DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG8060 and RCCD1

DIOPT Version :9

Sequence 1:NP_611117.2 Gene:CG8060 / 36824 FlyBaseID:FBgn0034113 Length:1189 Species:Drosophila melanogaster
Sequence 2:NP_001017919.1 Gene:RCCD1 / 91433 HGNCID:30457 Length:376 Species:Homo sapiens


Alignment Length:235 Identity:56/235 - (23%)
Similarity:96/235 - (40%) Gaps:47/235 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   169 TPQAVDFFR--KSNLWLEQVALGAYHSLFCDKKGHLYAVGHGKGGRLGIGLENSLPAPKRVKVSS 231
            :|:| .|:|  ...|...|:.|||.|:|..|..|.:::.|.|:.|:||.|   :|.|....::..
Human   145 SPRA-PFYRPLAPELRARQLELGAEHALLLDAAGQVFSWGGGRHGQLGHG---TLEAELEPRLLE 205

  Fly   232 KLSGDSIQCISVSRQHSLVLTHQSLVFACGLNTDHQLGV--RDAAEQ-LTQFKEVVALRDKGA-- 291
            .|.|..:..::....||:.::....::..|.|...||.:  |:.||. .|..:|...|.:.|:  
Human   206 ALQGLVMAEVAAGGWHSVCVSETGDIYIWGWNESGQLALPTRNLAEDGETVAREATELNEDGSQV 270

  Fly   292 -----------------------------SDLVRVIACDQHSIAYGSRC--VYVWG-ANQGQFGI 324
                                         ||.|:. :|.....|..:|.  :|.|| ...||.| 
Human   271 KRTGGAEDGAPAPFIAVQPFPALLDLPMGSDAVKA-SCGSRHTAVVTRTGELYTWGWGKYGQLG- 333

  Fly   325 NSNTPSITVPTLIK--LPAKTTIRFVEANNAATVIYNEEK 362
            :.:|.|:..|..::  :..:..::.|......|.:|..||
Human   334 HEDTTSLDRPRRVEYFVDKQLQVKAVTCGPWNTYVYAVEK 373

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8060NP_611117.2 ANK <46..138 CDD:238125
ANK repeat 56..87 CDD:293786
Ank_4 57..111 CDD:290365
ANK repeat 89..121 CDD:293786
Ank_2 95..>138 CDD:289560
RCC1 147..195 CDD:278826 10/27 (37%)
RCC1 199..251 CDD:278826 13/51 (25%)
BTB 547..>635 CDD:295341
BTB 684..795 CDD:279045
BTB 697..798 CDD:197585
SPOP_C_like 798..>834 CDD:269810
RCCD1NP_001017919.1 Interaction with KDM8. /evidence=ECO:0000269|PubMed:24981860 1..169 9/24 (38%)
ATS1 <156..340 CDD:227511 45/188 (24%)
RCC1 2 176..227 13/53 (25%)
RCC1 3 229..317 16/88 (18%)
RCC1 4 318..371 12/53 (23%)
RCC1 319..366 CDD:395335 10/47 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5184
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.