Protein Alignment CG7747 and PPIL4

DIOPT Version :10

• Sequence 1: NP_611113.1
• Gene: CG7747 / 36820
• FlyBaseID: FBgn0034109
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: NP_624311.1
• Gene: PPIL4 / 85313
• HGNCID: 15702
• Length: 492
• Species: Homo sapiens
• Alignment Length: 233
• Identity: 82/233 - (35%)
• Similarity: 128/233 - (54%)
• Gaps: 18/233 - (7%)

  Fly   282 VRLNTNLGPLNLELFCDQTPRACDNFIKHCANGYYNNVMFHRSIRNFIVQGGDPTGSGSGGESIW 346
            |.|.|.||.:.::|:.::.||||.||:|.|...|||..:.|...|:||:|.|||||:|.|||||:
Human     3 VLLETTLGDVVIDLYTEERPRACLNFLKLCKIKYYNYCLIHNVQRDFIIQTGDPTGTGRGGESIF 67

  Fly   347 GKK-------FEDEFKPNLTHTGRGVLSMANSGPNTNGSQFFITY-RSCKHLDGKHTIFGKLVGG 403
            |:.       ||.|..|.:.|..:|.:||.|:|.:.:||||.||. .:..:|||.||:||::..|
Human    68 GQLYGDQASFFEAEKVPRIKHKKKGTVSMVNNGSDQHGSQFLITTGENLDYLDGVHTVFGEVTEG 132

  Fly   404 LDTLQKMENIEVDNKDRPIEDIIIESSQVFVNPFAEAAEQLAKEREEEA------AGK----EEI 458
            :|.::|:....||....|.:||.|..:.:..:||.:..:.|..:|..|.      :|:    |||
Human   133 MDIIKKINETFVDKDFVPYQDIRINHTVILDDPFDDPPDLLIPDRSPEPTREQLDSGRIGADEEI 197

  Fly   459 VKKEEQQKRMKEPLKVYREGVGKYLKLQTVAKKPEAPL 496
            ...:.:.....|.:|..:|...:.:.|:.|...|:|.:
Human   198 DDFKGRSAEEVEEIKAEKEAKTQAILLEMVGDLPDADI 235

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7747	NP_611113.1	RING-Ubox_PPIL2	41..113	CDD:438325
		RING_Ubox	104..162	CDD:473075
		cyclophilin_RING	281..439	CDD:238904	68/164 (41%)
PPIL4	NP_624311.1	cyclophilin_RRM	4..161	CDD:238902	65/156 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	167..188		3/20 (15%)
		RRM_PPIL4	237..319	CDD:409681
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	368..406
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	423..492