Protein Alignment CG7747 and Ppil2

DIOPT Version :10

• Sequence 1: NP_611113.1
• Gene: CG7747 / 36820
• FlyBaseID: FBgn0034109
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: XP_006522510.1
• Gene: Ppil2 / 66053
• MGIID: 2447857
• Length: 564
• Species: Mus musculus
• Alignment Length: 490
• Identity: 269/490 - (54%)
• Similarity: 369/490 - (75%)
• Gaps: 12/490 - (2%)

  Fly     1 MGKRQHQKDKMYLTYTEWSELYGGKKVESLENDHVKFKRLPFEHCCITMAPYEMPYCDLQGNVFE 65
            ||||||||||||:|..|::..|||:|.:.   ....|:||||:||.:::.|:..|.|..:|.||:
Mouse     1 MGKRQHQKDKMYITCAEYTHFYGGRKPDI---SQTSFRRLPFDHCSLSLQPFVYPVCTPEGVVFD 62

  Fly    66 YEAILKFLKTFKVNPITGQKMDSKSLVKLNFHRNANDEYHCPALFKPFSKNSHIVAVATTGNVYC 130
            ...|:.:||.:..||.||:|:|.|||:||||.:|:..:||||.|:..|:.|:||||:.||||||.
Mouse    63 LLNIVPWLKKYGTNPSTGEKLDGKSLIKLNFAKNSEGQYHCPVLYSVFTDNTHIVAIRTTGNVYT 127

  Fly   131 WEAIDQLNIKTKNWKDLVDDTPFQRKDIITIQDPQKLEKYDISTFYHIKKNLRVLTEEEQQERKN 195
            :||::|||||.||.:||:.|.||.|:||||:|||..|:|:::|.|:|:|.|:|::..:|::.:::
Mouse   128 YEAVEQLNIKAKNLRDLLTDEPFSRQDIITLQDPTNLDKFNVSNFFHVKNNMRIIDPDEEKAKQD 192

  Fly   196 PASGRIKTMNLETKETLEQLQQDYQPAEEEAST----SKRTADKFNAAHYSTGAVAASFTSTAMV 256
            | |..:|..|.||:|||::|.::::..|..|:|    .|:..|:.||||||||.|:|||||||||
Mouse   193 P-SYYLKNTNSETRETLQELYKEFKGDEILAATMRPPEKKKVDQLNAAHYSTGKVSASFTSTAMV 256

  Fly   257 PVSQIEAAIIDDDLVKYERVKKKGYVRLNTNLGPLNLELFCDQTPRACDNFIKHCANGYYNNVMF 321
            |.:..|||:||:|:::|:.|||||||||:||.|.|||||.||.||:.|:||||.|...||:..:|
Mouse   257 PETTHEAAVIDEDVLRYQFVKKKGYVRLHTNKGDLNLELHCDLTPKTCENFIKLCKKQYYDGTIF 321

  Fly   322 HRSIRNFIVQGGDPTGSGSGGESIWGKKFEDEFKPNLTHTGRGVLSMANSGPNTNGSQFFITYRS 386
            |||||||::|||||||:|:||||.|||.|:|||:|||:|||||||||||||||||.||||||:||
Mouse   322 HRSIRNFVIQGGDPTGTGTGGESFWGKPFKDEFRPNLSHTGRGVLSMANSGPNTNKSQFFITFRS 386

  Fly   387 CKHLDGKHTIFGKLVGGLDTLQKMENIEVDNK-DRPIEDIIIESSQVFVNPFAEAAEQLAKERE- 449
            |.:||.||||||::|||.|||..|||:|.|.| |||.|:::|.::.|||:|:.||..|:|:||:
Mouse   387 CAYLDKKHTIFGRVVGGFDTLTAMENVESDPKTDRPKEEVLICTTTVFVDPYEEADAQIAQERKK 451

  Fly   450 -EEAAGKEEIVKKEEQQKRMKEPLKVYREGVGKYL 483
             :.....|..||..:.|...:.| :.||:|||||:
Mouse   452 TQHQVDPEAKVKMSQPQPGNQGP-QTYRQGVGKYI 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7747	NP_611113.1	RING-Ubox_PPIL2	41..113	CDD:438325	32/71 (45%)
		RING_Ubox	104..162	CDD:473075	36/57 (63%)
		cyclophilin_RING	281..439	CDD:238904	109/158 (69%)
Ppil2	XP_006522510.1	RING-Ubox_PPIL2	38..110	CDD:438325	32/71 (45%)
		RING_Ubox	101..159	CDD:473075	36/57 (63%)
		cyclophilin_RING	281..440	CDD:238904	109/158 (69%)