DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4282 and LOC100536922

DIOPT Version :9

Sequence 1:	NP_611118.3	Gene:	CG4282 / 36825	FlyBaseID:	FBgn0034114	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	XP_021322225.1	Gene:	LOC100536922 / 100536922	-ID:	-	Length:	1199	Species:	Danio rerio

Alignment Length:	307	Identity:	90/307 - (29%)
Similarity:	137/307 - (44%)	Gaps:	35/307 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   322 KFFTSVLPCAICNLLVHNFT--EMQRHHRLTHQVDPGYMMC-CGRKFTQRKVLAEHVLVHWNPDH 383
            |.||    |:.|.   .|||  |:...|...|..:..|... ||::|.||..|..|:.:|.....
Zfish   806 KPFT----CSECG---QNFTRKEILASHMRIHTGEKPYTCAHCGQRFRQRGNLTAHLRIHNGDKP 863

  Fly   384 FKCSVCEKSFQNSRHLESHQQVHMDPAVKLTFSCDLCSKTFLSKTAIDYHKLNKHV--PKSEFKF 446
            |.|:.||:||.....|.:|.:||..   :..|:|..|.::|..|     ..||.|:  ...:..|
Zfish   864 FACTQCEQSFTRKEILNAHIRVHTG---EKPFTCQQCGQSFTQK-----GNLNSHMRCHNGDKPF 920

  Fly   447 TCSECNKKFLTERKLKNHMSSMHDPESTIICDKCGKQMRTKIILKKHQELMHSDKPRPEPELQQC 511
            .||.|.:.|..:..|..|| .:|..|...:|.:||:..:.:..|:.|....:.:||      ..|
Zfish   921 ACSHCERSFSRKETLDGHM-RVHTGEKPFVCQQCGQSFKLQGNLRVHTRCHNGEKP------FAC 978

  Fly   512 QICGAWLKGMTGLKQHMKSIHVESAGE--HRCHICAKVSPNARALRRHIYHNHECERKFKCTMCE 574
            ..|.........|..|| |:|   .||  ..|..|.:.....|:||.|: .:|..|:.|.|.:||
Zfish   979 TQCERSFSRKETLDGHM-SVH---TGEKPFSCQQCGQSFKQKRSLRAHV-RDHSAEKPFSCELCE 1038

  Fly   575 KAFKRPQELKEHTSTHTGEVLYTCPNCPMTFFCSANMYKHRQRLHRA 621
            |:|.:.:.|:.|..:|||:..:.|..|..:.....|:::| .|:|.|
Zfish  1039 KSFSQKKCLETHLKSHTGDKPFICGQCGKSLKSKVNLFQH-MRIHSA 1084

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071
		FYDLN_acid	<191..268	CDD:302856
		C2H2 Zn finger	330..351	CDD:275368	7/22 (32%)
		C2H2 Zn finger	360..378	CDD:275368	7/18 (39%)
		LIM	361..>400	CDD:295319	14/38 (37%)
		C2H2 Zn finger	386..406	CDD:275368	7/19 (37%)
		zf-C2H2_8	389..465	CDD:292531	22/77 (29%)
		C2H2 Zn finger	417..438	CDD:275368	6/20 (30%)
		C2H2 Zn finger	448..465	CDD:275368	5/16 (31%)
		C2H2 Zn finger	477..498	CDD:275368	5/20 (25%)
		C2H2 Zn finger	511..532	CDD:275368	6/20 (30%)
		C2H2 Zn finger	541..562	CDD:275368	6/20 (30%)
		C2H2 Zn finger	570..590	CDD:275368	7/19 (37%)
		C2H2 Zn finger	598..619	CDD:275368	5/20 (25%)
LOC100536922	XP_021322225.1	C2H2 Zn finger	80..100	CDD:275368
		C2H2 Zn finger	108..128	CDD:275368
		C2H2 Zn finger	136..156	CDD:275368
		zf-C2H2	162..184	CDD:306579
		C2H2 Zn finger	164..184	CDD:275368
		C2H2 Zn finger	192..212	CDD:275368
		C2H2 Zn finger	220..240	CDD:275368
		COG5048	243..642	CDD:227381
		C2H2 Zn finger	248..268	CDD:275368
		C2H2 Zn finger	276..296	CDD:275368
		C2H2 Zn finger	304..324	CDD:275368
		C2H2 Zn finger	332..352	CDD:275368
		C2H2 Zn finger	474..494	CDD:275368
		C2H2 Zn finger	502..522	CDD:275368
		C2H2 Zn finger	530..550	CDD:275368
		C2H2 Zn finger	558..578	CDD:275368
		C2H2 Zn finger	586..606	CDD:275368
		COG5048	610..1046	CDD:227381	78/266 (29%)
		C2H2 Zn finger	614..634	CDD:275368
		C2H2 Zn finger	642..662	CDD:275368
		C2H2 Zn finger	670..690	CDD:275368
		C2H2 Zn finger	698..718	CDD:275368
		C2H2 Zn finger	726..746	CDD:275368
		C2H2 Zn finger	754..774	CDD:275368
		C2H2 Zn finger	782..802	CDD:275368
		C2H2 Zn finger	810..830	CDD:275368	7/22 (32%)
		C2H2 Zn finger	838..858	CDD:275368	7/19 (37%)
		C2H2 Zn finger	866..886	CDD:275368	7/19 (37%)
		C2H2 Zn finger	894..914	CDD:275368	7/24 (29%)
		C2H2 Zn finger	922..942	CDD:275368	7/20 (35%)
		C2H2 Zn finger	950..970	CDD:275368	5/19 (26%)
		C2H2 Zn finger	978..998	CDD:275368	6/20 (30%)
		C2H2 Zn finger	1006..1026	CDD:275368	6/20 (30%)
		C2H2 Zn finger	1034..1054	CDD:275368	7/19 (37%)
		C2H2 Zn finger	1062..1082	CDD:275368	5/20 (25%)
		C2H2 Zn finger	1090..1110	CDD:275368
		C2H2 Zn finger	1118..1138	CDD:275368
		zf-H2C2_2	1131..1155	CDD:316026
		C2H2 Zn finger	1146..1166	CDD:275368
		C2H2 Zn finger	1174..1194	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910