DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8060 and RCC1

DIOPT Version :9

Sequence 1:NP_611117.2 Gene:CG8060 / 36824 FlyBaseID:FBgn0034113 Length:1189 Species:Drosophila melanogaster
Sequence 2:NP_001041659.1 Gene:RCC1 / 1104 HGNCID:1913 Length:452 Species:Homo sapiens


Alignment Length:293 Identity:74/293 - (25%)
Similarity:114/293 - (38%) Gaps:55/293 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   136 DDDDLATDSQNDVLVWGSNKNYNLGIGNEQNTNTPQAVDFFRKSNLWLE--------QVALGAYH 192
            |....|......|.:|||.::.|..||         .::..:||.:.::        :||.|..|
Human   159 DSHTAAL
TDDGRVFLWGSFRDNNGVIG---------LLEPMKKSMVPVQVQLDVPVVKVASGNDH 214

  Fly   193 SLFCDKKGHLYAVGHGKGGRLG------------IGLENSLPAPKRVKVSSKLSGDSI--QCISV 243
            .:.....|.||.:|.|:.|:||            .|||..| .||.|.:.|:.|...:  |....
Human   215 LVML
TADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLL-VPKCVMLKSRGSRGHVRFQDAFC 278

  Fly   244 SRQHSLVLTHQSLVFACGLNTDHQLGVRDA-----AEQLTQFKEVVALRDKGASDLVRVIACDQH 303
            ....:..::|:..|:..||:..||||....     .:.||.||       ......|.......|
Human   279 GAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFK-------NSTKSWVGFSGGQHH 336

  Fly   304 SIAYGSR-CVYVWG-ANQGQFGINSNTPSITVPTLI-KLPAKTTIRFVEANNAATVIYNEEKI-I 364
            ::...|. ..|..| |..|:.|:.......::|||| :|||.:::..     .|:|.|...|. .
Human   337 TVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPAVSSVAC-----GASVGYAVTKDGR 396

  Fly   365 TLCYADKTRY-IKTPNYEDLKS-ISVMGGNLKN 395
            ...:...|.| :.|...||..| :.:||..|:|
Human   397 VFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLEN 429

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8060NP_611117.2 ANK <46..138 CDD:238125 1/1 (100%)
ANK repeat 56..87 CDD:293786
Ank_4 57..111 CDD:290365
ANK repeat 89..121 CDD:293786
Ank_2 95..>138 CDD:289560 1/1 (100%)
RCC1 147..195 CDD:278826 13/55 (24%)
RCC1 199..251 CDD:278826 18/65 (28%)
BTB 547..>635 CDD:295341
BTB 684..795 CDD:279045
BTB 697..798 CDD:197585
SPOP_C_like 798..>834 CDD:269810
RCC1NP_001041659.1 RCC1 66..113 CDD:278826
RCC1 116..165 CDD:278826 1/5 (20%)
RCC1 168..218 CDD:278826 13/58 (22%)
RCC1 221..286 CDD:278826 18/65 (28%)
RCC1 289..340 CDD:278826 13/57 (23%)
RCC1 343..386 CDD:278826 12/47 (26%)
RCC1 394..445 CDD:278826 10/36 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5184
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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