Protein Alignment CG8060 and Ibtk

DIOPT Version :10

• Sequence 1: NP_611117.2
• Gene: CG8060 / 36824
• FlyBaseID: FBgn0034113
• Length: 1189
• Species: Drosophila melanogaster
• Sequence 2: NP_001414686.1
• Gene: Ibtk / 315858
• RGDID: 1311697
• Length: 1352
• Species: Rattus norvegicus
• Alignment Length: 1384
• Identity: 363/1384 - (26%)
• Similarity: 587/1384 - (42%)
• Gaps: 273/1384 - (19%)

  Fly    10 DCTAKCRLRQHGNAITAALTKRSIDNQKLASFIFKTCGNFANILDDLGRSAVHMSASTARYEILE 74
            |||||||..:|...:.:.:||.|  .:::..|:...|.|.|.:.|..||:|:|:.:|..:..:|:
  Rat     7 DCTAKCRSLKHALDVLSVITKGS--ERQIKIFLSSYCYNAATVKDAFGRNALHLVSSCGKKAVLD 69

  Fly    75 WLLNHGAYINGQDYESGSSPLHRALYYGSIDCAVLLLRYGASLELLDEDTRCPLQAICRKCDDDD 139
            ||:..|..:..:|.|||.:.|||:::||.|:|...||::|.||.:.|::...||..:.:    |.
  Rat    70 WLIEKGVDLLVKDKESGWTALHRSIFYGHINCVWSLLKHGVSLYMQDKEGLSPLDLLMK----DR 130

  Fly   140 LA------TDSQNDVLVWGSNKNYNLGIGNEQNTNTPQAVDFFRKSNLWLEQVALGAYHSLFCDK 198
            .|      || ..:|..||.|.|:.||.|::.:.:.|:.:|.|.:|.::::||.|..:||:|..:
  Rat   131 PAHVVFKNTD-PTEVYTWGDNTNFTLGHGSQNSKHHPELLDLFSRSRVYVKQVVLCKFHSVFLSQ 194

  Fly   199 KGHLYAVGHGKGGRLGIGLENSLPAPKRVKVSSKLSGDSIQCISVSRQHSLVLTHQSLVFACGLN 263
            :|.:|..|||:|||||.|.|.:...|:.|:   .|||.|...::.::.|::|||....|:..|||
  Rat   195 QGQVYTCGHGRGGRLGHGDEQTCLVPRLVE---GLSGHSCSQVAAAKDHTVVLTEDGCVYTFGLN 256

  Fly   264 TDHQLGVRDAAEQLTQFKEVVALRDKGASDLVRVIACDQHSIAYGSRCVYVWGANQGQFG--INS 326
            |.||||:..........:::.|...||.: ::.|.|...|::.:....||..|.|.||.|  ::.
  Rat   257 TFHQLGIIPPPSSCNVPRQIQAKYLKGRT-IIGVAAGRFHTVLWTREAVYTLGLNGGQLGHLLDP 320

  Fly   327 N-TPSITVPTLIK-LPAK-TTIRFVEANNAATVIYNEEKIITLC--YADKTRYIKTPNYEDLKSI 386
            | ...:|.|..:. |..| ..:..|.|::.|||.......|.|.  |..|....|..|   ||.:
  Rat   321 NGEKCVTTPRQVSALHHKDIAVSLVAASDGATVCVTTRGDIYLLADYQCKKMATKQLN---LKKV 382

  Fly   387 SVMGGNL------KNSTKGSAAALKLLMLTETNVVYLWYENTQQFYRCNFSPIRLHQIKKILYKC 445
            .|.||.:      ::.|:.....:.:|.:.....|:.|...:....:|.::..|...|..|....
  Rat   383 LVSGGCMEYKVDPEHLTENGGQKICILAMDGAGRVFCWRSLSSSLKQCRWAYPRQVSISDIALNR 447

  Fly   446 NQVMVLSEDGCVYRGKCNQIALPSSALQEKSRGSLDNWQDNDQNKTEISREHVI--RIELQRVPN 508
            |:::.:::||..::||..:....:|   ||....|.|...:..:.:.:|..:.:  ||.|:::|.
  Rat   448 NEILFVTQDGEGFKGKWFEDKRKNS---EKKADILPNLHHSSSDVSCVSDTNSVYERIRLEKLPF 509

  Fly   509 IDRATYIFCDEGFSSFAVLQ-ESHTKYFRKPSLPRRE--HSFKKLLHETSDCDAVHDVVFHVDGE 570
            ..||..:..|....:||:|| :..|..:..|.:....  ..|.|||.||.:.|:.|||.|.|...
  Rat   510 AHRAVSVSTDPSGCNFAILQSDPKTSLYEIPVVSSSSFFEEFGKLLRETDEMDSFHDVTFQVGNR 574

  Fly   571 KFAAHKFIIYSRAPGLRDLIRCYLD-------KDIYLNFDHLTG-----------KMFELILNHI 617
            .|.|||:::..|:...:.|   :|.       .|:|...:...|           .:||.:|..:
  Rat   575 LFPAHKYVLAVRSDFFQKL---FLSDGTLLELTDVYRKDEDAAGCHLFVVEKVHPDLFEYLLQFM 636

