DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4282 and zgc:174703

DIOPT Version :9

Sequence 1:	NP_611118.3	Gene:	CG4282 / 36825	FlyBaseID:	FBgn0034114	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	NP_001191325.1	Gene:	zgc:174703 / 100533191	ZFINID:	ZDB-GENE-080208-4	Length:	382	Species:	Danio rerio

Alignment Length:	411	Identity:	98/411 - (23%)
Similarity:	151/411 - (36%)	Gaps:	110/411 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   213 QKPKEDIQLD----LKAEELDEFVD-----EETDPDFSCLVPSDNSSEDDGGSDGFDSDSDFELD 268
            ::..||::::    :|.|:|.|..|     |||    .|     |..|:
Zfish     5 KEESEDVKIEETFTVKQEDLQEQTDLMVLKEET----QC-----NKMEE---------------- 44

  Fly   269 NGKQEFAVLPKRTVVRPKKYKKRTKPAEPKVRMSRELLEQRKKQQEEYDVIIAKFFTSVLPCAIC 333
                              ::::.|...:|.:......|.:.:|.:.|                 |
Zfish    45 ------------------QHQEITADEKPTLTEKTSSLGRPRKSKTE-----------------C 74

  Fly   334 NLLVHNFTEMQRHHRLTHQVDPGYMMCCGRKFTQRKVLAEHVLVHWNPDHFKCSVCEKSFQNSRH 398
                 ||:..||.                :.|.|:..|..|:.||.....:.|..|.|||...|.
Zfish    75 -----NFSSKQRR----------------KSFIQKLNLGVHMRVHTREKPYTCEQCGKSFGKKRS 118

  Fly   399 LESHQQVHMDPAVKLTFSCDLCSKTFLSKTAIDYHKLNKHVPKSEFKFTCSECNKKFLTERKLKN 463
            |::|.::|..   :..::|..|.|:|.....:..|   ..:...|..:||.:|.|.|.....||.
Zfish   119 LKTHMRIHTG---ERPYTCQQCGKSFKQIGTLKGH---MRIHTGERPYTCQQCGKSFKQSATLKG 177

  Fly   464 HMSSMHDPESTIICDKCGKQMRTKIILKKHQELMHSDKPRPEPELQQCQICGAWLKGMTGLKQHM 528
            ||.| |..|....|.:||:..........|:.:...:||      ..||.||...|....||.||
Zfish   178 HMRS-HTGERPYTCQQCGQSFYYAGNFAAHKRIHTGEKP------YTCQQCGKSFKQSGTLKGHM 235

  Fly   529 KSIHVESAGEHRCHICAKVSPNARALRRHIYHNHECERKFKCTMCEKAFKRPQELKEHTSTHTGE 593
            :   :.:.|:.:   |.|.....:.|..|:..:.| |:.:.||.|.|:|.....|..|..|||.|
Zfish   236 R---IHNGGKTQ---CGKSFAQKQKLDTHMTIHTE-EKPYTCTECGKSFTCKSSLINHMKTHTRE 293

  Fly   594 VLYTCPNCPMTFFCSANMYKH 614
            .|:||..|..:|.|.||...|
Zfish   294 KLFTCNQCEKSFTCKANFMNH 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071
		FYDLN_acid	<191..268	CDD:302856	13/63 (21%)
		C2H2 Zn finger	330..351	CDD:275368	5/20 (25%)
		C2H2 Zn finger	360..378	CDD:275368	4/17 (24%)
		LIM	361..>400	CDD:295319	12/38 (32%)
		C2H2 Zn finger	386..406	CDD:275368	8/19 (42%)
		zf-C2H2_8	389..465	CDD:292531	21/75 (28%)
		C2H2 Zn finger	417..438	CDD:275368	5/20 (25%)
		C2H2 Zn finger	448..465	CDD:275368	6/16 (38%)
		C2H2 Zn finger	477..498	CDD:275368	4/20 (20%)
		C2H2 Zn finger	511..532	CDD:275368	9/20 (45%)
		C2H2 Zn finger	541..562	CDD:275368	4/20 (20%)
		C2H2 Zn finger	570..590	CDD:275368	7/19 (37%)
		C2H2 Zn finger	598..619	CDD:275368	7/17 (41%)
zgc:174703	NP_001191325.1	zf-H2C2_2	90..113	CDD:290200	7/22 (32%)
		C2H2 Zn finger	106..126	CDD:275368	8/19 (42%)
		COG5048	<115..361	CDD:227381	64/220 (29%)
		zf-H2C2_2	118..143	CDD:290200	7/27 (26%)
		C2H2 Zn finger	134..154	CDD:275368	5/22 (23%)
		zf-H2C2_2	147..171	CDD:290200	7/26 (27%)
		C2H2 Zn finger	162..182	CDD:275368	9/20 (45%)
		zf-H2C2_2	175..199	CDD:290200	10/24 (42%)
		C2H2 Zn finger	190..210	CDD:275368	4/19 (21%)
		zf-H2C2_2	202..227	CDD:290200	7/30 (23%)
		C2H2 Zn finger	218..238	CDD:275368	9/22 (41%)
		C2H2 Zn finger	243..262	CDD:275368	4/21 (19%)
		zf-H2C2_2	255..279	CDD:290200	9/24 (38%)
		C2H2 Zn finger	270..290	CDD:275368	7/19 (37%)
		C2H2 Zn finger	298..315	CDD:275368	7/17 (41%)
		C2H2 Zn finger	326..346	CDD:275368
		C2H2 Zn finger	354..374	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910