DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4282 and znf1136

DIOPT Version :9

Sequence 1:	NP_611118.3	Gene:	CG4282 / 36825	FlyBaseID:	FBgn0034114	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	XP_017211020.1	Gene:	znf1136 / 100329287	ZFINID:	ZDB-GENE-120709-10	Length:	377	Species:	Danio rerio

Alignment Length:	373	Identity:	98/373 - (26%)
Similarity:	151/373 - (40%)	Gaps:	61/373 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   290 KRTKPAEPKVRMSRELLEQRKKQQEE-------------YDVIIAKFFTSVLPCAICNLLVHNFT 341
            |:..|.|     ..:|:|:.:..:||             .|.|:.|...:...|..|...:....
Zfish    20 KQEDPQE-----QTDLIEENEGSKEEEHHVKIEEKTRLQTDDILKKRDENRFTCTQCGRSLGRKD 79

  Fly   342 EMQRHHRLTHQVDPGYMMCCGRKFTQRKVLAEHVLVHWNPDHFKCSVCEKSFQNSRHLESHQQVH 406
            .::.|.|:.....|.....||:.|.:...|..|:.:|.....|.|:.|.|||::|..|:.|.::|
Zfish    80 NLKIHMRIHTGEKPFTCTQCGKSFNRSSSLNHHMRIHAREKPFTCTQCGKSFRHSLFLKQHMRIH 144

  Fly   407 MDPAVKLTFSCDLCSKTFLSKTAIDYH-----------------------KLNKH--VPKSEFKF 446
            :...   .|:|..|.|:|...::::.|                       ..|:|  :...|..|
Zfish   145 IGDK---PFTCTQCGKSFSQSSSLNRHMRIHTGEKPFTCTRCGKSFSHSSNFNRHMRIHTGEKPF 206

  Fly   447 TCSECNKKFLTERKLKNHMSSMHDPESTIICDKCGKQMRTKIILKKHQELMHSDKPRPEPELQQC 511
            ||::|.|.|.....|.:|| .:|..|....|.:|||.......|..|..:...:||      ..|
Zfish   207 TCTQCEKSFSQSSSLNHHM-RIHTGEKPFTCTQCGKSFSQSSNLNLHMMIHTGEKP------FTC 264

  Fly   512 QICGAWLKGMTGLKQHMKSIHVESAGE--HRCHICAKVSPNARALRRHIYHNHECERKFKCTMCE 574
            ..||......:.|..||: ||   .||  ..|..|.|....:.:|:.|: ..|..|:.|.||.|.
Zfish   265 TQCGKSFSCSSYLNHHMR-IH---TGEKLFSCTQCGKSFSRSLSLKEHM-RIHTGEKPFTCTQCG 324

  Fly   575 KAFKRPQELKEHTSTHTGEVLYTCPNCPMTFFCSANMYKHRQRLHRAQ 622
            |:|.:...|..|..|||||..:||..|..:|..|:|..:| .|:|..:
Zfish   325 KSFSQSSSLNHHMWTHTGEKPFTCTQCGKSFSQSSNFNRH-MRIHTGE 371

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071
		FYDLN_acid	<191..268	CDD:302856
		C2H2 Zn finger	330..351	CDD:275368	4/20 (20%)
		C2H2 Zn finger	360..378	CDD:275368	5/17 (29%)
		LIM	361..>400	CDD:295319	13/38 (34%)
		C2H2 Zn finger	386..406	CDD:275368	8/19 (42%)
		zf-C2H2_8	389..465	CDD:292531	24/100 (24%)
		C2H2 Zn finger	417..438	CDD:275368	6/43 (14%)
		C2H2 Zn finger	448..465	CDD:275368	5/16 (31%)
		C2H2 Zn finger	477..498	CDD:275368	6/20 (30%)
		C2H2 Zn finger	511..532	CDD:275368	6/20 (30%)
		C2H2 Zn finger	541..562	CDD:275368	5/20 (25%)
		C2H2 Zn finger	570..590	CDD:275368	7/19 (37%)
		C2H2 Zn finger	598..619	CDD:275368	7/20 (35%)
znf1136	XP_017211020.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910