DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7747 and CPR5

DIOPT Version :9

Sequence 1:	NP_611113.1	Gene:	CG7747 / 36820	FlyBaseID:	FBgn0034109	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_010590.3	Gene:	CPR5 / 851898	SGDID:	S000002712	Length:	225	Species:	Saccharomyces cerevisiae

Alignment Length:	205	Identity:	77/205 - (37%)
Similarity:	119/205 - (58%)	Gaps:	17/205 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   263 AAIIDDDLVKYERVKKKGYVRLN---TNLGPLNLELFCDQTPRACDNFIKHCAN-----GYYNNV 319
            |....:|..:...:..|.|..:|   ..:|.:.:.|:...||:..:||.:...:     ||.|::
Yeast    19 AIFAKEDTAEDPEITHKVYFDINHGDKQIGRIVMGLYGLTTPQTVENFYQLTISRDPKMGYLNSI 83

  Fly   320 MFHRSIRNFIVQGGDPT-GSGSGGESIWGKKFEDEFKPNLTHTGRGVLSMANSGPNTNGSQFFIT 383
             |||.|.||::||||.| .||.||:||:|..|:|| ..::.|...|.|||||.|.||||||||||
Yeast    84 -FHRVIPNFMIQGGDFTHRSGIGGKSIFGNTFKDE-NFDVKHDKPGRLSMANRGKNTNGSQFFIT 146

  Fly   384 YRSCKHLDGKHTIFGKLVGGLDTLQKMENIEVDNKDRPIED-IIIESSQVFVNPF-----AEAAE 442
            ...|..|||||.:||:::.|:|.:..:||::.|:::.|::: ||:||.::...|.     |:..|
Yeast   147 TVPCPWLDGKHVVFGEVLDGMDVVHYIENVKTDSRNMPVKEVIIVESGELETVPLDNKDAAKLQE 211

  Fly   443 QLAKEREEEA 452
            ::..|..|.|
Yeast   212 EIKAEASEAA 221

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7747	NP_611113.1	RING	25..238	CDD:302633
CG7747	NP_611113.1	cyclophilin_RING	281..439	CDD:238904	69/172 (40%)
CPR5	NP_010590.3	cyclophilin	34..194	CDD:412213	68/161 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810