DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4282 and znf148

DIOPT Version :9

Sequence 1:	NP_611118.3	Gene:	CG4282 / 36825	FlyBaseID:	FBgn0034114	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	XP_031748753.1	Gene:	znf148 / 100487127	XenbaseID:	XB-GENE-996852	Length:	741	Species:	Xenopus tropicalis

Alignment Length:	226	Identity:	46/226 - (20%)
Similarity:	87/226 - (38%)	Gaps:	52/226 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   293 KPAEPKVRMSRELLEQRKKQQEEYDVIIAKFFTSVLPCAICNLLVHNFTEMQRHHRLTHQVDPGY 357
            ||....:..::|:|:.|.:...:.::::.:           ..:.::..||..        .|..
Frog    49 KPLPQGIMAAQEMLQGRDEMMSQDELMVQE-----------ETVKNDEEEMAE--------PPER 94

  Fly   358 MMCCGRKFTQR--------------KVLAEHVLVHWNPDHFKCSVCEKSFQNSRHLESHQQVHMD 408
            ::..|..||.|              |:...||          |..|..:|:.:.||:.|..:|..
Frog    95 ILPQGLHFTVRFPILTINEDGSLGLKIAKCHV----------CEHCNAAFRTNYHLQRHVFIHTG 149

  Fly   409 PAVKLTFSCDLCSKTFLSKTAIDYHKLNKHVPKSEFKFTCSECNKKFLTERKLKNHMSSMHDPES 473
               :..|.|..|...|:.|..:..|   :.:...|..|.|.||..:|:.:..::.|..: |..|.
Frog   150 ---EKPFQCSQCEMRFIQKYLLQRH---EKIHTGEKPFHCDECGMRFIQKYHMERHKRT-HSGEK 207

  Fly   474 TIICDKCGKQM-RTKIILKKHQELMHSDKPR 503
            ...|:.|.:.. ||..:| ||:.:.|.::.|
Frog   208 PYQCEYCLQYFSRTDRVL-KHKRMCHENRER 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071
		FYDLN_acid	<191..268	CDD:302856
		C2H2 Zn finger	330..351	CDD:275368	2/20 (10%)
		C2H2 Zn finger	360..378	CDD:275368	7/31 (23%)
		LIM	361..>400	CDD:295319	11/52 (21%)
		C2H2 Zn finger	386..406	CDD:275368	6/19 (32%)
		zf-C2H2_8	389..465	CDD:292531	18/75 (24%)
		C2H2 Zn finger	417..438	CDD:275368	5/20 (25%)
		C2H2 Zn finger	448..465	CDD:275368	4/16 (25%)
		C2H2 Zn finger	477..498	CDD:275368	7/21 (33%)
		C2H2 Zn finger	511..532	CDD:275368
		C2H2 Zn finger	541..562	CDD:275368
		C2H2 Zn finger	570..590	CDD:275368
		C2H2 Zn finger	598..619	CDD:275368
znf148	XP_031748753.1	zf-C2H2	125..147	CDD:395048	8/31 (26%)
		C2H2 Zn finger	127..147	CDD:275368	6/19 (32%)
		zf-H2C2_2	139..164	CDD:404364	8/27 (30%)
		C2H2 Zn finger	155..175	CDD:275368	5/22 (23%)
		zf-H2C2_2	168..192	CDD:404364	7/26 (27%)
		C2H2 Zn finger	183..203	CDD:275368	5/20 (25%)
		zf-H2C2_2	195..220	CDD:404364	5/25 (20%)
		C2H2 Zn finger	211..229	CDD:275368	7/18 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910