DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7747 and ppil4

DIOPT Version :9

Sequence 1:	NP_611113.1	Gene:	CG7747 / 36820	FlyBaseID:	FBgn0034109	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_001121802.1	Gene:	ppil4 / 554886	ZFINID:	ZDB-GENE-030131-6251	Length:	454	Species:	Danio rerio

Alignment Length:	238	Identity:	82/238 - (34%)
Similarity:	126/238 - (52%)	Gaps:	28/238 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   282 VRLNTNLGPLNLELFCDQTPRACDNFIKHCANGYYNNVMFHRSIRNFIVQGGDPTGSGSGGESIW 346
            |.|.|.||.:.::|:.::.|:|..||:|.|...|||..:.|...|:||:|.|||||:|.||||::
Zfish     3 VLLETTLGDIVIDLYTEERPKASLNFLKLCKIKYYNYCLIHNVQRDFIIQTGDPTGTGRGGESVF 67

  Fly   347 GKK-------FEDEFKPNLTHTGRGVLSMANSGPNTNGSQFFITY-RSCKHLDGKHTIFGKLVGG 403
            .|.       ||.|..|.:.|..:|.:||.|:|.:.:||||.||. .:..:|||.||:||::..|
Zfish    68 CKLYGDQARFFESEKMPRIKHRKKGTVSMVNNGSDQHGSQFLITTGENVDYLDGVHTVFGEVTEG 132

  Fly   404 LDTLQKMENIEVDNKDRPIEDIIIESSQVFVNPFAEAA-------------EQLAKER--EEEAA 453
            :|.|.|:....|||...|.:||.|..:.:..:||.:.|             :||...|  .:||.
Zfish   133 MDVLAKINETFVDNDFIPFQDIRINHTVILDDPFDDPAGLPVPDRSPEPTKQQLDSGRIGADEAI 197

  Fly   454 GKEEIVKKEEQQKRMKEPLKVYREGVGKYLKLQTVAKKPEAPL 496
            ..:|....||..:.:|:     :|...:.:.|:.|...|:|.:
Zfish   198 NDDEGKDPEELDELIKD-----KEAKTQAILLEMVGDLPDADI 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7747	NP_611113.1	RING	25..238	CDD:302633
CG7747	NP_611113.1	cyclophilin_RING	281..439	CDD:238904	67/164 (41%)
ppil4	NP_001121802.1	cyclophilin_RRM	4..169	CDD:238902	66/164 (40%)
		RRM	172..>320	CDD:223796	14/69 (20%)
		RRM_PPIL4	237..319	CDD:240681
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810