DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7747 and Ppig

DIOPT Version :9

Sequence 1:	NP_611113.1	Gene:	CG7747 / 36820	FlyBaseID:	FBgn0034109	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_113981.2	Gene:	Ppig / 83624	RGDID:	620315	Length:	752	Species:	Rattus norvegicus

Alignment Length:	249	Identity:	79/249 - (31%)
Similarity:	128/249 - (51%)	Gaps:	39/249 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   285 NTNLGPLNLELFCDQTPRACDNFIKHCANG-----------YYNNVMFHRSIRNFIVQGGD-PTG 337
            |...|.:..|||.|..|:.|:||...|...           :|.:.:|||.:::|:||||| ..|
  Rat    18 NQPAGRVVFELFSDVCPKTCENFRCLCTGEKGTGKSTQKPLHYKSCLFHRVVKDFMVQGGDFSEG 82

  Fly   338 SGSGGESIWGKKFEDE-FKPNLTHTGRGVLSMANSGPNTNGSQFFITYRSCKHLDGKHTIFGKLV 401
            :|.|||||:|..|||| |.  :.|....:|||||.|.:|||||||||.:...||||.|.:||:::
  Rat    83 NGRGGESIYGGFFEDESFA--VKHNKEFLLSMANRGKDTNGSQFFITTKPTPHLDGHHVVFGQVI 145

  Fly   402 GGLDTLQKMENIEVDNKDRPIEDIIIESSQVFVNPFAEAAEQLAKEREEEAAGK----------- 455
            .|.:.::::||.:.|...:|..::.|.|....| |.::..::..|..:..::..
  Rat   146 SGQEVVREIENQKTDAASKPFAEVRILSCGELV-PKSKVKKEEKKRHKSSSSSSSSDSDSSSDSQ 209

  Fly   456 -------EEIVKKEEQQKRMKEPLKVYREGVGKYLKLQTVAKK-PEAPLTSAQA 501
                   .|...:|:.:||.|:    :|:...|:.|.:...|| .::|.:.::|
  Rat   210 SSSDSSDSESASEEKSRKRKKK----HRKNSRKHKKEKKKRKKSKKSPSSESEA 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7747	NP_611113.1	RING	25..238	CDD:302633
CG7747	NP_611113.1	cyclophilin_RING	281..439	CDD:238904	66/166 (40%)
Ppig	NP_113981.2	cyclophilin	8..175	CDD:412213	64/158 (41%)
Ppig	NP_113981.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	182..752		13/82 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810