DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8060 and Nek9

DIOPT Version :9

Sequence 1:NP_611117.2 Gene:CG8060 / 36824 FlyBaseID:FBgn0034113 Length:1189 Species:Drosophila melanogaster
Sequence 2:NP_660120.2 Gene:Nek9 / 217718 MGIID:2387995 Length:984 Species:Mus musculus


Alignment Length:377 Identity:76/377 - (20%)
Similarity:129/377 - (34%) Gaps:102/377 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    62 HMSASTARYEILEWL-LNHGAYINGQ----DYESGSSPLH------RALYYGSIDCAVLLLRYGA 115
            |.:..|...|:..|: :..|..::||    |..|...|.|      :|::  .:.|.        
Mouse   380 HFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASYRQPKHVEKLQGKAIH--QVSCG-------- 434

  Fly   116 SLELLDEDTRCPLQAICRKCDDDDLATDSQNDVLVWGSNKNYNLGIGNEQNTNT--PQAVDFFRK 178
                                ||..:....:..:..:||:....:|:........  |..::||..
Mouse   435 --------------------DDFTVCVTDEGQLYAFGSDYYGCMGVDKVSGPEVLEPMQLNFFLS 479

  Fly   179 SNLWLEQVALGAYHSLFCDKKGHLYAVGHGKGGRLGIGLENSLPAPKRVKVSSKLSGDSIQCISV 243
            :.  :|||:.|..|.:...:...:|:.|.|:.||||:..|.....|:||.|...|...::||   
Mouse   480 NP--VEQVSCGDNHVVVLTRNKEVYSWGCGEYGRLGLDSEEDYYTPQRVDVPKALIIVAVQC--- 539

  Fly   244 SRQHSLVLTHQSLVFACGLNTDHQLGVRDAAEQLTQFKEVVALRDKGASDLVRVIACDQHSIAYG 308
            ....:.:||....|.|||||..::||:                                      
Mouse   540 GCDGTFLLTQSGKVLACGLNEFNKLGL-------------------------------------- 566

  Fly   309 SRCVYVWGANQGQFGINSN-----TPSITVPTLIKLPAKTTIRFVEANNAATVIYNEEKIITLCY 368
                     ||...||.::     .|..|..||.|..:...||.:......|...:|...:....
Mouse   567 ---------NQCMSGIINHEAYHEVPYTTSFTLAKQLSFYKIRTIAPGKTHTAAIDERGRLLTFG 622

  Fly   369 ADKTRYIKTPNYEDLKSISVMGGNL--KNSTKGSAAALKLLMLTETNVVYLW 418
            .:|...:...||:....|:::||.|  |...:.|......:..|:.|.::.|
Mouse   623 CNKCGQLGVGNYKKRLGINLLGGPLGGKQVIRVSCGDEFTIAATDDNHIFAW 674

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8060NP_611117.2 ANK <46..138 CDD:238125 14/86 (16%)
ANK repeat 56..87 CDD:293786 7/29 (24%)
Ank_4 57..111 CDD:290365 13/59 (22%)
ANK repeat 89..121 CDD:293786 5/37 (14%)
Ank_2 95..>138 CDD:289560 4/48 (8%)
RCC1 147..195 CDD:278826 11/49 (22%)
RCC1 199..251 CDD:278826 15/51 (29%)
BTB 547..>635 CDD:295341
BTB 684..795 CDD:279045
BTB 697..798 CDD:197585
SPOP_C_like 798..>834 CDD:269810
Nek9NP_660120.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 14..43
STKc_Nek9 51..296 CDD:270860
S_TKc 52..296 CDD:214567
RCC1 1 388..444 13/85 (15%)
RCC1 389..441 CDD:278826 13/81 (16%)
RCC1 444..495 CDD:278826 11/52 (21%)
RCC1 2 445..498 11/54 (20%)
RCC1 3 499..550 17/53 (32%)
RCC1 500..547 CDD:278826 15/49 (31%)
RCC1 4 551..615 20/110 (18%)
RCC1 5 616..668 10/51 (20%)
RCC1 616..664 CDD:278826 9/47 (19%)
RCC1 6 669..726 2/6 (33%)
Interaction with NEK6. /evidence=ECO:0000250 732..896
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 744..790
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 940..984
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5184
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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