Protein Alignment Atg9 and ATG9

DIOPT Version :9

• Sequence 1: NP_001261023.1
• Gene: Atg9 / 36821
• FlyBaseID: FBgn0034110
• Length: 852
• Species: Drosophila melanogaster
• Sequence 2: NP_010132.1
• Gene: ATG9 / 851406
• SGDID: S000002308
• Length: 997
• Species: Saccharomyces cerevisiae
• Alignment Length: 742
• Identity: 171/742 - (23%)
• Similarity: 318/742 - (42%)
• Gaps: 141/742 - (19%)

  Fly    13 EEAASPFLEHHPSTGQGPSK-TQDAKANAAAAHLD--------PLGEHGLEQPLDEHDTEHEGED 68
            |:...|....|......|.: ||....::.|.|.|        |...:|.:    :|.|::.|..
Yeast   182 EDGKRPLFFRHILQNNRPQRDTQKLFTSSNAIHHDKDKSANNGPRNINGNQ----KHGTKYFGSA 242

  Fly    69 T-PRNSGVMIH----------------------------------MVPETGRARWNHIEDLDSFF 98
            | ||.:|..::                                  .|.|....:|.::|:||.|.
Yeast   243 TQPRFTGSPLNNTNRFTKLFPLRKPNLLSNISVLNNTPEDRINTLSVKERALWKWANVENLDIFL 307

  Fly    99 SRMYQYQQKHGFTVIVVDEMLQVLEFGFVVWLLAFVMHCVRFDVLFGDTPPGGLNPNKTTLSDVM 163
            ..:|.|...:||..|:::::|.:....|||::..::.|||.:..|          |....:||::
Yeast   308 QDVYNYYLGNGFYCIILEKILNICTLLFVVFVSTYMGHCVDYSKL----------PTSHRVSDII 362

  Fly   164 YPTGECLAN--------FTWVTYLVVFIAAIYLGIRLLKMVYHITQYADIKRFYNSALHIEDSDL 220
              ..:|.:|        |.|:.|..|.       ::::::.:.:.:.::::.||...|:|.|.:|
Yeast   363 --IDKCYSNSITGFTKFFLWMFYFFVI-------LKIVQLYFDVQKLSELQNFYKYLLNISDDEL 418

  Fly   221 DNFTWHEVQQRIRRVQAEQHMCID------KESLTELDIYHRVLRFKNYLVALMNKQLLPVRFHI 279
            ....|..|.|::..::.:..|..:      |..:...|:.:|::|.:|||:||.|..:|.:...|
Yeast   419 QTLPWQNVIQQLMYLKDQNAMTANVVEVKAKNRIDAHDVANRIMRRENYLIALYNSDILNLSLPI 483

  Fly   280 PLYGEVVSLSRGMLFNIDFILFRGPGSPFQNNWQLRDEFAVRSNQTELAQRLSKLILGVALLNLV 344
            ||:...| |::.:.:||:..:.   |..|..:..::......|.:....:.|.|..:....||::
Yeast   484 PLFRTNV-LTKTLEWNINLCVM---GFVFNESGFIKQSILKPSQREFTREELQKRFMLAGFLNII 544

  Fly   345 LAPVIFVWQLIYFSFSYANILRKEPGALGLRTWSNYGRLYLRHFNELDHELDARLNRAYDYADRY 409
            |||.:..:.::.:.|.|.|..:..||::|.|.::.......|.:|||.|....|::.:...|::|
Yeast   545 LAPFLVTYFVLLYFFRYFNEYKTSPGSIGARQYTPIAEWKFREYNELYHIFKKRISLSTTLANKY 609

  Fly   410 LNSFSSPLAAVIAKNLLFISGGLLLLILALGIYE-EHVFQVE-----HLLAILAGLGAIGVVCRT 468
            ::.|......:..|.:.||.|..:.::..|.::: |:....|     .::..:..||||..|.|.
Yeast   610 VDQFPKEKTNLFLKFVSFICGSFVAILAFLTVFDPENFLNFEITSDRSVIFYITILGAIWSVSRN 674

  Fly   469 LIPDENLVWCPEQLMTAILAHVHYLPSEWRQQAHTTKVRQEFSNFFQFKAGYLLSEIFSPFVTPF 533
            .|..|..|:.||:.:..:..:.||||.||..:.|..:::.||...:..:...||.|:.|..:|||
Yeast   675 TITQEYHVFDPEETLKELYEYTHYLPKEWEGRYHKEEIKLEFCKLYNLRIVILLRELTSLMITPF 739

  Fly   534 VLIFVFRPKAIELVRFFRTFTVSVRGVGNVCSFAQMDVRKHGNPDWQLTSELEE--MTRATA--- 593
            ||.|.....|..:|.|||..:..|.|:|.||.:|..:::   |.|.:.|..::|  :|:..|
Yeast   740 VLWFSLPSSAGRIVDFFRENSEYVDGLGYVCKYAMFNMK---NIDGEDTHSMDEDSLTKKIAVNG 801

  Fly   594 ----------QQPQQEPQQQSLAGGKTEMSLLRF--TLNNPE-----WQMPKE------------ 629
                      :...::...:.||..|...|.:.|  ..:|.|     :|:|.:
Yeast   802 SHTLNSKRRSKFTAEDHSDKDLANNKMLQSYVYFMDDYSNSENLTGKYQLPAKKGYPNNEGDSFL 866

  Fly   630 ------AKQFLRG-------VREHAVG 643
                  .|||..|       :.:||:|
Yeast   867 NNKYSWRKQFQPGQKPELFRIGKHALG 893

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atg9	NP_001261023.1	APG9	219..573	CDD:282028	97/365 (27%)
ATG9	NP_010132.1	APG9	295..776	CDD:397984	129/503 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343086
Domainoid	1	1.000	205	1.000	Domainoid score	I530
eggNOG	1	0.900	-	-		E1_KOG2173
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	208	1.000	Inparanoid score	I820
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002167
OrthoInspector	1	1.000	-	-		oto100137
orthoMCL	1	0.900	-	-		OOG6_102183
Panther	1	1.100	-	-	LDO	PTHR13038
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R112
SonicParanoid	1	1.000	-	-		X1638
TreeFam	1	0.960	-	-
	13	12.780