DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8060 and Rcc1

DIOPT Version :9

Sequence 1:	NP_611117.2	Gene:	CG8060 / 36824	FlyBaseID:	FBgn0034113	Length:	1189	Species:	Drosophila melanogaster
Sequence 2:	XP_006239135.1	Gene:	Rcc1 / 682908	RGDID:	1592835	Length:	434	Species:	Rattus norvegicus

Alignment Length:	240	Identity:	56/240 - (23%)
Similarity:	92/240 - (38%)	Gaps:	47/240 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   136 DDDDLATDSQNDVLVWGSNKNYNLGIGNEQNTNTPQAVDFFRKSNLWLE--------QVALGAYH 192
            |....|......|.:|||.::.|..||         .::..:||.:.::        :||.|..|
  Rat   141 DSHTAALTEDGRVFLWGSFRDNNGVIG---------LLEPMKKSMVPVQVQLDTQVVKVASGNDH 196

  Fly   193 SLFCDKKGHLYAVGHGKGGRLG------------IGLENSLPAPKRVKVSSKLSGDSI--QCISV 243
            .:.....|.||.:|.|:.|:||            .|||..| .|:.|.:.|:.:...:  |....
  Rat   197 LVMLTTDGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLL-VPRCVLLKSRGTRGRVRFQDAFC 260

  Fly   244 SRQHSLVLTHQSLVFACGLNTDHQLGVRDAA-----EQLTQFKEVVALRDKGASDLVRVIACDQH 303
            ....:..::.:..|:..||:..||||.....     :.||.||       ......|.......|
  Rat   261 GAYFTFAISREGHVYGFGLSNYHQLGTPGTGSCFIPQNLTSFK-------NSTKSWVGFSGGQHH 318

  Fly   304 SIAYGSR-CVYVWG-ANQGQFGINSNTPSITVPTLI-KLPAKTTI 345
            ::...|. ..|..| |..|:.|:.......::|||| :||..:::
  Rat   319 TVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPVVSSV 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8060	NP_611117.2	ANK	<46..138	CDD:238125	1/1 (100%)
		ANK repeat	56..87	CDD:293786
		Ank_4	57..111	CDD:290365
		ANK repeat	89..121	CDD:293786
		Ank_2	95..>138	CDD:289560	1/1 (100%)
		RCC1	147..195	CDD:278826	13/55 (24%)
		RCC1	199..251	CDD:278826	16/65 (25%)
		BTB	547..>635	CDD:295341
		BTB	684..795	CDD:279045
		BTB	697..798	CDD:197585
		SPOP_C_like	798..>834	CDD:269810
Rcc1	XP_006239135.1	ATS1	19..432	CDD:227511	56/240 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900