DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4282 and sall1

DIOPT Version :9

Sequence 1:	NP_611118.3	Gene:	CG4282 / 36825	FlyBaseID:	FBgn0034114	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	NP_001090646.1	Gene:	sall1 / 100036618	XenbaseID:	XB-GENE-491393	Length:	1330	Species:	Xenopus tropicalis

Alignment Length:	664	Identity:	114/664 - (17%)
Similarity:	179/664 - (26%)	Gaps:	318/664 - (47%)

- Green bases have known domain annotations that are detailed below.

  Fly   188 ETAEPAP-----PKKRRGRPRKSDAAVAPPQKPKEDIQLDLKAEE--LDEFVDEETDPDFSCLVP 245
            :|.||.|     |........||:.|..|..|...|:..:.:|..  ||:  :|:...:..|:..
Frog   584 KTEEPQPIAISHPTASPPDSVKSETATEPLLKKTSDLPDEAEAAMPILDK--EEQQSQNSDCIQN 646

  Fly   246 SDNSSEDDGGSDGFDSDSDFELDNGKQEFAVLPKRTVVRPKKYKKR--------TKPAEPKVRMS 302
            .:.|:.......|..:.....|         ||    :..:::|.:        ..||....::
Frog   647 LNTSACSPTTGSGISASFPNPL---------LP----LMSEQFKAKFPFGGLLDVAPASETSKL- 697

  Fly   303 RELLEQRKKQQEEYDVIIAKFFTSVLPCAICNLLVHNFTEMQRHHRLTHQVD-PGYMMCCGRKFT 366
            ::|:|...|:..:.:           .|.||..::...:.::.|:| ||..: |.....|||.||
Frog   698 QQLVENIDKKSSDPN-----------ECVICRRVLSCQSALKMHYR-THTGERPFKCKICGRAFT 750

  Fly   367 QRKVLAEHVLVH-----WNPDHFKCSVCEKSFQNSRHLESHQQVHM------------------- 407
            .:..|..|..||     ....| .|.:|:|.|.|:..|:.|.::||
Frog   751 TKGNLKTHYSVHRAMPPLRVQH-SCPICQKKFTNAVVLQQHIRMHMGGQIPNTPIAESYPDSMES 814

  Fly   408 ----------------------------------------------------------------- 407

Frog   815 DTGSFDEKTIDDLDNFSDENMEDCPDSSVPDTPKSVDASQDSLSSSPLPPEVSSITALENQMKLI 879

  Fly   408 ----------------------------------------------------------------- 407

Frog   880 NAGLAEQLQASLKSTENGSIEGDGMTNDSSSLGGDMESQSAGSPAASESTYSMHALSPSNSTNDY 944

  Fly   408 ----------------DP------------AVKLTFS---------------------------C 417
                            ||            |:.||.|                           |
Frog   945 LKSPNTDEKIHRALSLDPTSGLSPTPANGGALDLTSSNTDKVIKDEHLGVLFPFRERGKYKNTIC 1009

  Fly   418 DLCSKTFLSKTAIDYHKLNKHVPKSEFKFTCSECNKKFLTERKLKNHM---------SSMHDPES 473
            |:|.|||..::|:|.| ...|.  .|..|.|:.||:.|.|:..||.||         |.:.:|.|
Frog  1010 DICGKTFACQSALDIH-YRSHT--KERPFICTVCNRGFSTKGNLKQHMLTHQMRDLPSQLFEPSS 1071

  Fly   474 TIICDKCGKQMRTK----IILKKHQELMHSDKPRPEPELQQCQICGAWLKGMTGLKQHMKS--IH 532
            ::..........|.    ||..:....||                        |..|.:|.  .:
Frog  1072 SMTPTPTVPSTPTNPLATIIKTEFNGFMH------------------------GSSQDIKEQPTN 1112

  Fly   533 VESAG---------------------EHRCHICAKVSPNARALRRHIYHNHECERKFKCTMCEKA 576
            :.|:|                     :|.|:.|.|...::.||:.| ...|..|:.|.||:|.:|
Frog  1113 IVSSGSLPSSATSPVLLPALARRTPKQHYCNACGKSFSSSSALQIH-ERTHTGEKPFACTICGRA 1176

  Fly   577 FKRPQELKEHTSTH 590
            |.....||.|..||
Frog  1177 FTTKGNLKVHMGTH 1190

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071
		FYDLN_acid	<191..268	CDD:302856	17/83 (20%)
		C2H2 Zn finger	330..351	CDD:275368	5/20 (25%)
		C2H2 Zn finger	360..378	CDD:275368	7/17 (41%)
		LIM	361..>400	CDD:295319	15/43 (35%)
		C2H2 Zn finger	386..406	CDD:275368	7/19 (37%)
		zf-C2H2_8	389..465	CDD:292531	33/279 (12%)
		C2H2 Zn finger	417..438	CDD:275368	9/20 (45%)
		C2H2 Zn finger	448..465	CDD:275368	7/16 (44%)
		C2H2 Zn finger	477..498	CDD:275368	3/24 (13%)
		C2H2 Zn finger	511..532	CDD:275368	3/22 (14%)
		C2H2 Zn finger	541..562	CDD:275368	6/20 (30%)
		C2H2 Zn finger	570..590	CDD:275368	8/19 (42%)
		C2H2 Zn finger	598..619	CDD:275368
sall1	NP_001090646.1	PHA03247	<278..683	CDD:223021	22/113 (19%)
		PRK10856	<326..>438	CDD:236776
		SUF4-like	461..543	CDD:411020
		C2H2 Zn finger	464..485	CDD:411020
		C2H2 Zn finger	464..484	CDD:275368
		C2H2 Zn finger	492..512	CDD:411020
		C2H2 Zn finger	492..512	CDD:275368
		C2H2 Zn finger	714..734	CDD:275368	5/20 (25%)
		zf-H2C2_2	726..751	CDD:404364	9/25 (36%)
		C2H2 Zn finger	742..762	CDD:275368	7/19 (37%)
		zf-C2H2	772..794	CDD:395048	8/22 (36%)
		C2H2 Zn finger	774..794	CDD:275368	7/19 (37%)
		C2H2 Zn finger	1009..1029	CDD:275370	9/20 (45%)
		SUF4-like	1012..>1056	CDD:411020	19/46 (41%)
		C2H2 Zn finger	1012..1030	CDD:411020	7/18 (39%)
		zf-C2H2	1035..1057	CDD:395048	10/21 (48%)
		C2H2 Zn finger	1037..1057	CDD:275370	9/19 (47%)
		C2H2 Zn finger	1037..1056	CDD:411020	9/18 (50%)
		SUF4-like	1140..>1187	CDD:411020	17/47 (36%)
		C2H2 Zn finger	1142..1163	CDD:411020	6/21 (29%)
		C2H2 Zn finger	1142..1162	CDD:275368	6/20 (30%)
		C2H2 Zn finger	1170..1190	CDD:275368	8/19 (42%)
		C2H2 Zn finger	1170..1187	CDD:411020	7/16 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910