Protein Alignment CG8060 and Rcbtb1

DIOPT Version :10

• Sequence 1: NP_611117.2
• Gene: CG8060 / 36824
• FlyBaseID: FBgn0034113
• Length: 1189
• Species: Drosophila melanogaster
• Sequence 2: NP_001101850.1
• Gene: Rcbtb1 / 361050
• RGDID: 1308467
• Length: 531
• Species: Rattus norvegicus
• Alignment Length: 725
• Identity: 144/725 - (19%)
• Similarity: 221/725 - (30%)
• Gaps: 263/725 - (36%)

  Fly   142 TDSQNDVLVWGSNKNYNLGIGNEQNTNTPQAVDFFRKSNLWLEQVALGA-YHSLFCDKKGHLYAV 205
            ||| ::|.|:|.|.:..||.|:.|:|..|:.::......  ::.::.|: .|.|...:.|.:||.
  Rat    38 TDS-DEVFVFGLNYSNCLGTGDNQSTLVPKKLEALCGKR--IKSLSYGSGPHVLLSTEDGVVYAW 99

  Fly   206 GHGKGGRLGIGLENSLPAPKRVKVSSKLSGDSIQCISVSRQHSLVLTHQSLVFACGLNTDHQLGV 270
            ||....:||.|..|...||  ::|.:.|....:..::....||:.|.....:||.|.|...|:|.
  Rat   100 GHNGYSQLGNGTTNQGIAP--IQVCTNLLVKQVVEVACGSHHSMALAADGELFAWGYNNCGQVGS 162

  Fly   271 RDAAEQLTQFKEVVALRDKGASDLVRVIACDQHS--IAYGSRCVYVWGAN-QGQFGINSNTPSIT 332
            ...|.|.|..|....|..|...:    |||.|.|  ....|..||.||.| .||.|:.:|...:|
  Rat   163 GSTANQPTPRKVTNCLHTKKVVN----IACGQTSSMAVLDSGEVYGWGYNGNGQLGLGNNGNQLT 223

  Fly   333 VPTLIKLPAKTTIRFVEANNAATVIYNEEKIITLCYADKTRYIKTPNYEDLKSISVMGGNLKNST 397
            ...:..|..              |..|:   |...||
  Rat   224 PVRVAALHG--------------VCVNQ---IVCGYA---------------------------- 243

  Fly   398 KGSAAALKLLMLTETNVVYLWYENTQQFYRCNFSPIRLHQIKKILYKCNQVMVLSEDGCVYRGKC 462
                   ..|.||:..::|.|..||.                               |.:..|..
  Rat   244 -------HTLALTDEGLLYAWGANTY-------------------------------GQLGTGSK 270

  Fly   463 NQIALPSSALQEKSRGSLDNWQDNDQNKTEISREHVIRIELQRVPNIDRATYIFCDEGFSSFAVL 527
            |.:..|:..:.||                    |.||
  Rat   271 NNLLSPTQIMVEK--------------------ERVI---------------------------- 287

  Fly   528 QESHTKYFRKPSLPRREHSFKKLLHETSDCDAVHDVVFHVDGEKFAAHKFIIYSRAPGLRDLIRC 592
                                     |.:.|.:.|.......|
  Rat   288 -------------------------EIAACHSTHTSAAKTQG----------------------- 304

  Fly   593 YLDKDIYLNFDHLTGKMFELILNHIYSSYWPTEDDIDCIQQSLGPANPQQRTRTCEMFLPHLEKF 657
                                  .|:|  .|.     .|..||              :.||||..|
  Rat   305 ----------------------GHVY--MWG-----QCRGQS--------------VILPHLTHF 326

  Fly   658 QLVE----------LTKYVQSYVRDHQFPLPNARKLFNRLYRSDHPELYDVRIVCKDGKVLGAHK 712
            ...:          ::..:.|.  :|:..|..|..|....   |.||..|::... |||.:..||
  Rat   327 SCTDDVFACFGTPAVSWRLLSV--EHEDFLTVAESLKKEF---DSPETADLKFRI-DGKYIHVHK 385

  Fly   713 CMLVARLEYFEMMFMHLWAERSSVTMEGVPAEYMEPV----LDYLYSLDNEAFCKQGYLETFLYN 773
            .:|..|.|:|..||...|.|.....:|  ..::..||    |.|||: |......:..:     .
  Rat   386 AVLKIRCEHFRSMFQSYWNEDMKEVIE--IDQFSYPVYRAFLQYLYT-DTVDLPPEDAI-----G 442

  Fly   774 MITICDQYFIESLQNVCESLILDKISIRKCGEMLEFAAMYNCKILQKGCMDFICQNLSRVLCYRS 838
            ::.:...|....|:.:|:.:|...|::.....:...|..|:.:.|::.|..|...:|:.|....:
  Rat   443 LLDLATSYCENRLKRLCQHIIKRGITVENAFSLFSAAVRYDAEDLEEFCFKFCINHLTEVTQTAA 507

  Fly   839 IEQCDGETLK 848
            ..|.||..||
  Rat   508 FWQMDGPLLK 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8060	NP_611117.2	ANKYR	<51..141	CDD:440430
		ANK repeat	56..87	CDD:293786
		ANK repeat	89..121	CDD:293786
		ATS1	140..>355	CDD:444065	61/216 (28%)
		BTB_POZ	543..643	CDD:453885	10/99 (10%)
		BTB2_POZ_IBtk	691..802	CDD:349611	30/114 (26%)
		BACK_IBtk	798..857	CDD:350575	13/51 (25%)
Rcbtb1	NP_001101850.1	ATS1	37..311	CDD:444065	88/484 (18%)
		BTB_POZ_RCBTB1_CLLD7	350..466	CDD:349662	33/127 (26%)
		BACK_RCBTB1	466..531	CDD:350603	13/52 (25%)