  Fly   618 YSSYWPTEDDIDCIQQSLGP------------ANPQQRTRTCEMFLPHLEK--FQLV-------- 660
            |:      |..|.:.....|            .:|:.|.......:...:|  |::.
  Rat   637 YT------DTCDFLTHGFKPRMIMNKKSEDSKGSPESRLHAVNCHVDDKQKSAFEVYRSNQAHTL 695

  Fly   661 --------------------ELTKYVQSYVRDHQFPLPN------------------ARKLFNRL 687
                                :..|.:|:..:  :|.|.|                  |:|..|:|
  Rat   696 SERQKSKPKSSKKGKGVGEDDPVKMLQNVAK--KFGLSNLSSRLDGVRYENEKINVIAKKTGNKL 758

  Fly   688 YRSDH--PELYDVRIVCKDGKVLGAHKCMLVARLEYFEMMFMHLWAERSSVTMEGVP--AEYMEP 748
            ..|..  ..||||.:...|||....|||:|.||||||..|....|.|.||.....:|  ||.::.
  Rat   759 KLSQKKCSFLYDVTMKSVDGKEFPCHKCVLCARLEYFHSMLSRSWIEASSCAALEMPIQAEILKV 823

  Fly   749 VLDYLYSLDNEAFCKQGYLETFLYNMITICDQYFIESLQNVCESLILDKISIRKCGEMLEFAAMY 813
            :|||||: |.....|:.....|:.:::.:.||..|..|:.:||..:.:.::::....:||||:||
  Rat   824 ILDYLYT-DEAVVIKESQNVDFVCSVLVVADQLLITRLKEMCEVALAENLTLKNAAMLLEFASMY 887

  Fly   814 NCKILQKGCMDFICQNLSRVLCYRSIEQCDGETLKCLNDHYRKMFKRVFDYRQITPFSEAIEDEL 878
            |.:.|:..|:.||..|::.:|..||::....:.||.|:..||||.. ..:.|.|||:.
  Rat   888 NAEQLKLSCLQFIGLNMAALLEARSLDVLSEDVLKDLSIFYRKMVP-AMERRVITPYQ------- 944

  Fly   879 LLSFVDGCDVDLNYRMDAESKLKQ----------------AAKHKQKDLRKQDARHQYEQQAISS 927
                 ||.|:......|.|..||:                ..:.|:|..::.|:...|....|..
  Rat   945 -----DGPDISCVQAEDGEVFLKEEISLEPNHSETMFKKAKTRAKKKPRKRSDSSGGYNLSDIIQ 1004

  Fly   928 MMRSLSISESTQGTEVPSSPQDSARSEDKNWSRV----------------VDKKDQKRKLAETAL 976
            ...|..:.:|.:...|.|.|:......:.:::.|                .||.:.|.|     .
  Rat  1005 SPPSAGLLKSAKTNSVESLPELLTSDSEGSYAGVGSPRDLQSPDFTAGFHSDKVEGKAK-----P 1064

  Fly   977 KVNNTLKHEDPPTQE-LVPIERKPLKEQTPP--PPSH------------ETEPTTP--------L 1018
            .||.|   ..|.|:| |.|.|:.|..:..|.  |.|.            ...|.:|        :
  Rat  1065 YVNGT---PLPWTREDLKPWEKSPTTKSAPQFIPSSRVDTSGSSSWVAGSCSPVSPPVVDLRTIM 1126

  Fly  1019 SKSYNLDFSSLTPQSQ---------KLSQKQRK--RLSSESKSWRTNN--PPLVEQSSTPVAVPN 1070
            ....|.......|:|.         ||||||||  .|:::..:..||:  |.|...|.:|..| |
  Rat  1127 ETEANRQKYGAAPKSNLGKIISHGIKLSQKQRKMMALTTKENNSGTNSMEPILTAPSKSPKPV-N 1190

  Fly  1071 AWGVTTTPSGSFNDSFTS---------PTTGS----------STDPTSFANMMR--GHATS---- 1110
            ||....:||.|   ||.:         |..||          .|:.:...|:.|  .|.|.
  Rat  1191 AWAPLHSPSSS---SFRNFLLEEKKPVPGRGSGDHVKKVCFKGTENSPALNVARCSPHGTPGLES 1252

  Fly  1111 --------------------STTPTDQSQSFSRILADEKRQRESYERMRNKSLVHTQIEERAIAE 1155
                                :.:|.....:|:.|:.:|::|..:..|.|.|.|...|:||.||.:
  Rat  1253 NHVSDFPLVDSPNPWLSSSLAASPAVAPVTFASIVEEERQQEAALIRSREKPLALIQVEEHAIQD 1317

  Fly  1156 LREFYNVDNIDDETITIAR 1174
            |..||......||.:.:.|
  Rat  1318 LLVFYEAFGNPDEFVIVER 1336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8060	NP_611117.2	ANKYR	<51..141	CDD:440430	30/89 (34%)
		ANK repeat	56..87	CDD:293786	9/30 (30%)
		ANK repeat	89..121	CDD:293786	15/31 (48%)
		ATS1	140..>355	CDD:444065	72/225 (32%)
		BTB_POZ	543..643	CDD:453885	30/131 (23%)
		BTB2_POZ_IBtk	691..802	CDD:349611	39/114 (34%)
		BACK_IBtk	798..857	CDD:350575	20/58 (34%)
Ibtk	NP_001414686.1	None