DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4282 and si:ch73-40a17.4

DIOPT Version :9

Sequence 1:	NP_611118.3	Gene:	CG4282 / 36825	FlyBaseID:	FBgn0034114	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	XP_005171145.1	Gene:	si:ch73-40a17.4 / 100149710	ZFINID:	ZDB-GENE-131127-71	Length:	408	Species:	Danio rerio

Alignment Length:	433	Identity:	114/433 - (26%)
Similarity:	174/433 - (40%)	Gaps:	59/433 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   209 VAPPQKPKEDIQLDLKAEE---LDEFVDEETDPDFSCLVPSDNSSEDDGGSDGFDSDSDFELDNG 270
            |....:.|.|.:.|  |||   :.|..||..:|:.:.:....|.:.::      .|.|....||.
Zfish     4 VREESEDKSDAEQD--AEEHKGMMEVKDEHKEPEEAEMNEQMNITNEE------QSCSSSRNDNQ 60

  Fly   271 KQEFAVLPKRTVVRPKKYKKRTKPAEPKVRMSRELLEQRKKQQEEYDVI-IAKFFT--------- 325
            ..:.....|.:.:..:..|..|:....::.|.....|:      .|..| ..|.||
Zfish    61 VSQAETQSKHSFICSECGKSFTRRGHLRIHMIIHTGER------PYTCIQCQKSFTCKGSLKDHC 119

  Fly   326 ------SVLPCAICNLLVHNFTEMQRHHRLTHQVDPGYMMCCGRKFTQRKVLAEHVLVHWNPDHF 384
                  ....|..|........:::||.|:.....|.....|.:.||....|..||.:|.....|
Zfish   120 KIHSGEKPFMCPQCGWSFARQEDLKRHIRIHTGEKPFSCAQCTKSFTSSGDLRRHVRIHSGERPF 184

  Fly   385 KCSVCEKSFQNSRHLESHQQVHMDPAVKLTFSCDLCSKTFLSKTAIDYHKLNKHVPKSEFKFTCS 449
            .|:.|:|||.....|:.|.::|....:   |:|.||.|:|..:.::..|   ..|...|....|.
Zfish   185 SCAQCKKSFTQKEGLKEHAKIHSGEKL---FACMLCGKSFTHQRSLKRH---MKVHSGEKLHQCP 243

  Fly   450 ECNKKFLTERKLKNHMSSMHDPESTIICDKCGKQMRTKIILKKHQELMHSDKPRPEPELQQCQIC 514
            ||.::|.....||.|:.| |..|....|:||.|:....:.||.|..: |.|:.|     ..|..|
Zfish   244 ECGRRFAEAGNLKTHLLS-HTGERPFSCEKCEKKFFLAVHLKTHMRI-HEDERR-----YVCSFC 301

  Fly   515 GAWLKGMTGLKQHMKSIHVESAGEHRCHICAK-----VSPNARALRRHIYHNHECERKFKCTMCE 574
            |.....:.|.|.|.|: |:   || :.::|.:     :.|....:...|   |..|:.:||:.||
Zfish   302 GKSFLWLNGFKDHQKT-HI---GE-KPYVCLECGSTFIRPGELKVHERI---HTGEKPYKCSHCE 358

  Fly   575 KAFKRPQELKEHTSTHTGEVLYTCPNCPMTFFCSANMYKHRQR 617
            |:|.:...||.|...||||..|.||.|..||....|:.||.::
Zfish   359 KSFTQSGALKIHKRVHTGEKPYLCPTCGKTFSRYGNLGKHLKK 401

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071
		FYDLN_acid	<191..268	CDD:302856	14/61 (23%)
		C2H2 Zn finger	330..351	CDD:275368	5/20 (25%)
		C2H2 Zn finger	360..378	CDD:275368	6/17 (35%)
		LIM	361..>400	CDD:295319	13/38 (34%)
		C2H2 Zn finger	386..406	CDD:275368	7/19 (37%)
		zf-C2H2_8	389..465	CDD:292531	22/75 (29%)
		C2H2 Zn finger	417..438	CDD:275368	6/20 (30%)
		C2H2 Zn finger	448..465	CDD:275368	6/16 (38%)
		C2H2 Zn finger	477..498	CDD:275368	7/20 (35%)
		C2H2 Zn finger	511..532	CDD:275368	7/20 (35%)
		C2H2 Zn finger	541..562	CDD:275368	3/25 (12%)
		C2H2 Zn finger	570..590	CDD:275368	8/19 (42%)
		C2H2 Zn finger	598..619	CDD:275368	8/20 (40%)
si:ch73-40a17.4	XP_005171145.1	COG5048	<40..193	CDD:227381	32/164 (20%)
		C2H2 Zn finger	74..94	CDD:275368	3/19 (16%)
		zf-H2C2_2	86..111	CDD:290200	6/30 (20%)
		C2H2 Zn finger	102..122	CDD:275368	4/19 (21%)
		C2H2 Zn finger	130..150	CDD:275368	5/19 (26%)
		zf-H2C2_2	142..167	CDD:290200	6/24 (25%)
		zf-C2H2_8	155..235	CDD:292531	25/85 (29%)
		C2H2 Zn finger	158..178	CDD:275368	6/19 (32%)
		zf-H2C2_2	170..195	CDD:290200	10/24 (42%)
		C2H2 Zn finger	186..206	CDD:275368	7/19 (37%)
		C2H2 Zn finger	214..234	CDD:275368	6/22 (27%)
		zf-H2C2_2	226..250	CDD:290200	6/26 (23%)
		C2H2 Zn finger	242..262	CDD:275368	8/20 (40%)
		C2H2 Zn finger	270..290	CDD:275368	7/20 (35%)
		C2H2 Zn finger	298..318	CDD:275368	7/20 (35%)
		C2H2 Zn finger	326..346	CDD:275368	3/22 (14%)
		zf-H2C2_2	338..363	CDD:290200	9/27 (33%)
		C2H2 Zn finger	354..374	CDD:275368	8/19 (42%)
		zf-H2C2_2	366..391	CDD:290200	13/24 (54%)
		C2H2 Zn finger	382..400	CDD:275368	8/17 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910