DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4282 and LOC100535286

DIOPT Version :9

Sequence 1:	NP_611118.3	Gene:	CG4282 / 36825	FlyBaseID:	FBgn0034114	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	XP_017210690.1	Gene:	LOC100535286 / 100535286	-ID:	-	Length:	393	Species:	Danio rerio

Alignment Length:	382	Identity:	98/382 - (25%)
Similarity:	152/382 - (39%)	Gaps:	67/382 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   266 ELDNGKQEFAVLPKRTVVRPKKYKKRTKPAEPKVRMSRELLEQRKKQQEEYDVIIAKFFTSVLPC 330
            |:|. ||:|.        :|::.....||...|    :..|.:|.::             |.|.|
Zfish    15 EIDE-KQQFE--------QPQEIMTDEKPTLTK----KTSLNERPRK-------------SKLGC 53

  Fly   331 AI-CNLLVHNFTEMQR---HHRLTHQVDPGYMMCCGRKFTQRKVLAEHVLVHWNPDHFKCSVCEK 391
            .. |.....:|::..:   |.|:..:..|.....||:.|.|.:....|:.:|.....:.|..|.|
Zfish    54 NFSCKQCRKSFSQKPKLDVHMRVHTREQPYTCEQCGKSFGQIQGFKAHMRIHTRERSYTCQQCGK 118

  Fly   392 SFQNSRHLESHQQVHMDPAVKLTFSCDLCSKTFLSKTAIDYHKLNKHVPKSEFKFTCSECNKKFL 456
            ||.::.|..:|.::|..   :..|||..|.|:|..|:.:|.|   ..|...|..:||.:|.|.|.
Zfish   119 SFYHAGHFAAHMRIHTG---EKPFSCKQCGKSFSQKSNLDVH---MRVHTGEKPYTCEQCGKSFS 177

  Fly   457 TERKLKNHMSSMHDPESTIICDKCGKQMRTKIILKKHQELMHSDKP----------RPEPEL--- 508
            .::..|.|| .:|..|.:..|.:|||..|....|..|......:||          ..:|.|
Zfish   178 QKQNFKIHM-RIHTGERSCTCQQCGKSFRHARNLAVHMRTHTGEKPFSCKQCRKSFSKKPNLIAH 241

  Fly   509 ---------QQCQICGAWLKGMTGLKQHMKSIHVESAGE--HRCHICAKVSPNARALRRHIYHNH 562
                     ..|:.||........|..||: ||   .||  :.|..|.|...:...|..|: ..|
Zfish   242 MRVHTREKPYTCEQCGKSFGQKQDLYIHMR-IH---TGEKPYTCTECGKSFAHKSTLNHHM-RTH 301

  Fly   563 ECERKFKCTMCEKAFKRPQELKEHTSTHTGEVLYTCPNCPMTFFCSANMYKHRQRLH 619
            ..|:.|.|..|.|:|.....||.|.:.|||.:::||..|..: ....:..|:..::|
Zfish   302 TGEKPFACAQCGKSFTTKFSLKNHINGHTGTIVFTCDQCGKS-LTRKDSIKNHMKIH 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071
		FYDLN_acid	<191..268	CDD:302856	1/1 (100%)
		C2H2 Zn finger	330..351	CDD:275368	5/24 (21%)
		C2H2 Zn finger	360..378	CDD:275368	5/17 (29%)
		LIM	361..>400	CDD:295319	12/38 (32%)
		C2H2 Zn finger	386..406	CDD:275368	7/19 (37%)
		zf-C2H2_8	389..465	CDD:292531	24/75 (32%)
		C2H2 Zn finger	417..438	CDD:275368	7/20 (35%)
		C2H2 Zn finger	448..465	CDD:275368	5/16 (31%)
		C2H2 Zn finger	477..498	CDD:275368	7/20 (35%)
		C2H2 Zn finger	511..532	CDD:275368	6/20 (30%)
		C2H2 Zn finger	541..562	CDD:275368	5/20 (25%)
		C2H2 Zn finger	570..590	CDD:275368	7/19 (37%)
		C2H2 Zn finger	598..619	CDD:275368	3/20 (15%)
LOC100535286	XP_017210690.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910