DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8060 and ATS1

DIOPT Version :9

Sequence 1:	NP_611117.2	Gene:	CG8060 / 36824	FlyBaseID:	FBgn0034113	Length:	1189	Species:	Drosophila melanogaster
Sequence 2:	NP_009382.2	Gene:	ATS1 / 851213	SGDID:	S000000018	Length:	333	Species:	Saccharomyces cerevisiae

Alignment Length:	229	Identity:	50/229 - (21%)
Similarity:	82/229 - (35%)	Gaps:	51/229 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   148 VLVWGSNKNYNLGIGNEQNTNTPQ--------AVDFFRKSNLWLEQVALGAYHSLFCDKKGHLYA 204
            |..:|||....||:|::::.:|||        |:         :.::|.|..||:.....|:|..
Yeast     4 VYAFGSNGQRQLGLGHDEDMDTPQRSVPGDDGAI---------VRKIACGGNHSVMLTNDGNLVG 59

  Fly   205 VGHGKGGRLGIGLENSLPAPKRVKVSSKLSGDSIQCISVSRQHSLVLTHQSLV-FACGLNT---- 264
            .|..:.|.|                      ||.|.:........|.....:| .|||.:|
Yeast    60 CGDNRRGEL----------------------DSAQALRQVHDWRPVEVPAPVVDVACGWDTTVIV 102

  Fly   265 --DHQLGVR-DAAEQLTQFKEVVALRDKGASDLVRVIACDQHSIAYGSRCVYVWGANQGQFGINS 326
              |.::..| ....:.||  :.|.|...  .:.:.|..|.|:.:......||.||:|........
Yeast   103 DADGRVWQRGGGCYEFTQ--QHVPLNSN--DERIAVYGCFQNFVVVQGTRVYGWGSNTKCQLQEP 163

  Fly   327 NTPSITVPTLIKLPAKTTIRFVEANNAATVIYNE 360
            .:.|:..|.|:.......:.:|.......||.:|
Yeast   164 KSRSLKEPVLVYDTGSVAVDYVAMGKDFMVIVDE 197

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8060	NP_611117.2	ANK	<46..138	CDD:238125
		ANK repeat	56..87	CDD:293786
		Ank_4	57..111	CDD:290365
		ANK repeat	89..121	CDD:293786
		Ank_2	95..>138	CDD:289560
		RCC1	147..195	CDD:278826	15/54 (28%)
		RCC1	199..251	CDD:278826	8/51 (16%)
		BTB	547..>635	CDD:295341
		BTB	684..795	CDD:279045
		BTB	697..798	CDD:197585
		SPOP_C_like	798..>834	CDD:269810
ATS1	NP_009382.2	ATS1	1..333	CDD:227511	50/229 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900