DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8060 and Sergef

DIOPT Version :9

Sequence 1:NP_611117.2 Gene:CG8060 / 36824 FlyBaseID:FBgn0034113 Length:1189 Species:Drosophila melanogaster
Sequence 2:XP_006541006.1 Gene:Sergef / 27414 MGIID:1351630 Length:465 Species:Mus musculus


Alignment Length:420 Identity:93/420 - (22%)
Similarity:156/420 - (37%) Gaps:80/420 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   152 GSNKNYNLGIGNEQNTNTPQAVDFFRKSNLWLEQVALGAYHSLFCDKKGHLYAVGHGKGGRLGIG 216
            |:|....||:|::::...||.:..|.::.. ::.|..|..||......|.|:..|..|.|:||:|
Mouse    22 GANSYGQLGLGHKEDVFLPQQLSDFCQAGC-IKSVTGGGGHSAVVTDGGDLFVCGLNKDGQLGLG 85

  Fly   217 -LENSLPAPKRVKVSSKLSGDSIQCISVSRQHSLVLTHQSLVFACGLNTDHQLGVRDAAEQLTQF 280
             .|..|    |..:...|.|..|:.::.....:::||.:..|.:||.|...||||.....:....
Mouse    86 HTEEVL----RFTICKPLRGCPIRQVACGWDFTIMLTEKGQVLSCGSNAFGQLGVPHGPRKCVVP 146

  Fly   281 KEVVALRDKGASDLVRVIACDQHSI---AYGSRCVYVWGANQGQFGINSNTPSITVPTLIKLPAK 342
            :.:..||:|    :|.|.|..:|::   |.||  |:.||......| ....|...:|..:.....
Mouse   147 QAIECLREK----VVCVAAGLRHALATTATGS--VFQWGTGLASSG-RRLCPGQNLPLFLTAKEP 204

  Fly   343 TTIRFVEANNAATVIYNEEKIITLC---------------YADKTRYIKTPN------YEDLKSI 386
            :.:..:|.:.|...:...:...:|.               .|.:..::..|.      ::|.|..
Mouse   205 SRVTGLENSTAVCAVAGSDHSASLTDTGELYVWGRNKHGQLASRAVFLPLPQRIEAHYFQDEKVT 269

  Fly   387 SVMGGNLKNSTKGSAAALKLLMLTETNVVYLWYENTQQFYRCNFSPI--RLHQIKKILYKCNQVM 449
            :|..|           ...|:..|||..|:.|       .|.::..:  ||...:.      |..
Mouse   270 AVWSG-----------WTHLVAKTETGKVFTW-------GRADYGQLGRRLEPPEA------QKP 310

  Fly   450 VLSEDGCVYRGKCNQIALPSSAL---QEKSRGSLDN----------WQDNDQNKTEISREHVI-- 499
            |..:....::|..|.:..|...|   .|.|.||..|          |..|:........|..:  
Mouse   311 VEQDSSLAFQGPQNSVPSPLHCLTGATEISCGSEHNLAVIRDKCCSWGWNEHGMCGDGTESNVWT 375

  Fly   500 RIELQRV-PNIDRATYIFCDEGFSSFAVLQ 528
            ...:|.: |:..|...:.|..| .|.||.|
Mouse   376 PTPVQALPPSPSRLLLVGCGAG-HSLAVCQ 404

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8060NP_611117.2 ANK <46..138 CDD:238125
ANK repeat 56..87 CDD:293786
Ank_4 57..111 CDD:290365
ANK repeat 89..121 CDD:293786
Ank_2 95..>138 CDD:289560
RCC1 147..195 CDD:278826 12/42 (29%)
RCC1 199..251 CDD:278826 14/52 (27%)
BTB 547..>635 CDD:295341
BTB 684..795 CDD:279045
BTB 697..798 CDD:197585
SPOP_C_like 798..>834 CDD:269810
SergefXP_006541006.1 ATS1 22..370 CDD:227511 83/383 (22%)
RCC1 356..402 CDD:366085 9/46 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5184
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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