DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8060 and rcc1

DIOPT Version :9

Sequence 1:	NP_611117.2	Gene:	CG8060 / 36824	FlyBaseID:	FBgn0034113	Length:	1189	Species:	Drosophila melanogaster
Sequence 2:	NP_998343.1	Gene:	rcc1 / 406457	ZFINID:	ZDB-GENE-040426-2216	Length:	418	Species:	Danio rerio

Alignment Length:	182	Identity:	51/182 - (28%)
Similarity:	85/182 - (46%)	Gaps:	33/182 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   198 KKGHLYAVGHGKGGRLGIG---LENSLPA----PKRVKVSSKLSGDSIQCISVSRQHSLVLTHQS 255
            :||.:..:|.|..|:||:|   :|...||    |:.:          :|.:: ...|::.|:...
Zfish    33 EKGLVLVLGQGDVGQLGLGEDVMERKKPALVTLPEGI----------VQAVA-GGMHTVCLSDTG 86

  Fly   256 LVFACGLNTDHQLGVRDAAEQLTQFKEVVALRDKGASDLVRVIACDQHSIAY---GSRCVYVWGA 317
            .|:..|.|.:..|| ||.:|:.::  .|.|..|.| ..:::|.|.|.||.|.   |.  |||||:
Zfish    87 NVYTFGCNDEGALG-RDTSEEGSE--TVPAKVDLG-EKIIQVSAGDSHSAALTEDGG--VYVWGS 145

  Fly   318 ---NQGQFGINSNTPSITVPTLIKLPA-KTTIRFVEANNAATVIYNEEKIIT 365
               |.|..|:.......|||  :|:|. |..::.|..|:...::....::.|
Zfish   146 FRDNNGVIGLLEPMKKCTVP--VKVPIDKPVVKIVSGNDHLVMLTAHGELYT 195

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8060	NP_611117.2	ANK	<46..138	CDD:238125
		ANK repeat	56..87	CDD:293786
		Ank_4	57..111	CDD:290365
		ANK repeat	89..121	CDD:293786
		Ank_2	95..>138	CDD:289560
		RCC1	147..195	CDD:278826
		RCC1	199..251	CDD:278826	14/58 (24%)
		BTB	547..>635	CDD:295341
		BTB	684..795	CDD:279045
		BTB	697..798	CDD:197585
		SPOP_C_like	798..>834	CDD:269810
rcc1	NP_998343.1	ATS1	3..415	CDD:227511	51/182 (28%)
		RCC1	34..82	CDD:278826	14/58 (24%)
		RCC1	86..134	CDD:278826	17/51 (33%)
		RCC1	137..187	CDD:278826	17/53 (32%)
		RCC1	191..252	CDD:278826	1/5 (20%)
		RCC1	255..306	CDD:278826
		RCC1	309..357	CDD:278826
		RCC1	361..411	CDD:278826
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900