DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7747 and PPIL4

DIOPT Version :9

Sequence 1:NP_611113.1 Gene:CG7747 / 36820 FlyBaseID:FBgn0034109 Length:517 Species:Drosophila melanogaster
Sequence 2:NP_624311.1 Gene:PPIL4 / 85313 HGNCID:15702 Length:492 Species:Homo sapiens


Alignment Length:233 Identity:82/233 - (35%)
Similarity:128/233 - (54%) Gaps:18/233 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly   282 VRLNTNLGPLNLELFCDQTPRACDNFIKHCANGYYNNVMFHRSIRNFIVQGGDPTGSGSGGESIW 346
            |.|.|.||.:.::|:.::.||||.||:|.|...|||..:.|...|:||:|.|||||:|.|||||:
Human     3 VLLETTLGDVVIDLYTEERPRACLNFLKLCKIKYYNYCLIHNVQRDFIIQTGDPTGTGRGGESIF 67

  Fly   347 GKK-------FEDEFKPNLTHTGRGVLSMANSGPNTNGSQFFITY-RSCKHLDGKHTIFGKLVGG 403
            |:.       ||.|..|.:.|..:|.:||.|:|.:.:||||.||. .:..:|||.||:||::..|
Human    68 GQLYGDQASFFEAEKVPRIKHKKKGTVSMVNNGSDQHGSQFLITTGENLDYLDGVHTVFGEVTEG 132

  Fly   404 LDTLQKMENIEVDNKDRPIEDIIIESSQVFVNPFAEAAEQLAKEREEEA------AGK----EEI 458
            :|.::|:....||....|.:||.|..:.:..:||.:..:.|..:|..|.      :|:    |||
Human   133 MDIIKKINETFVDKDFVPYQDIRINHTVILDDPFDDPPDLLIPDRSPEPTREQLDSGRIGADEEI 197

  Fly   459 VKKEEQQKRMKEPLKVYREGVGKYLKLQTVAKKPEAPL 496
            ...:.:.....|.:|..:|...:.:.|:.|...|:|.:
Human   198 DDFKGRSAEEVEEIKAEKEAKTQAILLEMVGDLPDADI 235

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7747NP_611113.1 RING 25..238 CDD:302633
cyclophilin_RING 281..439 CDD:238904 68/164 (41%)
PPIL4NP_624311.1 cyclophilin_RRM 4..161 CDD:238902 65/156 (42%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 167..188 3/20 (15%)
RRM_PPIL4 237..319 CDD:240681
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 368..406
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 423..492
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0652
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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