DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7747 and Ppih

DIOPT Version :9

Sequence 1:	NP_611113.1	Gene:	CG7747 / 36820	FlyBaseID:	FBgn0034109	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_001103600.1	Gene:	Ppih / 66101	MGIID:	106499	Length:	188	Species:	Mus musculus

Alignment Length:	134	Identity:	61/134 - (45%)
Similarity:	83/134 - (61%)	Gaps:	12/134 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   288 LGPLNLELFCDQTPRACDNFIKHCANGY--------YNNVMFHRSIRNFIVQGGD-PTGSGSGGE 343
            :|.:.:|||.|..|:..:||.:.|...:        |....|||.|::|::|||| ..|.|:|..
Mouse    24 VGRMKIELFADVVPKTAENFRQFCTGEFRKDGVPIGYKGSTFHRVIKDFMIQGGDFVNGDGTGVA 88

  Fly   344 SIWGKKFEDE-FKPNLTHTGRGVLSMANSGPNTNGSQFFITYRSCKHLDGKHTIFGKLVGGLDTL 407
            ||:...|.|| ||  |.|:..|:||||||||:|||.|||||...|..|||||.:|||::.||..:
Mouse    89 SIYRGPFADENFK--LRHSAPGLLSMANSGPSTNGCQFFITCSKCDWLDGKHVVFGKIIDGLLVM 151

  Fly   408 QKME 411
            :|:|
Mouse   152 RKIE 155

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7747	NP_611113.1	RING	25..238	CDD:302633
CG7747	NP_611113.1	cyclophilin_RING	281..439	CDD:238904	61/134 (46%)
Ppih	NP_001103600.1	cyclophilin_ABH_like	11..155	CDD:238907	60/132 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900