Protein Alignment CG7747 and RANBP2

DIOPT Version :10

• Sequence 1: NP_611113.1
• Gene: CG7747 / 36820
• FlyBaseID: FBgn0034109
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: XP_005264059.1
• Gene: RANBP2 / 5903
• HGNCID: 9848
• Length: 3258
• Species: Homo sapiens
• Alignment Length: 270
• Identity: 96/270 - (35%)
• Similarity: 133/270 - (49%)
• Gaps: 50/270 - (18%)

  Fly   171 DISTFYHIKKN-LRVLTEEEQQERKNPASGRIKTMNLE----TKETLEQLQQDYQPAEEEASTSK 230
            ||...:|..|| .|:|...:|..:........|||.|:    :...|.....||  |:.||...:
Human  2991 DIKILWHTMKNYYRILMRRDQVFKVCANHVITKTMELKPLNVSNNALVWTASDY--ADGEAKVEQ 3053

  Fly   231 RTADKFNAAHYSTGAVAASFTSTAMVPVSQIEAAIIDDDLVKYERVKKKGYVRL------NTN-- 287
            .      |..:.|..||..|..|       .|..  ..:|:|.:    ||:|.|      .||
Human  3054 L------AVRFKTKEVADCFKKT-------FEEC--QQNLMKLQ----KGHVSLAAELSKETNPV 3099

  Fly   288 -----------LGPLNLELFCDQTPRACDNFIKHCA--NGY-YNNVMFHRSIRNFIVQGGDPT-G 337
                       ||.:.:|||.:..||..:||...|.  .|: :.|.:|||.|.:|:.||||.| .
Human  3100 VFFDVCADGEPLGRITMELFSNIVPRTAENFRALCTGEKGFGFKNSIFHRVIPDFVCQGGDITKH 3164

  Fly   338 SGSGGESIWGKKFEDEFKPNLTHTGRGVLSMANSGPNTNGSQFFITYRSCKHLDGKHTIFGKLVG 402
            .|:||:||:|.||||| ..::.|||.|:|||||.|.|||.|||.||.:..:|||.||.:||.:..
Human  3165 DGTGGQSIYGDKFEDE-NFDVKHTGPGLLSMANQGQNTNNSQFVITLKKAEHLDFKHVVFGFVKD 3228

  Fly   403 GLDTLQKMEN 412
            |:||::|:|:
Human  3229 GMDTVKKIES 3238

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7747	NP_611113.1	RING-Ubox_PPIL2	41..113	CDD:438325
		RING_Ubox	104..162	CDD:473075
		cyclophilin_RING	281..439	CDD:238904	67/155 (43%)
RANBP2	XP_005264059.1	LapB	<33..222	CDD:442196
		TPR repeat	59..89	CDD:276809
		TPR repeat	94..123	CDD:276809
		RanBD1_RanBP2-like	1186..1302	CDD:270203
		zf-RanBP	1351..1381	CDD:395516
		RanBP2-type Zn finger	1355..1375	CDD:275375
		zf-RanBP	1415..1443	CDD:395516
		RanBP2-type Zn finger	1419..1438	CDD:275375
		zf-RanBP	1479..1508	CDD:395516
		RanBP2-type Zn finger	1483..1502	CDD:275375
		zf-RanBP	1543..1572	CDD:395516
		RanBP2-type Zn finger	1547..1566	CDD:275375
		zf-RanBP	1606..1635	CDD:395516
		RanBP2-type Zn finger	1610..1629	CDD:275375
		zf-RanBP	1665..1694	CDD:395516
		RanBP2-type Zn finger	1669..1688	CDD:275375
		zf-RanBP	1724..1753	CDD:395516
		RanBP2-type Zn finger	1728..1747	CDD:275375
		zf-RanBP	1781..1809	CDD:395516
		RanBP2-type Zn finger	1785..1804	CDD:275375
		RanBD2_RanBP2-like	2027..2143	CDD:269998
		RanBD3_RanBP2-like	2324..2440	CDD:270204
		IR1-M	2657..2719	CDD:463488
		IR1-M	2735..2791	CDD:463488
		RanBD4_RanBP2-like	2959..3075	CDD:269999	25/100 (25%)
		cyclophilin_ABH_like	3098..3256	CDD:238907	63/142 (44%)