DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7747 and CG8336

DIOPT Version :9

Sequence 1:	NP_611113.1	Gene:	CG7747 / 36820	FlyBaseID:	FBgn0034109	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_001261636.1	Gene:	CG8336 / 39121	FlyBaseID:	FBgn0036020	Length:	383	Species:	Drosophila melanogaster

Alignment Length:	152	Identity:	58/152 - (38%)
Similarity:	83/152 - (54%)	Gaps:	16/152 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   289 GPLNLELFCDQTPRACDNFIKHCANG----------YYNNVMFHRSIRNFIVQGGDPT-GSGSGG 342
            |.:.:||..|..|:..:||...|...          :|....||:..|.|:||.||.. ..||.|
  Fly    29 GRMIIELRKDVVPKTAENFRALCTGECGIGTLGKPLHYKGTKFHKIKRVFVVQSGDVVKNDGSSG 93

  Fly   343 ESIWGKKFEDE-FKPNLTHTGRGVLSMANSG-PNTNGSQFFITYRSCKHLDGKHTIFGKLVGGLD 405
            |||:|..|:|| |:  |:|...||:||||.| ||:|.|||||:...|::|:|.:.:.|:::.||.
  Fly    94 ESIYGPVFDDENFE--LSHNEEGVVSMANYGKPNSNNSQFFISAAGCENLNGTNVVVGRVLRGLG 156

  Fly   406 TLQKMENIEVDNKDRPIEDIII 427
            .:.:||....|..| |...|:|
  Fly   157 IVAEMEQNCTDEGD-PTAPIVI 177

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7747	NP_611113.1	RING	25..238	CDD:302633
CG7747	NP_611113.1	cyclophilin_RING	281..439	CDD:238904	58/152 (38%)
CG8336	NP_001261636.1	cyclophilin	15..181	CDD:294131	58/152 (38%)
		TPR repeat	285..315	CDD:276809
		TPR_19	300..369	CDD:291240
		TPR_1	320..353	CDD:278916
		TPR repeat	320..346	CDD:276809
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447174
Domainoid	1	1.000	81	1.000	Domainoid score	I449
eggNOG	1	0.900	-	-		E1_COG0652
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.740