DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8060 and K11D2.1

DIOPT Version :9

Sequence 1:	NP_611117.2	Gene:	CG8060 / 36824	FlyBaseID:	FBgn0034113	Length:	1189	Species:	Drosophila melanogaster
Sequence 2:	NP_001368497.1	Gene:	K11D2.1 / 187290	WormBaseID:	WBGene00010768	Length:	278	Species:	Caenorhabditis elegans

Alignment Length:	301	Identity:	63/301 - (20%)
Similarity:	106/301 - (35%)	Gaps:	105/301 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 YYGSI---DCAVLLLRYGASLELLDEDTRCP---LQAIC----------------RKCDDD---- 138
            ::|||   .|.:.|:.......|..|..:.|   ....|                |:.||.
Worm     8 WFGSISVDSCKITLIFDAPMTSLASETIQLPDEVKHVACTHLHMAILMKHEKLAVRRLDDFEGNL 72

  Fly   139 ---DLATDSQNDVLVWGSNKNY------------------NLGIGNEQNTNTPQAVDFFRKSNLW 182
               ||.||.  |||:..:::..                  ::||..::| |....:.|     .|
Worm    73 TFLDLHTDL--DVLLVATSREIYAVERSGTSSEIVKILVDSVGISPKKN-NLANKIQF-----PW 129

  Fly   183 ---LEQVALGAYHSLFCDKKGHLYAVGHGKGGRLGIGLENSLPAPKRVKVSSKLSGDSIQCISVS 244
               :.:.|.|....:|.|..|:|:::|.|..|.||:||...:..|..::   :|.|..|:.::..
Worm   130 PVRIVEAAAGHDFLIFRDTTGNLFSMGTGTRGELGVGLIRRVDEPVHIE---QLVGIRIKKVACG 191

  Fly   245 RQHSLVLTHQSLVFACGLNTDHQLGVRDAAEQLTQFKEVVALRDKGASDLVRV------------ 297
            ..|::.||.....:..|.|...|||                 :|||::::..|
Worm   192 GWHTVALTEGGDAYTWGWNRYGQLG-----------------KDKGSTEVYPVLIDPEEEKFGEE 239

  Fly   298 ----IACDQHS---IAYGSRCVYVWGANQGQFGINSNTPSI 331
                :||.:|:   :.......:|.|.|.        ||.|
Worm   240 NILDVACTEHNTQIVIKTGHAPFVLGTNP--------TPPI 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8060	NP_611117.2	ANK	<46..138	CDD:238125	11/59 (19%)
		ANK repeat	56..87	CDD:293786
		Ank_4	57..111	CDD:290365	4/13 (31%)
		ANK repeat	89..121	CDD:293786	6/23 (26%)
		Ank_2	95..>138	CDD:289560	11/59 (19%)
		RCC1	147..195	CDD:278826	11/68 (16%)
		RCC1	199..251	CDD:278826	14/51 (27%)
		BTB	547..>635	CDD:295341
		BTB	684..795	CDD:279045
		BTB	697..798	CDD:197585
		SPOP_C_like	798..>834	CDD:269810
K11D2.1	NP_001368497.1	ATS1	<118..>259	CDD:227511	36/166 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900