DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7747 and ppig

DIOPT Version :9

Sequence 1:	NP_611113.1	Gene:	CG7747 / 36820	FlyBaseID:	FBgn0034109	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_998629.1	Gene:	ppig / 406773	ZFINID:	ZDB-GENE-040426-2822	Length:	687	Species:	Danio rerio

Alignment Length:	279	Identity:	84/279 - (30%)
Similarity:	135/279 - (48%)	Gaps:	59/279 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   285 NTNLGPLNLELFCDQTPRACDNFIKHCANG-----------YYNNVMFHRSIRNFIVQGGD-PTG 337
            |...|.:.:|||.|..|:.|:||...|...           :|....|||.:::|::|||| ..|
Zfish    18 NVPAGRVVIELFSDVCPKTCENFRCLCTGEKGVGKTTQKPLHYKGTPFHRIVKDFMIQGGDFSEG 82

  Fly   338 SGSGGESIWGKKFED-EFKPNLTHTGRGVLSMANSGPNTNGSQFFITYRSCKHLDGKHTIFGKLV 401
            :|.|||||:|..||| .|  ::.||...:|||||.|.:|||||||||.:...||||.|.:||:::
Zfish    83 NGRGGESIYGGFFEDGSF--SMKHTKEFLLSMANRGKDTNGSQFFITTKPTPHLDGIHVVFGQVI 145

  Fly   402 GGLDTLQKMENIEVDNKDRPIEDIII-------------------ESSQVFVNPFAEA---AEQL 444
            .|.|.::.:|:.:.|...||..::.:                   :||....:..:::   :|:.
Zfish   146 TGQDVIRMIESQKTDTNSRPYAEVKVLNCGELVPKSKAKKEKKKHQSSSESEDSSSDSSSDSEES 210

  Fly   445 AKEREEEAAGKEEIVKKEEQQKRMKE------------------PLKVYREGVGKYLKLQTVAKK 491
            .||::.....|:|..||:|.:.:.||                  |.:|......::|    :.:.
Zfish   211 EKEKKRRKKHKKEHKKKKESKHKKKEKKGSDEEEAEPQAVSTIRPEEVPPIPENRFL----MRRS 271

  Fly   492 PEAPLTSAQAAKKKKLANG 510
            ||.|....|:.:|.|:.:|
Zfish   272 PEKPKEEEQSKEKDKVDSG 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7747	NP_611113.1	RING	25..238	CDD:302633
CG7747	NP_611113.1	cyclophilin_RING	281..439	CDD:238904	64/185 (35%)
ppig	NP_998629.1	cyclophilin	8..175	CDD:294131	62/158 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900