DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4282 and zbtb47

DIOPT Version :9

Sequence 1:	NP_611118.3	Gene:	CG4282 / 36825	FlyBaseID:	FBgn0034114	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	XP_004915642.1	Gene:	zbtb47 / 100489594	XenbaseID:	XB-GENE-992955	Length:	733	Species:	Xenopus tropicalis

Alignment Length:	676	Identity:	151/676 - (22%)
Similarity:	249/676 - (36%)	Gaps:	178/676 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 AMMGDYIDVHSARGDQLEVTTIVNQHFPVQISKESD---ERICGRCWKIVSDFHTLHEFVSAAQS 77
            :|..|.::....|.|   ..|::...|..:|.:|.|   .:|..|   ..:|.:::....|..:.
Frog   145 SMANDILEAEDTRND---TPTVMPPQFYREIKQEVDAPPTKIYAR---EGNDPYSVRVEDSVTKG 203

  Fly    78 SLQETKVALMEDDP---LTQETTSFPEIIKLATQEEEGVTEPQELGGRNFFYPEIKIEEHELD-- 137
            .|..|      ..|   ...|..|...:.|:...:.|...|.||...|.....|:.:....|:
Frog   204 HLPNT------SSPKQYFKDEERSGQRVCKIEGGDSEEDIESQESFNREQIIVEVNLNNQTLNVS 262

  Fly   138 -------TLPRIEILERSANTQENQDQLEGAARRLRKRLKAEDGSSVDKDKDEDGVEETAEPAPP 195
                   :...:.:|:||.......:               |||.. :.:::|.|:||
Frog   263 KGTDGKGSSEPVTVLDRSDGDDRGSE---------------EDGDD-ENEEEEGGLEE------- 304

  Fly   196 KKRRGRPRKSDAAVAPPQKPKEDIQLDLKAEELDEFVDEETDPDFSCLVPSDNSSEDDGGSDGFD 260
                                 ||..||:..:|.||.:..:.|        ::.|.|:|.     |
Frog   305 ---------------------EDDFLDMLEDEEDEGMQSDDD--------NEESREEDR-----D 335

  Fly   261 SDSDFEL---DNGKQEFAVLPKRTVVRPKKYKKRTKPAE-------------PKVRMSRELLEQR 309
            :|...|:   :|..:|.:..|.     ..|..|.||.::             .|.:..::.:.|:
Frog   336 NDETEEIAKDENSAEEESPSPS-----DDKATKLTKGSKGTRNQRGAGGSGRRKKKGGQDGVGQK 395

  Fly   310 KKQQEEYDVIIAKFFTSVLPCAICNLLVHNFTEMQRHHRLTHQVDPGYMMC--CGRKFTQRKVLA 372
            .|.:|:.:          .||..|..:.:|...:::|..:||.   ...:|  ||::|    :|.
Frog   396 GKFEEKQN----------FPCKKCPRVFNNRWYLEKHMNVTHS---RMRICDKCGKRF----LLE 443

  Fly   373 EHVLVHWNPDHFKCSVCEKSFQNSRHLESHQQVHMDPAVKLTFSCDLCSKTFLSKTAIDYHKLNK 437
            ..:::|...|      |||:.|                      |..|.|||  |.....|:.||
Frog   444 SELMLHHQTD------CEKNIQ----------------------CLTCGKTF--KKLWSLHEHNK 478

  Fly   438 HV-PKSEFKFTCSECNKKFLTERKLKNHMSSMHDPESTIICDKCGKQMRTKIILKKHQELMHS-D 500
            .| ..:|.||:|..|.|||.|...::.|:.: |..:....|:.|||..:..:.||.| .|.|| :
Frog   479 IVHGYAEKKFSCDICEKKFYTMAHVRKHLVA-HTKDMPFTCETCGKSFKRSMSLKVH-SLQHSGE 541

  Fly   501 KPRPEPELQQCQICGAWLKGMTGLKQHMKSIHVESAGEHRCHICAKVSPNARALRRHI--YHNHE 563
            ||      .:|:.|....:....|:.|| |||: ...:..|..|.|.....:....|:  :...|
Frog   542 KP------FKCENCHERFQYKYQLRSHM-SIHI-GHKQFMCQWCGKDFNMKQYFDEHMKTHTGKE 598

  Fly   564 CERKFKCTMCEKAFKRPQELKEHTSTHTGEVLYTCPNCPMTFFCSANMYKHRQRLHRAQYEADKN 628
            .|:.|.|.:|.|:|.....:|.|..|||||..|.|..|...|..|..:..||::..:.      .
Frog   599 REKPFICEICGKSFTSRPNMKRHRRTHTGEKPYPCNVCGQRFRFSNMLKAHREKCFQG------G 657

  Fly   629 QP----KPPNILKISRNASTQNKPKQ 650
            .|    .|.....:|.::.:.|.|.|
Frog   658 NPLTPGSPGTAASLSASSQSGNSPGQ 683

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071	14/67 (21%)
		FYDLN_acid	<191..268	CDD:302856	14/79 (18%)
		C2H2 Zn finger	330..351	CDD:275368	4/20 (20%)
		C2H2 Zn finger	360..378	CDD:275368	5/19 (26%)
		LIM	361..>400	CDD:295319	10/38 (26%)
		C2H2 Zn finger	386..406	CDD:275368	4/19 (21%)
		zf-C2H2_8	389..465	CDD:292531	23/76 (30%)
		C2H2 Zn finger	417..438	CDD:275368	8/20 (40%)
		C2H2 Zn finger	448..465	CDD:275368	6/16 (38%)
		C2H2 Zn finger	477..498	CDD:275368	8/20 (40%)
		C2H2 Zn finger	511..532	CDD:275368	6/20 (30%)
		C2H2 Zn finger	541..562	CDD:275368	4/22 (18%)
		C2H2 Zn finger	570..590	CDD:275368	6/19 (32%)
		C2H2 Zn finger	598..619	CDD:275368	6/20 (30%)
zbtb47	XP_004915642.1	BTB_POZ_ZBTB47_ZNF651	29..143	CDD:349540
		2A1904	<216..356	CDD:273344	36/196 (18%)
		CobT2	<309..>359	CDD:226920	15/67 (22%)
		PLN03086	<399..493	CDD:178635	33/140 (24%)
		C2H2 Zn finger	406..427	CDD:275370	4/20 (20%)
		C2H2 Zn finger	433..452	CDD:275368	6/22 (27%)
		C2H2 Zn finger	460..480	CDD:275368	9/21 (43%)
		C2H2 Zn finger	490..510	CDD:275368	7/20 (35%)
		C2H2 Zn finger	518..538	CDD:275368	8/20 (40%)
		SFP1	<540..626	CDD:227516	24/93 (26%)
		C2H2 Zn finger	546..566	CDD:275368	6/20 (30%)
		C2H2 Zn finger	574..594	CDD:275368	4/19 (21%)
		COG5048	601..>650	CDD:227381	17/48 (35%)
		C2H2 Zn finger	605..625	CDD:275368	6/19 (32%)
		C2H2 Zn finger	633..650	CDD:275368	4/16 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910