Protein Alignment CG7747 and Ppil2

DIOPT Version :10

• Sequence 1: NP_611113.1
• Gene: CG7747 / 36820
• FlyBaseID: FBgn0034109
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: XP_063126732.1
• Gene: Ppil2 / 360746
• RGDID: 1309484
• Length: 526
• Species: Rattus norvegicus
• Alignment Length: 531
• Identity: 283/531 - (53%)
• Similarity: 387/531 - (72%)
• Gaps: 19/531 - (3%)

  Fly     1 MGKRQHQKDKMYLTYTEWSELYGGKKVESLENDHVKFKRLPFEHCCITMAPYEMPYCDLQGNVFE 65
            ||||||||||||:|..|::..|||:|.:..:   ..|:||||:||.:::.|:..|.|..:|.||:
  Rat     1 MGKRQHQKDKMYITCAEYTHFYGGRKPDITQ---TSFRRLPFDHCSLSLQPFVYPVCTPEGVVFD 62

  Fly    66 YEAILKFLKTFKVNPITGQKMDSKSLVKLNFHRNANDEYHCPALFKPFSKNSHIVAVATTGNVYC 130
            ...|:.:||.:..:|.||:|:|.|||:||||.:|:..:||||.|:..|:.|:||||:.||||||.
  Rat    63 LLNIVPWLKKYGTDPSTGEKLDGKSLIKLNFAKNSEGQYHCPVLYSVFTDNTHIVAIRTTGNVYT 127

  Fly   131 WE-----AIDQLNIKTKNWKDLVDDTPFQRKDIITIQDPQKLEKYDISTFYHIKKNLRVLTEEEQ 190
            :|     |::|||||.||.:||:.|.||.|:||||:|||..|:|:::|:|:|:|.|:|::..:|:
  Rat   128 YEVDPLAAVEQLNIKAKNLRDLLTDEPFSRQDIITLQDPTNLDKFNVSSFFHVKNNMRMIDPDEE 192

  Fly   191 QERKNPASGRIKTMNLETKETLEQLQQDYQPAEEEAST----SKRTADKFNAAHYSTGAVAASFT 251
            :.:::| |..:|..|.||:|||::|.::::..|..|:|    .|:..|:.||||||||.|:||||
  Rat   193 KAKQDP-SYYLKNTNAETRETLQELYKEFKGDEILAATMKPPEKKKVDQLNAAHYSTGKVSASFT 256

  Fly   252 STAMVPVSQIEAAIIDDDLVKYERVKKKGYVRLNTNLGPLNLELFCDQTPRACDNFIKHCANGYY 316
            ||||||.:..|||:||:|:::|:.|||||||||:||.|.|||||.||.||:.|:||||.|...||
  Rat   257 STAMVPETTHEAAVIDEDVLRYQFVKKKGYVRLHTNKGDLNLELHCDLTPKTCENFIKLCKKQYY 321

  Fly   317 NNVMFHRSIRNFIVQGGDPTGSGSGGESIWGKKFEDEFKPNLTHTGRGVLSMANSGPNTNGSQFF 381
            :..:||||||||::|||||||:|:||||.|||.|:|||:|||:|||||||||||||||||.||||
  Rat   322 DGTIFHRSIRNFVIQGGDPTGTGTGGESYWGKPFKDEFRPNLSHTGRGVLSMANSGPNTNKSQFF 386

  Fly   382 ITYRSCKHLDGKHTIFGKLVGGLDTLQKMENIEVDNK-DRPIEDIIIESSQVFVNPFAEAAEQLA 445
            ||:|||.:||.||||||::|||.|||..|||:|.|.| |||.|::.|.::.|||:|:.||..|:|
  Rat   387 ITFRSCAYLDKKHTIFGRVVGGFDTLTAMENVESDPKTDRPKEEVRICTTTVFVDPYEEADAQIA 451

  Fly   446 KERE--EEAAGKEEIVKKEEQQKRMKEPLKVYREGVGKYLK-LQTVAKKPEAPLTS-AQAAKKKK 506
            :||:  :.....|...|..:.|...:.| :.||:|||||:. ..|.....|.|.|| |....||:
  Rat   452 QERKKTQHQVDPEAKAKTNQPQPGNQGP-QTYRQGVGKYINPAATKRAAEEEPSTSTAIPTAKKR 515

  Fly   507 LANGFGDFSSW 517
            .:.||||||||
  Rat   516 PSRGFGDFSSW 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7747	NP_611113.1	RING-Ubox_PPIL2	41..113	CDD:438325	31/71 (44%)
		RING_Ubox	104..162	CDD:473075	36/62 (58%)
		cyclophilin_RING	281..439	CDD:238904	109/158 (69%)
Ppil2	XP_063126732.1	None