.|:|.|...|.:
Zfish   749 NLDQHIR-IH---TGEKPFTCTQCGKSFRQASSLNKHM-RTHTGEKPFTCTQCGKSFNRSSHLNQ 808

  Fly   586 HTSTHTGEVLYTCPNCPMTFFCSANMYKHRQRLHRAQ 622
            |...||||....|..|..:|..|:::||| .|:|..:
Zfish   809 HIRIHTGEKPIMCTQCGKSFRQSSSLYKH-MRIHTGE 844

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071
		FYDLN_acid	<191..268	CDD:302856
		C2H2 Zn finger	330..351	CDD:275368	4/20 (20%)
		C2H2 Zn finger	360..378	CDD:275368	6/17 (35%)
		LIM	361..>400	CDD:295319	13/38 (34%)
		C2H2 Zn finger	386..406	CDD:275368	7/19 (37%)
		zf-C2H2_8	389..465	CDD:292531	21/75 (28%)
		C2H2 Zn finger	417..438	CDD:275368	5/20 (25%)
		C2H2 Zn finger	448..465	CDD:275368	5/16 (31%)
		C2H2 Zn finger	477..498	CDD:275368	8/20 (40%)
		C2H2 Zn finger	511..532	CDD:275368	6/20 (30%)
		C2H2 Zn finger	541..562	CDD:275368	6/20 (30%)
		C2H2 Zn finger	570..590	CDD:275368	8/19 (42%)
		C2H2 Zn finger	598..619	CDD:275368	8/20 (40%)
LOC100537361	XP_003198540.5	C2H2 Zn finger	37..53	CDD:275368
		C2H2 Zn finger	61..81	CDD:275368
		zf-H2C2_2	73..96	CDD:316026
		C2H2 Zn finger	89..109	CDD:275368
		C2H2 Zn finger	117..137	CDD:275368
		COG5048	141..557	CDD:227381
		C2H2 Zn finger	145..165	CDD:275368
		C2H2 Zn finger	173..193	CDD:275368
		C2H2 Zn finger	205..225	CDD:275368
		C2H2 Zn finger	233..253	CDD:275368
		C2H2 Zn finger	261..281	CDD:275368
		C2H2 Zn finger	289..309	CDD:275368
		C2H2 Zn finger	317..337	CDD:275368
		C2H2 Zn finger	345..365	CDD:275368
		C2H2 Zn finger	373..393	CDD:275368
		C2H2 Zn finger	401..421	CDD:275368
		COG5048	425..865	CDD:227381	89/297 (30%)
		C2H2 Zn finger	429..449	CDD:275368
		C2H2 Zn finger	457..477	CDD:275368
		C2H2 Zn finger	485..505	CDD:275368
		C2H2 Zn finger	513..533	CDD:275368
		C2H2 Zn finger	541..561	CDD:275368
		C2H2 Zn finger	569..589	CDD:275368	4/19 (21%)
		C2H2 Zn finger	597..617	CDD:275368	6/19 (32%)
		C2H2 Zn finger	625..645	CDD:275368	7/19 (37%)
		C2H2 Zn finger	653..673	CDD:275368	5/22 (23%)
		C2H2 Zn finger	681..701	CDD:275368	6/20 (30%)
		C2H2 Zn finger	709..729	CDD:275368	8/19 (42%)
		C2H2 Zn finger	737..757	CDD:275368	6/20 (30%)
		C2H2 Zn finger	765..785	CDD:275368	6/20 (30%)
		C2H2 Zn finger	793..813	CDD:275368	8/19 (42%)
		C2H2 Zn finger	821..841	CDD:275368	8/20 (40%)
		C2H2 Zn finger	849..869	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910