DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4282 and si:ch73-367f21.6

DIOPT Version :9

Sequence 1:	NP_611118.3	Gene:	CG4282 / 36825	FlyBaseID:	FBgn0034114	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	XP_017207864.1	Gene:	si:ch73-367f21.6 / 100005030	ZFINID:	ZDB-GENE-120214-31	Length:	488	Species:	Danio rerio

Alignment Length:	401	Identity:	102/401 - (25%)
Similarity:	153/401 - (38%)	Gaps:	105/401 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   334 NLLVHN------FTEMQR-----------HHRLTHQVDPGY-MMCCGRKFTQRKVLAEHVLVHWN 380
            :|.:|.      ||..||           .|.:.|..|..: .:.||:.||||:.|..|:.:|..
Zfish    23 SLKIHTGESGEPFTCKQRGEILTTNQSLESHTVIHTGDQNFNCVVCGKSFTQRRYLKNHMKIHTG 87

  Fly   381 PDHFKCSVCEKSFQNSRHLESHQQVHM--DPAV-----------------------KLTFSCDLC 420
            ...|.|..|:|.|...:.||:|.::|.  .|.:                       :..::|..|
Zfish    88 DHPFTCPECDKCFTVKQSLETHLKIHTGEKPFICPDCGKKFRIKHSLEGHMRIHTGEKPYTCQEC 152

  Fly   421 SKTFLSKTAIDYHK-----------------------LNKHVP--KSEFKFTCSECNKKFLTERK 460
            .|.|..|..:|.|.                       |..|:.  ..|..:||.||.|.|..::.
Zfish   153 GKRFTEKQTLDKHLTIHTGEKPYSCPECGKSFRVKFCLENHIKIHTGEKPYTCQECGKSFTEKQN 217

  Fly   461 LKNHMSSMHDPESTIICDKCGKQMRTKIILKKHQELMHSDKPRPEPELQQ--------------- 510
            |:.|| .:|..|....|.:||:..|.|..||.|..:...:||.   ..||
Zfish   218 LERHM-RIHTGEKPFACPECGRSFRVKQDLKSHVRIHTGEKPF---SCQQCGKSFSENKTLESHM 278

  Fly   511 ----------CQICGAWLKGMTGLKQHMKSIHVESAGEHR--CHICAKVSPNARALRRHIYHNHE 563
                      |..||...:|...|:.||: :|   .||.|  |..|.|.....::|:.|| ..|.
Zfish   279 RIHTGEKPFVCSHCGRRFRGKQNLESHMR-LH---TGEKRYTCPQCGKSYNEQKSLQIHI-RTHT 338

  Fly   564 CERKFKCTMCEKAFKRPQELKEHTSTHTGEVLYTCPNCPMTFFCSANMYKHRQRLHRAQYEADKN 628
            .|:.|.|..|.|:|::...|:.|...||||..:|||.|..:|.....:.:|: ::|..:...|.:
Zfish   339 GEKPFACDECGKSFRQQSTLRGHIKIHTGEKPFTCPQCGKSFIEKTKLERHK-KIHSGEKPFDCH 402

  Fly   629 QPKPPNILKIS 639
            ..|....:|.|
Zfish   403 HCKKSFTMKQS 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071
		FYDLN_acid	<191..268	CDD:302856
		C2H2 Zn finger	330..351	CDD:275368	7/33 (21%)
		C2H2 Zn finger	360..378	CDD:275368	8/17 (47%)
		LIM	361..>400	CDD:295319	14/38 (37%)
		C2H2 Zn finger	386..406	CDD:275368	7/19 (37%)
		zf-C2H2_8	389..465	CDD:292531	25/125 (20%)
		C2H2 Zn finger	417..438	CDD:275368	8/43 (19%)
		C2H2 Zn finger	448..465	CDD:275368	6/16 (38%)
		C2H2 Zn finger	477..498	CDD:275368	8/20 (40%)
		C2H2 Zn finger	511..532	CDD:275368	7/20 (35%)
		C2H2 Zn finger	541..562	CDD:275368	6/20 (30%)
		C2H2 Zn finger	570..590	CDD:275368	6/19 (32%)
		C2H2 Zn finger	598..619	CDD:275368	5/20 (25%)
si:ch73-367f21.6	XP_017207864.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910