DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4282 and zfp91

DIOPT Version :9

Sequence 1:	NP_611118.3	Gene:	CG4282 / 36825	FlyBaseID:	FBgn0034114	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	XP_002943167.1	Gene:	zfp91 / 100488073	XenbaseID:	XB-GENE-6000457	Length:	501	Species:	Xenopus tropicalis

Alignment Length:	414	Identity:	100/414 - (24%)
Similarity:	169/414 - (40%)	Gaps:	60/414 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 QSSLQETKVALMEDDPLTQETTSFPEIIKLATQEEEGVTEPQELGGRNFFYPEIKIEEHELDTLP 140
            |..:||.:.:.||::.::::.      :|...:||..|.|.:.    ....|:..:|| |..::.
Frog    58 QQQIQEGRDSYMEENMVSEKA------LKREAEEEVVVQEIEP----TILVPDPPLEE-ESRSIV 111

  Fly   141 RIEILERSANTQENQDQL----EGAARRLRKRLKAEDGSSVDKDKDEDGVEETAEPAPPKKRRGR 201
            |..:|..|...|....||    |.....|...:. |..|......:|:.|..:.|..|.|   ..
Frog   112 RGGVLRSSRTRQTPTLQLICKTEPEPHHLVYEIN-EGPSFTATISEEEDVMISEEEVPYK---DD 172

  Fly   202 PRKSDAAVAPPQKPKEDIQLDLKAEELDEFVDEETD----PDFSCLVPSDNSSEDDGGSDGFDSD 262
            ||..   ...||...||.:.:|.:||...:.|:..|    |......|...........:|...:
Frog   173 PRDE---TYRPQIESEDDEDELISEEEVPYKDDPRDKTYRPQLDREPPRSRRRTSRAKEEGLPVE 234

  Fly   263 SDFELDNGKQEFAVLPKRTVVRPKKYKKRTKPAEPKVRMSRELLEQRKKQQEEYDVIIAKFFTSV 327
            ...|:   |:|..|..:.|   |:|..:|.|..:     |..|.::|||...:|
Frog   235 VKMEV---KEEGQVQEEET---PRKRGRRRKDDK-----SPRLPKRRKKPPIQY----------- 277

  Fly   328 LPCAI--CNLLVHNFTEMQRHHRLTHQVDPGYMMC----CGRKFTQRKVLAEHVLVHWNPDHFKC 386
            :.|.:  |..::.:...:|.|.:..|.:...| :|    |||.|..:|.|..|...|.:...:.|
Frog   278 VRCEMEGCGTVLAHPRYLQHHIKYQHLLKKKY-VCPHPSCGRLFRLQKQLLRHAKHHTDQRDYIC 341

  Fly   387 SVCEKSFQNSRHLESHQQVHMDPAVKLTFSCDLCSKTFLSKTAIDYHKLNKHVPKSEFKFTCSEC 451
            ..|.::|::|.:|..|:.:|..   :....|:.|..|...|.::::| :.||...|.::|:||.|
Frog   342 EYCARAFKSSHNLAVHRMIHTG---EKPLQCEFCGFTCRQKASLNWH-MKKHDADSFYQFSCSIC 402

  Fly   452 NKKFLTERKLKNHMSSMHDPESTI 475
            .|||..:..:..|.:..| ||..|
Frog   403 GKKFEKKDSVVAHKAKSH-PEVLI 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071	1/4 (25%)
		FYDLN_acid	<191..268	CDD:302856	18/80 (23%)
		C2H2 Zn finger	330..351	CDD:275368	4/22 (18%)
		C2H2 Zn finger	360..378	CDD:275368	8/21 (38%)
		LIM	361..>400	CDD:295319	12/38 (32%)
		C2H2 Zn finger	386..406	CDD:275368	6/19 (32%)
		zf-C2H2_8	389..465	CDD:292531	21/75 (28%)
		C2H2 Zn finger	417..438	CDD:275368	5/20 (25%)
		C2H2 Zn finger	448..465	CDD:275368	6/16 (38%)
		C2H2 Zn finger	477..498	CDD:275368
		C2H2 Zn finger	511..532	CDD:275368
		C2H2 Zn finger	541..562	CDD:275368
		C2H2 Zn finger	570..590	CDD:275368
		C2H2 Zn finger	598..619	CDD:275368
zfp91	XP_002943167.1	C2H2 Zn finger	314..333	CDD:275368	7/18 (39%)
		zf-C2H2	339..361	CDD:333835	6/21 (29%)
		C2H2 Zn finger	341..361	CDD:275368	6/19 (32%)
		zf-H2C2_2	353..378	CDD:372612	6/27 (22%)
		C2H2 Zn finger	369..389	CDD:275368	5/20 (25%)
		C2H2 Zn finger	399..415	CDD:275368	6/15 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24403
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100